Patents by Inventor Daiki Ninomiya

Daiki Ninomiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7087422
    Abstract: The object of the present invention is to provide Koji mold aminopeptidases capable of efficiently hydrolyzing persistent peptides and also genes encoding the aminopeptidases. The present invention provides Aspergillus nidulans aminopeptidase and nucleic acid molecules encoding it. In particular, the present invention provides a protein having an amino acid sequence represented by amino acid Nos. 1 to 519 in SEQ ID NO: 2, or a protein containing the substitution, deletion, insertion, addition or inversion of one or more amino acids in said sequence, and which protein has an activity of catalyzing the reaction for releasing an amino acid at an N-terminal of a peptide, and nucleic acid molecules encoding them.
    Type: Grant
    Filed: September 22, 2003
    Date of Patent: August 8, 2006
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kyoko Koibuchi, Daiki Ninomiya, Mari Kojima, Yoichi Ueda, Jun-ichi Maruyama, Katsuhiko Kitamoto
  • Publication number: 20040219636
    Abstract: The object of the present invention is to provide Koji mold aminopeptidases capable of efficiently hydrolyzing persistent peptides and also genes encoding the aminopeptidases. The present invention provides Aspergillus nidulans aminopeptidase and nucleic acid molecules encoding it. In particular, the present invention provides a protein having an amino acid sequence represented by amino acid Nos. 1 to 519 in SEQ ID NO: 2, or a protein containing the substitution, deletion, insertion, addition or inversion of one or more amino acids in said sequence, and which protein has an activity of catalyzing the reaction for releasing an amino acid at an N-terminal of a peptide, and nucleic acid molecules encoding them.
    Type: Application
    Filed: September 22, 2003
    Publication date: November 4, 2004
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kyoko Koibuchi, Daiki Ninomiya, Mari Kojima, Yoichi Ueda, Jun-ichi Maruyama, Katsuhiko Kitamoto
  • Publication number: 20040166200
    Abstract: The present invention relates to an amino acid composition. More specifically, the present invention provides an amino acid composition obtained by hydrolyzing proteinaceous koji containing soybean protein as the main raw material to release at least 65% of amino acids contained in the protein. The present invention further provides a process of producing the amino acid composition.
    Type: Application
    Filed: December 9, 2003
    Publication date: August 26, 2004
    Applicant: Ajinomoto Co., Inc.
    Inventors: Daiki Ninomiya, Kyoko Koibuchi, Sachi Hirai, Hideki Okamura, Naoko Tanaka
  • Patent number: 6303359
    Abstract: Disclosed are cDNA encoding a new aminopeptidase derived from germinated soybeans, a recombinant expression vector containing the DNA, a transformant obtained by the transformation with the expression vector, and a method of producing an aminopeptidase by culturing the transformed product. According to the present invention, a cDNA can be obtained encoding the amino acid sequence of aminopeptidase GX suitable for producing a highly hydrolized product from a starting material containing a protein and peptide having a high acidic amino acid content. Using the cDNA, a recombinant aminopeptidase can be mass-produced with E. coli or the like. By using the cDNA, it is also possible to produce aminopeptidase GX by using a host other than E. coli. In addition, hydrohized products having high glutamic acid content and aspartic acid content and also excellent seasoning properties can be obtained from soybean protein by combining GX thus produced with protease D3 and leucine aminopeptidase DLAP.
    Type: Grant
    Filed: March 14, 2000
    Date of Patent: October 16, 2001
    Assignee: Ajinomoto Co., Inc.
    Inventors: Daiki Ninomiya, Tetsuya Miwa, Minao Asano, Nami Nakamura, Noriki Nio