Patents by Inventor Dafeng Chu

Dafeng Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide, complex of peptide and siRNA, and methods of use thereof
    Patent number: 11306313
    Abstract: A series of peptides and a peptide-siRNA complex are disclosed, wherein the peptide based complex effectively enhances delivery of siRNA molecules into the cells and release of siRNA in the cell, and improves siRNA mediated gene silencing efficiency of cellular targets. Pharmaceutical compositions that include the complex, as well as a use of the complex in the gene therapy field, are also disclosed.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: April 19, 2022
    Assignees: Positec Power Tools (Suzhou) Co LTD
    Inventors: Pu Chen, Dafeng Chu, Baoling Chen, Wen Xu, Ran Pan
  • PEPTIDE, COMPLEX OF PEPTIDE AND siRNA, AND METHODS OF USE THEREOF
    Publication number: 20200190518
    Abstract: A series of peptides and a peptide-siRNA complex are disclosed, wherein the peptide based complex effectively enhances delivery of siRNA molecules into the cells and release of siRNA in the cell, and improves siRNA mediated gene silencing efficiency of cellular targets. Pharmaceutical compositions that include the complex, as well as a use of the complex in the gene therapy field, are also disclosed.
    Type: Application
    Filed: January 24, 2020
    Publication date: June 18, 2020
    Inventors: Pu Chen, Dafeng CHU, Baoling CHEN, Wen XU, Ran PAN
  • Peptide, Complex of Peptide and siRNA, and Methods of Use Thereof
    Publication number: 20180355357
    Abstract: A series of peptides and a peptide-siRNA complex are disclosed, wherein the peptide based complex effectively enhances delivery of siRNA molecules into the cells and release of siRNA in the cell, and improves siRNA mediated gene silencing efficiency of cellular targets. Pharmaceutical compositions that include the complex, as well as a use of the complex in the gene therapy field, are also disclosed.
    Type: Application
    Filed: August 23, 2018
    Publication date: December 13, 2018
    Inventors: Pu Chen, Dafeng Chu, Baoling Chen, Wen Xu, Ran Pan
  • Peptide, complex of peptide and siRNA and use thereof
    Patent number: 10076575
    Abstract: A series of peptides and a peptide-siRNA complex are disclosed, wherein the peptide based complex effectively enhances delivery of siRNA molecules into the cells and release of siRNA in the cell, and improves siRNA mediated gene silencing efficiency of cellular targets. Pharmaceutical compositions that include the complex, as well as a use of the complex in the gene therapy field, are also disclosed.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: September 18, 2018
    Assignees: Positec Power Tools (Suzhou) Co LTD
    Inventors: Pu Chen, Dafeng Chu, Baoling Chen, Wen Xu, Ran Pan
  • Peptide, Complex of Peptide and SiRNA and Use Thereof
    Publication number: 20170119900
    Abstract: A series of peptides and a peptide-siRNA complex are disclosed, wherein the peptide based complex effectively enhances delivery of siRNA molecules into the cells and release of siRNA in the cell, and improves siRNA mediated gene silencing efficiency of cellular targets. Pharmaceutical compositions that include the complex, as well as a use of the complex in the gene therapy field, are also disclosed.
    Type: Application
    Filed: December 18, 2014
    Publication date: May 4, 2017
    Inventors: Pu Chen, Dafeng CHU, Baoling CHEN, Wen XU, Ran PAN
  • Injectable sustained-release microspheres of huperzine a compoounds
    Publication number: 20040266813
    Abstract: Sustained-release microspheres of Huperzine A compounds, the preparation and use thereof, said sustained-release microspheres comprise Huperzine A compounds represented by the formula (Ia) and biodegradably pharmaceutically acceptable polymer excipients, 1
    Type: Application
    Filed: August 23, 2004
    Publication date: December 30, 2004
    Inventors: Wanhui Liu, Jilun Song, Dafeng Chu, Ke Liu