Patents by Inventor Dae Kim

Dae Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMOLECULAR PROBES AND METHODS OF DETECTING GENE AND PROTEIN EXPRESSION
    Publication number: 20260125756
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Application
    Filed: July 21, 2025
    Publication date: May 7, 2026
    Inventors: Joseph M. BEECHEM, Dae KIM, Margaret HOANG, Mark GREGORY, Erin PIAZZA, Denise ZHOU
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20250277263
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: March 18, 2025
    Publication date: September 4, 2025
    Inventors: Dwayne DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG, Matthew WALSH, Gavin MEREDITH, Mark MCELWAIN, Peter SKENE, Cassandra BURKE
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20250236907
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: December 18, 2024
    Publication date: July 24, 2025
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Chemical compositions and methods of using same
    Patent number: 12281356
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: December 21, 2022
    Date of Patent: April 22, 2025
    Assignee: Bruker Spatial Biology, Inc.
    Inventors: Dwayne Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang, Matthew Walsh, Gavin Meredith, Mark McElwain, Peter Skene, Cassandra Burke
  • Chemical compositions and methods of using same
    Patent number: 12209275
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: January 28, 2025
    Assignee: Bruker Spatial Biology, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION
    Publication number: 20240279723
    Abstract: The present disclosure is based in part on probes, compositions, methods, and kits for simultaneous, multiplexed spatial detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell.
    Type: Application
    Filed: June 17, 2022
    Publication date: August 22, 2024
    Inventors: Lidan WU, Rustem KHAFIZOV, Evan Paul PERILLO, Dwayne DUNAWAY, Dae KIM, Joseph M. BEECHEM
  • Chemical compositions and methods of using same
    Patent number: 12049666
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: September 21, 2023
    Date of Patent: July 30, 2024
    Assignee: Bruker Spatial Biology, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20240084361
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: September 21, 2023
    Publication date: March 14, 2024
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Chemical compositions and methods of using same
    Patent number: 11821026
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: March 7, 2023
    Date of Patent: November 21, 2023
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • CHEMICAL COMPOSITIONS AND METHODS OF USING THE SAME
    Publication number: 20230366012
    Abstract: The present disclosure provides compositions and methods for the detection and identification of target nucleic acids within a tissue sample using fluorescent probes, wherein the probes comprise a target-binding domain and a barcode domain.
    Type: Application
    Filed: September 16, 2021
    Publication date: November 16, 2023
    Inventors: Shanshan HE, Dwayne L. DUNAWAY, Isabel LEE, Dae KIM, Joseph M. BEECHEM, Lidan WU
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20230257800
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: March 7, 2023
    Publication date: August 17, 2023
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION
    Publication number: 20230235384
    Abstract: The present disclosure is based in part on probes, compositions, methods, and kits for simultaneous, multiplexed spatial detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell.
    Type: Application
    Filed: June 17, 2021
    Publication date: July 27, 2023
    Inventors: Jonathan CHENG, Dwayne DUNAWAY, Mark GREGORY, Jaemyeong JUNG, Rustem KHAFIZOV, Dae KIM, Evan Paul PERILLO, Tushar RANE, Lidan WU
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20230220461
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: December 21, 2022
    Publication date: July 13, 2023
    Inventors: Dwayne DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG, Matthew WALSH, Gavin MEREDITH, Mark MCELWAIN, Peter SKENE, Cassandra Burke
  • BIOASSAY SUBSTRATE HAVING FIDUCIAL DOMAINS AND METHODS OF MANUFACTURE THEREOF
    Publication number: 20230149931
    Abstract: Embodiments of the present disclosure are directed to an array substrate which can be used in nucleic acid sequencing, which includes a plurality of fiducial domains (FDs). The disclosure also includes array substrate manufacturing methods and methods for making FDs on such substrates.
    Type: Application
    Filed: April 23, 2021
    Publication date: May 18, 2023
    Inventors: Camelia RUSU, Huawen WU, Joshua Dale BAKER, Jeffrey MARKS, Wesley C. CHANG, Dae KIM
  • Chemical compositions and methods of using same
    Patent number: 11549139
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: January 10, 2023
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang, Matthew Walsh, Gavin Meredith, Mark McElwain, Peter Skene, Cassandra Burke
  • Chemical compositions and uses thereof
    Patent number: 11473142
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: October 18, 2022
    Assignee: NanoString Technologies, Inc.
    Inventors: Joseph M. Beechem, Dae Kim, Margaret Hoang, Mark Gregory, Erin Piazza, Denise Zhou
  • VEHICLE CONTROL SYSTEM AND METHOD
    Publication number: 20220232350
    Abstract: A vehicle control system includes one or more of a HOV unit or an EOV unit. The HOV unit and/or the EOV unit may include functional devices, one or more processors, and a location signal receiver. The functional devices may perform one or more operations to control operation of a vehicle system on which the HOV unit and/or the EOV unit is disposed. The location signal receiver may receive location signals from an off-board source. The one or more processors may obtain or determine a location of the HOV unit and/or the EOV unit based on the location signals and to change a mode of operation of at least one of the functional devices responsive to the location changing from a first designated area or location to a different, second designated area or location.
    Type: Application
    Filed: April 8, 2022
    Publication date: July 21, 2022
    Inventors: Igor Abrosimov, Danial Rice, Dae Kim
  • BIOMOLECULAR PROBES AND METHODS OF DETECTING GENE AND PROTEIN EXPRESSION
    Publication number: 20220220555
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Application
    Filed: March 28, 2022
    Publication date: July 14, 2022
    Inventors: Joseph M. BEECHEM, Dae KIM, Margaret HOANG, Mark GREGORY, Erin PIAZZA, Denise ZHOU
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20220213532
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: March 21, 2022
    Publication date: July 7, 2022
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Chemical compositions and uses thereof
    Patent number: 11377689
    Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: July 5, 2022
    Assignee: NanoString Technologies, Inc.
    Inventors: Joseph M. Beechem, Dae Kim, Margaret Hoang, Mark Gregory, Erin Piazza, Denise Zhou