Patents by Inventor Daekyung Koh

Daekyung Koh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hexon isolated from simian adenovirus serotype 19, hypervariable region thereof and chimeric adenovirus using the same
    Patent number: 10066215
    Abstract: Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus comprising the same, and therapeutic use thereof provides a solution to the problem of safety and effective systemic treatment for developing gene therapeutic agents using adenovirus.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: September 4, 2018
    Assignee: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kyuhyun Lee, Seongtae Yun, Daekyung Koh, Hong-Kyu Lee, Eui-Cheol Jo
  • HEXON ISOLATED FROM SIMIAN ADENOVIRUS SEROTYPE 19, HYPERVARIABLE REGION THEREOF AND CHIMERIC ADENOVIRUS USING THE SAME
    Publication number: 20170051256
    Abstract: Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus comprising the same, and therapeutic use thereof provides a solution to the problem of safety and effective systemic treatment for developing gene therapeutic agents using adenovirus.
    Type: Application
    Filed: September 28, 2016
    Publication date: February 23, 2017
    Applicant: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kyuhyun LEE, Seongtae YUN, Daekyung KOH, Hong-Kyu LEE, Eui-Cheol JO
  • Hexon isolated from simian adenovirus serotype 19, hypervariable region thereof and chimeric adenovirus using the same
    Patent number: 9493745
    Abstract: Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus comprising the same, and therapeutic use thereof provides a solution to the problem of safety and effective systemic treatment for developing gene therapeutic agents using adenovirus.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: November 15, 2016
    Assignee: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kyuhyun Lee, Seongtae Yun, Daekyung Koh, Hong-Kyu Lee, Eui-Cheol Jo
  • Tumor specific promoter and oncolytic virus vector comprising the same
    Patent number: 9018182
    Abstract: Provided are tumor-specific promoters, oncolytic virus vectors and a pharmaceutical composition comprising the virus vector. The virus vector comprising the novel tumor-specific promoter shows excellent oncolytic effects on tumor cells, and thus it is useful for treating a cancer.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: April 28, 2015
    Assignees: Green Cross Corporation, Mogam Biotechnology Research Institute, Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Daekyung Koh, Seongtae Yun, Kyuhyun Lee, Hong-Kyu Lee, Mihee Hwang, Chae-Ok Yun, Eui-Cheol Jo
  • HEXON ISOLATED FROM SIMIAN ADENOVIRUS SEROTYPE 19, HYPERVARIABLE REGION THEREOF AND CHIMERIC ADENOVIRUS USING THE SAME
    Publication number: 20150111282
    Abstract: Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus comprising the same, and therapeutic use thereof provides a solution to the problem of safety and effective systemic treatment for developing gene therapeutic agents using adenovirus.
    Type: Application
    Filed: October 23, 2014
    Publication date: April 23, 2015
    Applicant: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kyuhyun LEE, Seongtae YUN, Daekyung KOH, Hong-Kyu LEE, Eui-Cheol JO
  • Expression vector suitable for expression of a coding sequence for gene therapy
    Patent number: 8628956
    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
    Type: Grant
    Filed: March 19, 2012
    Date of Patent: January 14, 2014
    Assignee: Mogam Biotechnology Research Institute
    Inventors: Daekyung Koh, Kyuhyun Lee, Hyeon Lee, Seongtae Yun, Eui-Cheol Jo
  • Expression vector suitable for expression of a coding sequence for gene therapy
    Patent number: 8617875
    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
    Type: Grant
    Filed: March 19, 2012
    Date of Patent: December 31, 2013
    Assignee: Mogam Biotechnology Research Institute
    Inventors: Daekyung Koh, Kyuhyun Lee, Hyeon Lee, Seongtae Yun, Eui-Cheol Jo
  • Expression vector for gene therapy
    Patent number: 8569051
    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
    Type: Grant
    Filed: March 19, 2012
    Date of Patent: October 29, 2013
    Assignee: Mogam Biotechnology Research Institute
    Inventors: Daekyung Koh, Kyuhyun Lee, Hyeon Lee, Seongtae Yun, Eui-Cheol Jo
  • TUMOR-SPECIFIC PROMOTER AND ONCOLYTIC VIRUS VECTOR COMPRISING THE SAME
    Publication number: 20130065952
    Abstract: Provided are tumor-specific promoters, oncolytic virus vectors and a pharmaceutical composition comprising the virus vector. The virus vector comprising the novel tumor-specific promoter shows excellent oncolytic effects on tumor cells, and thus it is useful for treating a cancer.
    Type: Application
    Filed: April 26, 2010
    Publication date: March 14, 2013
    Applicants: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE, GREEN CROSS CORPORATION
    Inventors: Daekyung Koh, Seongtae Yun, Kyuhyun Lee, Hong-Kyu Lee, Mihee Hwang, Chae-Ok Yun, Eui-Cheol Jo
  • HEXON ISOLATED FROM SIMIAN ADENOVIRUS SEROTYPE 19, HYPERVARIABLE REGION THEREOF AND CHIMERIC ADENOVIRUS USING THE SAME
    Publication number: 20130058897
    Abstract: Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus comprising the same, and therapeutic use thereof provides a solution to the problem of safety and effective systemic treatment for developing gene therapeutic agents using adenovirus.
    Type: Application
    Filed: April 14, 2010
    Publication date: March 7, 2013
    Applicant: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kyuhyun Lee, Seongtae Yun, Daekyung Koh, Hong-Kyu Lee, Eui-Cheol Jo
  • Expression vector suitable for expression of a coding sequence for gene therapy
    Patent number: 8309698
    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
    Type: Grant
    Filed: February 14, 2008
    Date of Patent: November 13, 2012
    Assignee: Mogam Biotechnology Research Institute
    Inventors: Daekyung Koh, Kyuhyun Lee, Hyeon Lee, Seongtae Yun, Eui-Cheol Jo
  • EXPRESSION VECTOR SUITABLE FOR EXPRESSION OF A CODING SEQUENCE FOR GENE THERAPY
    Publication number: 20120282687
    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
    Type: Application
    Filed: March 19, 2012
    Publication date: November 8, 2012
    Applicant: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Daekyung KOH, Kyuhyun LEE, Hyeon LEE, Seongtae YUN, Eui-Cheol JO
  • EXPRESSION VECTOR SUITABLE FOR EXPRESSION OF A CODING SEQUENCE FOR GENE THERAPY
    Publication number: 20120282685
    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
    Type: Application
    Filed: March 19, 2012
    Publication date: November 8, 2012
    Applicant: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Daekyung KOH, Kyuhyun LEE, Hyeon LEE, Seongtae YUN, Eui-Cheol JO
  • EXPRESSION VECTOR SUITABLE FOR EXPRESSION OF A CODING SEQUENCE FOR GENE THERAPY
    Publication number: 20120282686
    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
    Type: Application
    Filed: March 19, 2012
    Publication date: November 8, 2012
    Applicant: MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Daekyung KOH, Kyuhyun LEE, Hyeon LEE, Seongtae YUN, Eui-Cheol JO
  • EXPRESSION VECTOR SUITABLE FOR EXPRESSION OF A CODING SEQUENCE FOR GENE THERAPY
    Publication number: 20110045584
    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
    Type: Application
    Filed: February 14, 2008
    Publication date: February 24, 2011
    Applicant: Mogam Biotechnology Research Institute
    Inventors: Daekyung Koh, Kyuhyun Lee, Hyeon Lee, Seongtae Yun, Eui-Cheol Jo