Patents by Inventor Daisuke ARINOBU

Daisuke ARINOBU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification method of virus-like particles
    Patent number: 10023844
    Abstract: The present invention aims at establishing a novel means for purifying norovirus VLPs. There is provided a purification method of norovirus virus-like particles, comprising: contacting solution containing norovirus virus-like particles with support for hydroxyapatite chromatography, binding the virus-like particles to the support, subsequently washing the support with buffer, and then eluting the virus-like particles from the support with buffer containing phosphate, wherein the phosphate concentration of the buffer used for elution is less than 10 mM.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: July 17, 2018
    Assignees: UMN PHARMA INC.
    Inventors: Masahiro Okada, Akiko Mukai, Tomonori Nishino, Daisuke Arinobu, Hiroyuki Ito, Mamoru Satoh
  • PRODUCTION METHOD FOR CULTURE CONTAINING VIRUS-LIKE PARTICLES
    Publication number: 20160215271
    Abstract: The present invention aims at establishing a means for obtaining highly pure virus-like particles by a simple method. There is provided a production method for culture containing virus-like particles, comprising: transforming insect cells with baculovirus vector containing a viral nucleic acid sequence; and cultivating the insect cells, wherein the culture is obtained after continuing cultivating the insect cells until the viability of the insect cells reaches 10% or less.
    Type: Application
    Filed: May 21, 2014
    Publication date: July 28, 2016
    Applicants: UMN PHARMA INC.
    Inventors: Masahiro OKADA, Akiko MUKAI, Tomonori NISHINO, Daisuke ARINOBU, Hiroyuki TO, Mamoru SATOH
  • PURIFICATION METHOD FOR VIRUS-LIKE PARTICLES
    Publication number: 20160168543
    Abstract: The present invention aims at establishing a novel means for purifying norovirus VLPs. There is provided a purification method of norovirus virus-like particles, comprising: contacting solution containing norovirus virus-like particles with support for hydroxyapatite chromatography, binding the virus-like particles to the support, subsequently washing the support with buffer, and then eluting the virus-like particles from the support with buffer containing phosphate, wherein the phosphate concentration of the buffer used for elution is less than 10 mM.
    Type: Application
    Filed: May 21, 2014
    Publication date: June 16, 2016
    Applicants: UMN PHARMA INC.
    Inventors: Masahiro OKADA, Akiko MUKAI, Tomonori NISHINO, Daisuke ARINOBU, Hiroyuki TO, Mamoru SATOH