Patents by Inventor Dahlia ALKEKHIA

Dahlia ALKEKHIA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromogenic beta-lactamase substrate
    Patent number: 11957690
    Abstract: The invention provides a chromogenic ?-lactam molecule that retains its diagnostic color change response when modified for conjugation to another molecule.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: April 16, 2024
    Assignee: BROWN UNIVERSITY
    Inventors: Anita Shukla, Dahlia Alkekhia, Shashank Shukla, Hannah Safford
  • BACTERIAL BETA-LACTAMASE RESPONSIVE HYDROGELS
    Publication number: 20230029034
    Abstract: The invention provides a “host-guest” supramolecular hydrogel. The hydrogel contains an AAm/NVP interpenetrating polymer network (IPN) with supramolecular cross-linkers assembled from ?-lactam/adamantane-containing guest molecule with host polymeric cyclodextrin (PCD). An advantage of this hydrogel is that because of the molecular association of polymeric cyclodextrin and adamantane, the supramolecular hydrogels self-heal without any external stimuli after the hydrogels are severed. The invention also provides methods of making the hydrogel, methods of making the synthesis intermediates, and methods of diagnosis or treatment of ?-lactamase-containing bacteria.
    Type: Application
    Filed: October 28, 2020
    Publication date: January 26, 2023
    Inventors: Anita SHUKLA, Dahlia ALKEKHIA, Chao YU
  • A CHROMOGENIC BETA-LACTAMASE SUBSTRATE
    Publication number: 20210252010
    Abstract: The invention provides a chromogenic ?-lactam molecule that retains its diagnostic color change response when modified for conjugation to another molecule.
    Type: Application
    Filed: July 15, 2019
    Publication date: August 19, 2021
    Inventors: Anita SHUKLA, Dahlia ALKEKHIA, Shashank SHUKLA, Hannah SAFFORD