Patents by Inventor Dafeng Chen
Dafeng Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11235321Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.Type: GrantFiled: October 10, 2019Date of Patent: February 1, 2022Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
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Publication number: 20200038855Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.Type: ApplicationFiled: October 10, 2019Publication date: February 6, 2020Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
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Patent number: 10441951Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.Type: GrantFiled: March 13, 2014Date of Patent: October 15, 2019Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
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Patent number: 10391425Abstract: A fluidic device and a method for degassing a fluidic device are presented. The fluidic device includes a plurality of fluidic components such as channels, chambers, and integrated valves and pumps, etc. A porous membrane is disposed on a degassing area of the fluidic device for removing gas (such as, for example, bubbles) contained in a liquid. A fluid control device monitors a pressure profile indicating a pressure in the fluidic device over time and applies a pressure differential between two sides of the membrane when activated. The membrane is permeable to gas in the fluidic device and is impermeable to liquids through the pores under the pressure differential. The disclosed method enables degassing large volume of gas at a high flow rate and provides a bubble free filling in a fluidic device which is critical to precision sample metering, mixing, fluid control, reaction, and detection, etc.Type: GrantFiled: June 16, 2015Date of Patent: August 27, 2019Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
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Patent number: 10105701Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.Type: GrantFiled: July 11, 2016Date of Patent: October 23, 2018Assignee: Siemens Healthcare Diagnostics Inc.Inventors: David J. Ledden, Dafeng Chen, James E. Rasmussen
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Publication number: 20170120164Abstract: A fluidic device and a method for degassing a fluidic device are presented. The fluidic device includes a plurality of fluidic components such as channels, chambers, and integrated valves and pumps, etc. A porous membrane is disposed on a degassing area of the fluidic device for removing gas (such as, for example, bubbles) contained in a liquid. A fluid control device monitors a pressure profile indicating a pressure in the fluidic device over time and applies a pressure differential between two sides of the membrane when activated. The membrane is permeable to gas in the fluidic device and is impermeable to liquids through the pores under the pressure differential. The disclosed method enables degassing large volume of gas at a high flow rate and provides a bubble free filling in a fluidic device which is critical to precision sample metering, mixing, fluid control, reaction, and detection, etc.Type: ApplicationFiled: June 16, 2015Publication date: May 4, 2017Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
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Publication number: 20160318019Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.Type: ApplicationFiled: July 11, 2016Publication date: November 3, 2016Applicant: Siemens Healthcare Diagnostics Inc.Inventors: David J. Ledden, Dafeng Chen, James E. Rasmussen
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Patent number: 9416776Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.Type: GrantFiled: March 13, 2014Date of Patent: August 16, 2016Assignee: Siemens Healthcare Diagnostics Inc.Inventors: David J. Ledden, Dafeng Chen, James E. Rasmussen
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Publication number: 20160038938Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.Type: ApplicationFiled: March 13, 2014Publication date: February 11, 2016Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
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Publication number: 20160008813Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.Type: ApplicationFiled: March 13, 2014Publication date: January 14, 2016Applicant: Siemens Healthcare Diagnostic Inc.Inventors: David J. LEDDEN, Dafeng CHEN, James E. RASMUSSEN
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Publication number: 20150352548Abstract: Microfluidic chips may include one or more microfluidic elements and one or more channels providing fluid communication throughout the microfluidic chip. The microfluidic chips may also include an identifier for identifying a predetermined configuration of the one or more microfluidic elements and the one or more channels from a set of predetermined different configurations of the one or more microfluidic elements and the one or more channels.Type: ApplicationFiled: January 27, 2014Publication date: December 10, 2015Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.Inventors: Manish Deshpande, James E. Rasmussen, Dafeng Chen
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Patent number: 8911938Abstract: Disclosed are preloaded analysis modules comprising reagents disposed within a barrier material capable of liberating the reagents, at a time advantageous to a reaction scheme, when exposed to certain activation conditions or reagents. Also disclosed are related methods for analyzing samples with such modules.Type: GrantFiled: December 10, 2008Date of Patent: December 16, 2014Assignee: The Trustees Of The University Of PennsylvaniaInventors: Michael G. Mauk, Haim H. Bau, Amanda W. Dyson, Sudhir Ramprasad, Dafeng Chen, Do Young Byun
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Publication number: 20090226911Abstract: Disclosed are preloaded analysis modules comprising reagents disposed within a barrier material capable of liberating the reagents, at a time advantageous to a reaction scheme, when exposed to certain activation conditions or reagents. Also disclosed are related methods for analyzing samples with such modules.Type: ApplicationFiled: December 10, 2008Publication date: September 10, 2009Applicant: The Trustees of the University of PennsylvaniaInventors: Michael G Mauk, Haim H. Bau, Amanda W. Dyson, Sudhir Ramprasad, Dafeng Chen, Do Young Byun