Patents by Inventor Daiming FAN

Daiming FAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene composition for detecting cell proliferative abnormality or grading disease degree and use thereof
    Patent number: 11840739
    Abstract: The present invention provides a composition, a kit and the use thereof, as well as the method for detecting the cell proliferative abnormality in individuals or grading the disease degree in the individuals. The composition comprises nucleic acids for detecting the methylation level within at least one target region of a gene and the fragment thereof.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: December 12, 2023
    Assignee: Biochain(Beijing) Science & Technology, Inc.
    Inventors: Xiaoliang Han, Tong Lu, Kaichun Wu, Yongzhan Nie, Daiming Fan, James Jianming Wang
  • Single-chain antibody specifically binding MG7, highly glycosylated CEA and use thereof in detection and therapy
    Patent number: 11266688
    Abstract: The present invention provides a glycosylated CEA-specific single-chain antibody, and a chimeric antigen receptor (CAR) targeting a glycosylated CEA, which can be used in manufacture of an agent or a medicament for diagnosis or treatment of a tumor overexpressing glycosylated CEA.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: March 8, 2022
    Assignees: THE FOURTH MILITARY MEDICAL UNIVERSITY XI'AN, SHANGHAI GENBASE BIOTECH CO., LTD.
    Inventors: Daiming Fan, Yongzhan Nie, Kaichun Wu, Yueqiong Cao, Jijun Yuan, Xuejun Yu
  • GENE COMPOSITION FOR DETECTING CELL PROLIFERATIVE ABNORMALITY OR GRADING DISEASE DEGREE AND USE THEREOF
    Publication number: 20210292847
    Abstract: The present invention provides a composition, a kit and the use thereof, as well as the method for detecting the cell proliferative abnormality in individuals or grading the disease degree in the individuals. The composition comprises nucleic acids for detecting the methylation level within at least one target region of a gene and the fragment thereof.
    Type: Application
    Filed: April 2, 2021
    Publication date: September 23, 2021
    Inventors: Xiaoliang Han, Tong Lu, Kaichun Wu, Yongzhan Nie, Daiming Fan, James Jianming Wang
  • SINGLE-CHAIN ANTIBODY SPECIFICALLY BINDING MG7, HIGHLY GLYCOSYLATED CEA AND USE THEREOF IN DETECTION AND THERAPY
    Publication number: 20190167721
    Abstract: The present invention provides a glycosylated CEA-specific single-chain antibody, and a chimeric antigen receptor (CAR) targeting a glycosylated CEA, which can be used in manufacture of an agent or a medicament for diagnosis or treatment of a tumor overexpressing glycosylated CEA.
    Type: Application
    Filed: July 27, 2017
    Publication date: June 6, 2019
    Inventors: Daiming FAN, Yongzhan NIE, Kaichun WU, Yueqiong CAO, Jijun YUAN, Xuejun YU