Patents by Inventor Dafeng Chen

Dafeng Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11235321
    Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: February 1, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
  • Publication number: 20200038855
    Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.
    Type: Application
    Filed: October 10, 2019
    Publication date: February 6, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
  • Patent number: 10441951
    Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: October 15, 2019
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
  • Patent number: 10391425
    Abstract: A fluidic device and a method for degassing a fluidic device are presented. The fluidic device includes a plurality of fluidic components such as channels, chambers, and integrated valves and pumps, etc. A porous membrane is disposed on a degassing area of the fluidic device for removing gas (such as, for example, bubbles) contained in a liquid. A fluid control device monitors a pressure profile indicating a pressure in the fluidic device over time and applies a pressure differential between two sides of the membrane when activated. The membrane is permeable to gas in the fluidic device and is impermeable to liquids through the pores under the pressure differential. The disclosed method enables degassing large volume of gas at a high flow rate and provides a bubble free filling in a fluidic device which is critical to precision sample metering, mixing, fluid control, reaction, and detection, etc.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: August 27, 2019
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
  • Patent number: 10105701
    Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: October 23, 2018
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: David J. Ledden, Dafeng Chen, James E. Rasmussen
  • Publication number: 20170120164
    Abstract: A fluidic device and a method for degassing a fluidic device are presented. The fluidic device includes a plurality of fluidic components such as channels, chambers, and integrated valves and pumps, etc. A porous membrane is disposed on a degassing area of the fluidic device for removing gas (such as, for example, bubbles) contained in a liquid. A fluid control device monitors a pressure profile indicating a pressure in the fluidic device over time and applies a pressure differential between two sides of the membrane when activated. The membrane is permeable to gas in the fluidic device and is impermeable to liquids through the pores under the pressure differential. The disclosed method enables degassing large volume of gas at a high flow rate and provides a bubble free filling in a fluidic device which is critical to precision sample metering, mixing, fluid control, reaction, and detection, etc.
    Type: Application
    Filed: June 16, 2015
    Publication date: May 4, 2017
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
  • Publication number: 20160318019
    Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: David J. Ledden, Dafeng Chen, James E. Rasmussen
  • Patent number: 9416776
    Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 16, 2016
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: David J. Ledden, Dafeng Chen, James E. Rasmussen
  • Publication number: 20160038938
    Abstract: A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 11, 2016
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Dafeng Chen, James E. Rasmussen, Manish Deshpande
  • Publication number: 20160008813
    Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 14, 2016
    Applicant: Siemens Healthcare Diagnostic Inc.
    Inventors: David J. LEDDEN, Dafeng CHEN, James E. RASMUSSEN
  • Publication number: 20150352548
    Abstract: Microfluidic chips may include one or more microfluidic elements and one or more channels providing fluid communication throughout the microfluidic chip. The microfluidic chips may also include an identifier for identifying a predetermined configuration of the one or more microfluidic elements and the one or more channels from a set of predetermined different configurations of the one or more microfluidic elements and the one or more channels.
    Type: Application
    Filed: January 27, 2014
    Publication date: December 10, 2015
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Manish Deshpande, James E. Rasmussen, Dafeng Chen
  • Patent number: 8911938
    Abstract: Disclosed are preloaded analysis modules comprising reagents disposed within a barrier material capable of liberating the reagents, at a time advantageous to a reaction scheme, when exposed to certain activation conditions or reagents. Also disclosed are related methods for analyzing samples with such modules.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: December 16, 2014
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Michael G. Mauk, Haim H. Bau, Amanda W. Dyson, Sudhir Ramprasad, Dafeng Chen, Do Young Byun
  • Publication number: 20090226911
    Abstract: Disclosed are preloaded analysis modules comprising reagents disposed within a barrier material capable of liberating the reagents, at a time advantageous to a reaction scheme, when exposed to certain activation conditions or reagents. Also disclosed are related methods for analyzing samples with such modules.
    Type: Application
    Filed: December 10, 2008
    Publication date: September 10, 2009
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Michael G Mauk, Haim H. Bau, Amanda W. Dyson, Sudhir Ramprasad, Dafeng Chen, Do Young Byun