Patents by Inventor Dae-Kee Kwon

Dae-Kee Kwon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neuro-progenitor produced from an SCNT-derived ES cell
    Patent number: 9476064
    Abstract: An embryonic stem cell line derived from a nucleus-transferred oocyte prepared by transferring a nucleus of a human somatic cell into an enucleated human oocyte may differentiate into various desired cell types.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: October 25, 2016
    Assignee: H BION CO., LTD.
    Inventors: Sung-Il Roh, Woo-Suk Hwang, Byeong-Chun Lee, Sung-Keun Kang, Young-June Ryu, Eu-Gene Lee, Soon-Woong Kim, Dae-Kee Kwon, Hee-Sun Kwon, Ja-Min Koo, Eul-Soon Park, Youn-Young Hwang, Hyun-Soo Yoon, Jong-Hyuk Park, Sun-Jong Kim
  • Transgenic pig expressing sTNFR1-Fc genes and the uses thereof
    Patent number: 9357754
    Abstract: The present invention relates to a transgenic pig that expresses sTNFR1-Fc, wherein a gene encoding sTNFR1-Fc, which is a fusion protein of the extracellular domain of human soluble tumor necrosis factor receptor (sTNFR1) and an immunoglobulin Fc region, is introduced; a method for preparing the same; an organ isolated from the transgenic pig; a somatic donor cell line inserted with sTNFR1-Fc gene; a method for preparing a blood sample comprising sTNFR1-Fc; and a method for preparing human sTNFR1-Fc from the blood sample of the transgenic pig. As the transgenic pig can suppress immune response and inflammatory response by secreting an inhibitory substance that suppresses the activity of TNF-? in blood, it can be effectively used for xenograft. Furthermore, since the transgenic pig has a blood type O, it can be transplanted for suppressing inflammatory response, regardless of a blood type of recipient.
    Type: Grant
    Filed: January 20, 2012
    Date of Patent: June 7, 2016
    Assignee: SNU R&DB FOUNDATION
    Inventors: Curie Ahn, Byeong Chun Lee, Jong Ik Hwang, Jae Seok Yang, Byoung Gon Moon, Goo Jang, Bum Rae Cho, Ok Jae Koo, Sol Ji Park, Jung Taek Kang, Dae Kee Kwon
  • Transgenic pig in which HO-1 and TNFR1-Fc are simultaneously expressed, and method for producing same
    Patent number: 9018439
    Abstract: The present invention relates to a method for producing a transgenic pig in which immune rejection response is inhibited, and in which human HO-1 genes and TNFR1-Fe fusion genes are simultaneously expressed. The present invention also relates to a transgenic pig for organ transplantation, which is produced by the method, and in which immune rejection response is inhibited. The present invention also relates to a somatic-cell-donating cell strain for producing the transgenic pig, and to a method for producing organs, from the transgenic pig, in which the immune rejection response is inhibited.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: April 28, 2015
    Assignee: Hanwha Advanced Materials Corporation
    Inventors: Curie Ahn, Byeong Chun Lee, Jong Ik Hwang, Jae Seok Yang, Goo Jang, Bum Rae Cho, Ok Jae Koo, Jung Taek Kang, Dae Kee Kwon
  • EMBRYONIC STEM CELL LINE AND METHOD FOR PREPARING THE SAME
    Publication number: 20140154800
    Abstract: An embryonic stem cell line derived from a nucleus-transferred oocyte prepared by transferring a nucleus of a human somatic cell into an enucleated human oocyte may differentiate into various desired cell types.
    Type: Application
    Filed: November 26, 2013
    Publication date: June 5, 2014
    Applicant: H. Bion Co., Ltd.
    Inventors: Sung-Il ROH, Woo-Suk HWANG, Byeong-Chun LEE, Sung-Keun KANG, Young-June RYU, Eu-Gene LEE, Soon-Woong KIM, Dae-Kee KWON, Hee-Sun KWON, Ja-Min KOO, Eul-Soon PARK, Youn-Young HWANG, Hyun-SOO YOON, Jong-Hyuk PARK, Sun-Jong KIM
  • Human embryonic stem cell line prepared by nuclear transfer of a human somatic cell into an enucleated human oocyte
    Patent number: 8647872
    Abstract: An embryonic stem cell line derived from a nucleus-transferred oocyte prepared by transferring a nucleus of a human somatic cell into an enucleated human oocyte may differentiate into various desired cell types.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: February 11, 2014
    Assignee: H. Bion Co., Ltd.
