Patents by Inventor Daiji Iwata

Daiji Iwata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzimidazole derivatives
    Patent number: 5852011
    Abstract: Disclosed are compounds represented by the following chemical formula (I) and pharmacologically acceptable salts thereof which are novel compounds useful as anticancer agents, antiviral agents or antimicrobial agents.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: December 22, 1998
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Akio Matsunaga, Yuki Nakajima, Hiroshi Kohno, Hironori Komatsu, Hajime Edatsugi, Daiji Iwata, Kimiko Takezawa
  • Phenylbenzimidazole derivatives
    Patent number: 5821258
    Abstract: Described herein is an anticancer agent, an antiviral agent or an antimicrobial agent which contains, as an active ingredient for acting on DNA, a compound presented by the following formula (1) or its pharmacologically acceptable salt: ##STR1##
    Type: Grant
    Filed: December 22, 1995
    Date of Patent: October 13, 1998
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Akio Matsunaga, Yuki Nakajima, Hiroshi Kohno, Hiroshi Ohkouchi, Daiji Iwata, Hajime Edatsugi
  • Sulfonium salts of pyrrolylbenzimidazoles
    Patent number: 5808087
    Abstract: Compounds of formula (1): ##STR1## wherein m is an integer 1, 2 or 3,R.sub.1 and R.sub.2 are the same or independently different alkyl groups, each having 1-5 carbon atoms,R.sub.3 is a hydrogen atom, alkyl group having 1-3 carbon atoms, alkoxy group having 1-3 carbon atoms or halogen atom, andX.sup.- is an acid residue of acid selected from a group consisting of methanesulfonic acid, benzenesulfonic acid, toluenesulfonic acid and trifluoromethanesulfonic acid, and their salts are useful as an effective component of anticancer agents.
    Type: Grant
    Filed: November 25, 1996
    Date of Patent: September 15, 1998
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Akio Matsunaga, Yuki Mita, Hiroshi Kohno, Hajime Edatsugi, Daiji Iwata
  • Anti-asialo-GM1 monoclonal antibodies and method of use
    Patent number: 5443957
    Abstract: A monoclonal antibody which reacts with glycolipid asialo GM1 but not with any of glycolipids GM1 and GM2 can be produced by hybridoma cells obtained by fusing antibody-producing cells of a mammal immunized with the glycolipid asialo GM1 with myeloma cells.
    Type: Grant
    Filed: April 8, 1994
    Date of Patent: August 22, 1995
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Shizio Shimada, Tadashi Sudo, Daiji Iwata
  • Quinoline derivative fumarates
    Patent number: 5434155
    Abstract: Compounds having an activity to stimulate the carcinostatic effect of carcinostatic agents, which can be expressed by the following general formula (1): ##STR1## in which A is ##STR2## (in which R.sub.1, R.sub.2 and R.sub.3 are each independent and represent a hydrogen atom or a phenyl group) are made into fumarates so as to improve their oral absorbability and solubility in water without interfering with their effects.
    Type: Grant
    Filed: June 15, 1993
    Date of Patent: July 18, 1995
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Nobuyuki Fukazawa, Tuneji Suzuki, Kengo Otsuka, Osamu Yano, Daiji Iwata, Yukichi Kawai
  • Anti-ganglioside GD.sub.1 A monoclonal antibody MZ, MZ-producing cells and MZ-containing reagent
    Patent number: 5192662
    Abstract: Disclosed is a novel anti-ganglioside GD.sub.1a monoclonal antibody (MZ) which is capable of recognizing ganglioside GD.sub.1a but is practically incapable of recognizing GalCer, LacCer, Gb.sub.3, Gb.sub.4, GA.sub.1, GA.sub.2, GM.sub.2, GM.sub.3, GD.sub.1b, GT.sub.1b, GQ.sub.1b, Fuc-GM.sub.1, nLc.sub.4 and sialosyl nLc.sub.4 ; MZ-producing cells; an MZ-containing reagent; and a method for the detection or quantification of GD.sub.1a using the reagent, e.g., to diagnose cancer, systematic lupus erythematosus and diseases resulting from organic injury of the nervous system.
    Type: Grant
    Filed: September 7, 1988
    Date of Patent: March 9, 1993
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Shizuo Shimada, Daiji Iwata, Wakao Sato