Abstract: The measurement of aluminum concentration is accomplished in high sensitivity with HPLC apparatus spread among the quality control divisions of pharmaceutical companies.

Abstract: A sample introducing device, placed in the midway of an analyzing apparatus having a sample flowing route and a carrier fluid flowing route, in which device a valve disc rotatably disposed under urging force between a pair of supporting members, provided with a sample flowing passage and a carrier fluid flowing passage, in a sandwiched manner, is manually rotated with a handle so as to switch a sample flowing hole made in the valve disc for containing a predetermined amount of a sample to a position alignable with the carrier fluid flowing passage. By this simple operation of rotating the valve disc the desired amount of the sample can be transferred to the carrier fluid flowing passage, through the switching over of the sample flowing hole, for being flowed to an apparatus for analysis.

Abstract: An open tubular capillary column, for high-speed micro liquid chromatography made of a glass tube of the inner diameter not more than 0.10 mm, having the net inside capacity not less than 0.5 .mu.l, the inner surface of which hollow glass tube being chemically bonded, in order to provide a stationary phase there, with at least one silane or its derivative such as octadecylsilane to form a polymeric layer. This invention includes the manufacturing method of such a column.