    Inventors: Sung-Il Roh, Woo-Suk Hwang, Byeong-Chun Lee, Sung-Keun Kang, Young-June Ryu, Eu-Gene Lee, Soon-Woong Kim, Dae-Kee Kwon, Hee-Sun Kwon, Ja-Min Koo, Eul-Soon Park, Youn-Young Hwang, Hyun-Soo Yoon, Jong-Hyuk Park, Sun-Jong Kim
  • TRANSGENIC PIG EXPRESSING STNFR1-FC GENES AND THE USES THEREOF
    Publication number: 20140026233
    Abstract: The present invention relates to a transgenic pig that expresses sTNFR1-Fc, wherein a gene encoding sTNFR1-Fc, which is a fusion protein of the extracellular domain of human soluble tumor necrosis factor receptor (sTNFR1) and an immunoglobulin Fc region, is introduced; a method for preparing the same; an organ isolated from the transgenic pig; a somatic donor cell line inserted with sTNFR1-Fc gene; a method for preparing a blood sample comprising sTNFR1-Fc; and a method for preparing human sTNFR1-Fc from the blood sample of the transgenic pig. As the transgenic pig can suppress immune response and inflammatory response by secreting an inhibitory substance that suppresses the activity of TNF-? in blood, it can be effectively used for xenograft. Furthermore, since the transgenic pig has a blood type O, it can be transplanted for suppressing inflammatory response, regardless of a blood type of recipient.
    Type: Application
    Filed: January 20, 2012
    Publication date: January 23, 2014
    Applicant: SNU R&DB FOUNDATION
    Inventors: Curie Ahn, Byeong Chun Lee, Jong Ik Hwang, Jae Seok Yang, Byoung Gon Moon, Goo Jang, Bum Rae Cho, Ok Jae Koo, Sol Ji Park, Jung Taek Kang, Dae Kee Kwon
  • Transgenic Pig in which HO-1 and TNFR1-Fc are Simultaneously Expressed, and Method for Producing Same
    Publication number: 20120278910
    Abstract: The present invention relates to a method for producing a transgenic pig in which immune rejection response is inhibited, and in which human HO-1 genes and TNFR1-Fe fusion genes are simultaneously expressed. The present invention also relates to a transgenic pig for organ transplantation, which is produced by the method, and in which immune rejection response is inhibited. The present invention also relates to a somatic-cell-donating cell strain for producing the transgenic pig, and to a method for producing organs, from the transgenic pig, in which the immune rejection response is inhibited.
    Type: Application
    Filed: December 21, 2010
    Publication date: November 1, 2012
    Applicant: HANWHA L&C CORPORATION
    Inventors: Curie Ahn, Byeong Chun Lee, Jong Ik Hwang, Jae Seok Yang, Goo Jang, Bum Rae Cho, Ok Jae Koo, Jung Taek Kang, Dae Kee Kwon
  • EMBRYONIC STEM CELL LINE AND METHOD FOR PREPARING THE SAME
    Publication number: 20120083032
    Abstract: An embryonic stem cell line derived from a nucleus-transferred oocyte prepared by transferring a nucleus of a human somatic cell into an enucleated human oocyte may differentiate into various desired cell types.
    Type: Application
    Filed: December 9, 2011
    Publication date: April 5, 2012
    Applicant: H. BION CO., LTD.
    Inventors: Sung-Il ROH, Woo-Suk HWANG, Byeong-Chun LEE, Sung-Keun KANG, Young-June RYU, Eu-Gene LEE, Soon-Woong KIM, Dae-Kee KWON, Hee-Sun KWON, Ja-Min KOO, Eul-Soon PARK, Youn-Young HWANG, Hyun-Soo YOON, Jong-Hyuk PARK, Sun-Jong KIM
  • Embryonic stem cell line and method for preparing the same
    Publication number: 20110065192
    Abstract: An embryonic stem cell line derived from a nucleus-transferred oocyte prepared by transferring a nucleus of a human somatic cell into an enucleated human oocyte may differentiate into various desired cell types.
    Type: Application
    Filed: November 20, 2009
    Publication date: March 17, 2011
    Applicant: H Bion Co., Ltd.
    Inventors: Sung-II Roh, Woo-Suk Hwang, Byeong-Chun Lee, Sung-Keun Kang, Young-June Ryu, Eu-Gene Lee, Soon-Woong Kim, Dae-Kee Kwon, Hee-Sun Kwon, Ja-Min Koo, Eul-Soon Park, Youn-Young Hwang, Hyun-Soo Yoon, Jong-Hyuk Park, Sun-Jong Kim
  • Embryonic Stem Cell Line and Method for Preparing the Same
    Publication number: 20070243610
    Abstract: An embryonic stem cell line derived from a nucleus-transferred oocyte prepared by transferring a nucleus of a human somatic cell into an enucleated human oocyte may differentiate into various desired cell types.
    Type: Application
    Filed: December 30, 2004
    Publication date: October 18, 2007
    Applicant: Seoul National University Industry Foundation
    Inventors: Sung-Il Roh, Woo-Suk Hwang, Byeong-Chun Lee, Sung-Keun Kang, Young-June Ryu, Eu-Gene Lee, Soon-Woong Kim, Dae-Kee Kwon, Hee-Sun Kwon, Ja-Min Koo, Eul-Soon Park, Youn-Young Hwang, Hyun-Soo Yoon, Jong-Hyuk Park, Sun-Jong Kim