Patents by Inventor Dah-Shyong Yu

Dah-Shyong Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiochromeno[2,3-]quinolin-12-one derivatives, preparation method and application thereof
    Patent number: 8927717
    Abstract: The invention provides a series of novel thiochromeno[2,3-c]quinolin-12-one derivatives. Further, the invention also provides the preparation method and application of said derivatives, said application comprises: said derivatives with treating effective amount are prepared into pharmaceutical compositions for inhibition of topoisomerase type I and II, inhibition of cancer cell growth, further treating cancer.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: January 6, 2015
    Assignee: National Defense Medical Center
    Inventors: Hsu-Shan Huang, Dah-Shyong Yu, Tsung-Chih Chen
  • DNA cancer vaccines
    Patent number: 7605139
    Abstract: A plurality of DNA cancer vaccines and their uses in treating cancer are disclosed. Genes encoding Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) recombinant antigens and genes encoding interleukin-12 heterodimer were respectively cloned into eukaryotic expression vectors to express the encoded recombinant proteins in mammalian cells in vivo whereby specific immune responses are evoked and are effective in preventing, attenuating and/or suppressing the growth of a tumor.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: October 20, 2009
    Assignee: National Defense Medical Center
    Inventors: Dah-Shyong Yu, Sun-Yran Chang, Chi-Feng Lee
  • DNA cancer vaccines
    Publication number: 20060189556
    Abstract: A plurality of DNA cancer vaccines and their uses in treating cancer are disclosed. Genes encoding Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) recombinant antigens and genes encoding interlukin-12 heterodimer were respectively cloned into eukaryotic expression vectors to express the encoded recombinant proteins in mammalian cells in vivo whereby specific immune responses are evoked and are effective in preventing, attenuating and/or suppressing the growth of a tumor.
    Type: Application
    Filed: February 24, 2005
    Publication date: August 24, 2006
    Inventors: Dah-Shyong Yu, Sun-Yran Chang, Chi-Feng Lee