Abstract: A system for detecting tissue contact and penetration depth. The system comprises a needle sheath having a needle sheath inner diameter and a needle sheath outer diameter. A first conductive region is disposed on the needle sheath inner diameter. A needle having a needle insulation layer on the outer diameter upon which a second conductive region is disposed within the first conductive region. A dielectric layer is disposed between the first conductive tube and the second conductive tube. A capacitance sensor is coupled to the first conductive region and the second conductive region.

Abstract: Various devices and methods for improving intravascular imaging are disclosed. In one embodiment, fluid dispersion devices are included on a catheter to improve dispersal of a flush solution within a flow of fluid (e.g., blood) in a vessel. In other embodiments, a catheter includes at least one inflatable balloon to selectively partially occlude a vessel to be imaged and/or treated in order to minimize the refractory effects of blood on the imaging/treatment process. In one embodiment, a catheter may image/treat at least a portion of a vessel by moving an imaging/treatment device in a distal direction relative to a proximal section of the catheter.

Abstract: A system for detecting tissue contact and penetration depth. The system comprises a needle sheath having a needle sheath inner diameter and a needle sheath outer diameter. A first conductive region is disposed on the needle sheath inner diameter. A needle having a needle insulation layer on the outer diameter upon which a second conductive region is disposed within the first conductive region. A dielectric layer is disposed between the first conductive tube and the second conductive tube. A capacitance sensor is coupled to the first conductive region and the second conductive region.

Abstract: A system for detecting tissue contact and penetration depth. The system comprises a needle sheath having a needle sheath inner diameter and a needle sheath outer diameter. A first conductive region is disposed on the needle sheath inner diameter. A needle having a needle insulation layer on the outer diameter upon which a second conductive region is disposed within the first conductive region. A dielectric layer is disposed between the first conductive tube and the second conductive tube. A capacitance sensor is coupled to the first conductive region and the second conductive region.

Abstract: A deflectable catheter assembly is disclosed. The assembly comprises a catheter shaft having a catheter proximal section and a catheter distal section, and at least one lumen extending therethrough. The catheter distal section is more flexible than the catheter proximal section. A tendon is disposed within a first lumen of said catheter shaft. The first lumen is approximately centrally located within the catheter shaft at the catheter proximal section. The first lumen is located off-center of the catheter shaft at the catheter distal section. The tendon is able to deflect the catheter distal section when being pulled on. A catheter handle is coupled to the catheter shaft at the catheter proximal section, the catheter handle includes a control mechanism to control the tendon.

Abstract: Systems and methods for determining tissue contact and penetration depth are provided. In one aspect, the system includes a needle and a pressure measurement assembly. The needle, in one exemplary embodiment, includes a first end and a second end with at least one aperture located a predetermined distance from the first end. The pressure measurement assembly is connected with a portion of the needle to measure pressure of fluid flowing through the needle. The pressure measurement assembly measures a first pressure when the needle contacts tissue and a second difference in pressure when the needle penetrates the tissue and the aperture becomes occluded. In an alternative aspect, the system includes a needle and a sensor. The sensor, in another exemplary embodiment, is coupled with a portion of the needle to detect tissue contact pressure on the sensor as the needle penetrates tissue and makes contact with the sensor. The sensor is located a predetermined distance from the first end of the needle.

Abstract: Systems and methods for determining tissue contact and penetration depth are provided. In one aspect, the system includes a needle and a pressure measurement assembly. The needle, in one exemplary embodiment, includes a first end and a second end with at least one aperture located a predetermined distance from the first end. The fluid pressure measurement assembly is connected with a portion of the needle to measure pressure of fluid dispensed in the needle. The fluid pressure measurement assembly measures a first pressure of the fluid, a second pressure when the needle contacts tissue and a third pressure when the needle penetrates the tissue and the aperture becomes occluded.

Abstract: A lead frame assembly includes one or more lead frames each defining a plurality of package locations organized in rows and columns. An injection molding system includes a plurality of culls, each cull being connected to the frame(s) through a plurality of subrunners. Each subrunner delivers molding compound from one of the culls to a respective column of package locations. A plurality of through gates are disposed between adjacent package locations within each column, each through gate supplying molding compound from one package location to a next adjacent package location within the column, each package location being filled with molding compound in turn from the preceding package location. The need for subrunners between adjacent columns of package locations is eliminated, allowing a higher density of package locations within the lead frame(s), reducing materials and labor costs, and increasing manufacturing productivity.

Abstract: A lead frame assembly includes one or more lead frames each defining a plurality of package locations organized in rows and columns. An injection molding system includes a plurality of culls, each cull being connected to the frame(s) through a plurality of subrunners. Each subrunner delivers molding compound from one of the culls to a respective column of package locations. A plurality of through gates are disposed between adjacent package locations within each column, each through gate supplying molding compound from one package location to a next adjacent package location within the column, each package location being filled with molding compound in turn from the preceding package location. The need for subrunners between adjacent columns of package locations is eliminated, allowing a higher density of package locations within the lead frame(s), reducing materials and labor costs, and increasing manufacturing productivity.