Abstract: Provided is a compound superior in an ATX inhibitory action and useful for the prophylaxis or treatment of diseases involving ATX. A carboxylic acid compound represented by the following formula (1) or a pharmacologically acceptable salt thereof: wherein each symbol is as defined in the SPECIFICATION.

Abstract: Disclosed herein are liquid pharmaceutical formulations comprising levodopa amino acid conjugates that may further comprise a decarboxylase inhibitor, such as carbidopa, an antioxidant, a solvent, or any other pharmaceutically acceptable excipient. Further disclosed are methods of treating generative conditions and/or conditions characterized by reduced levels of dopamine in the brain, such as Parkinson's disease, comprising administering the disclosed liquid pharmaceutical formulations. Disclosed also are LDAA conjugate compounds.

Abstract: An inverter device includes first and second input terminals, a series circuit having a plurality of switch elements coupled between the first and second input terminals. Each of the switch elements is coupled in parallel with a series circuit having a diode and an inductor.

Abstract: Provided are a novel compound having a superior inhibitory action on KAT-II, a production method thereof, use thereof, and a pharmaceutical composition containing the aforementioned compound and the like. A compound represented by the formula (I) or a pharmacologically acceptable salt thereof. wherein each symbol is as defined in the DESCRIPTION.

Abstract: Provided are a novel compound having a superior inhibitory action on KAT-II, a production method thereof, use thereof, and a pharmaceutical composition containing the aforementioned compound and the like. A compound represented by the formula (I) or a pharmacologically acceptable salt thereof. wherein each symbol is as defined in the DESCRIPTION.

Abstract: The present invention provides a novel bicyclic or tricyclic heterocyclic compound represented by the formula (I) wherein ring A is an optionally substituted aromatic group, one of X1 and X2 is a carbon atom, and the other is a nitrogen atom, X3 is a nitrogen atom, or CR2, X4 is a nitrogen atom, or CR3, X5 is a sulfur atom, or —CH?CH—, Z1 is an oxygen atom, —C(R6)(R7)—, —NH—, —C(R6)(R7)—NH—, —NH—C(R6)(R7)—, —C(R6)(R7)—O—, —O—C(R6)(R7)—, or a single bond, one of Z2 and Z3 is CH and the other is a nitrogen atom, or both are nitrogen atoms, and other symbols are as defined in the DESCRIPTION, or a pharmacologically acceptable salt thereof.

Abstract: A method of detecting a fault of a semiconductor device including a power device mounted on a metal base and a drive circuit for driving the power device, the method detecting a fault of the semiconductor device beforehand based on an increase in thermal resistance between the metal base and the power device. A state of the power device is measured immediately before and after the power device is driven by the drive circuit. A temperature difference of the power device before and after driving is calculated according to the result of measurement. An increase in thermal resistance between the metal base and the power device is detected based on the temperature difference and an amount of electricity inputted to the power device in the driving period, and a fault of the semiconductor device is detected beforehand according to the increase.

Abstract: Provided is a compound superior in an autotaxin inhibitory action and the like, effective as a prophylactic or therapeutic drug for diseases involving ATX. The present invention relates to a compound represented by the following formula (I): [wherein each symbol is as described in the DESCRIPTION], which has a superior autotaxin inhibitory action and is useful as a prophylactic or therapeutic drug for diseases involving ATX.

Abstract: Switching loss is reduced by decreasing the switching frequency of a PFC power supply in light load condition, whereas the switching frequency is maintained high in heavy load operation. Efficiency in light load operation is thus improved without enlarging a boosting inductor and an output smoothing capacitor. A capacitor is provided in a triangular wave generating circuit and the triangular wave generating circuit outputs a triangular wave by charging and discharging this capacitor. Charging and discharging of the capacitor are controlled by an oscillation frequency control circuit output current which is input to a comparator.

Abstract: Provided is a compound superior in an autotaxin inhibitory action and the like, effective as a prophylactic or therapeutic drug for diseases involving ATX. The present invention relates to a compound represented by the following formula (I): [wherein each symbol is as described in the DESCRIPTION], which has a superior autotaxin inhibitory action and is useful as a prophylactic or therapeutic drug for diseases involving ATX.

Abstract: An obtained margin is smaller than a margin to be kept for a fault period predicted by life prediction based on a power cycle test, extending a maintenance cycle for replacement and so on. A method of detecting a fault of a semiconductor device including a power device mounted on a metal base and a drive circuit for driving the power device, the method detecting a fault of the semiconductor device beforehand based on an increase in thermal resistance between the metal base and the power device. A state of the power device is measured immediately before and after the power device is driven by the drive circuit. A temperature difference of the power device before and after driving is calculated according to the result of measurement.

Abstract: The present invention provides a novel bicyclic or tricyclic heterocyclic compound represented by the formula (I) wherein ring A is an optionally substituted aromatic group, one of X1 and X2 is a carbon atom, and the other is a nitrogen atom, X3 is a nitrogen atom, or CR2, X4 is a nitrogen atom, or CR3, X5 is a sulfur atom, or —CH?CH—, Z1 is an oxygen atom, —C(R6)(R7)—, —NH—, —C(R6)(R7)—NH—, —NH—C(R6)(R7)—, —C(R6)(R7)—O—, —O—C(R6)(R7)—, or a single bond, one of Z2 and Z3 is CH and the other is a nitrogen atom, or both are nitrogen atoms, and other symbols are as defined in the DESCRIPTION, or a pharmacologically acceptable salt thereof.

Abstract: Switching loss is reduced by decreasing the switching frequency of a PFC power supply in light load condition, whereas the switching frequency is maintained high in heavy load operation. Efficiency in light load operation is thus improved without enlarging a boosting inductor and an output smoothing capacitor. A capacitor is provided in a triangular wave generating circuit and the triangular wave generating circuit outputs a triangular wave by charging and discharging this capacitor. Charging and discharging of the capacitor are controlled by an oscillation frequency control circuit output current which is input to a comparator.

Abstract: Switching loss is reduced by decreasing the switching frequency of a PFC power supply in light load condition, whereas the switching frequency is maintained high in heavy load operation. Efficiency in light load operation is thus improved without enlarging a boosting inductor and an output smoothing capacitor. A capacitor is provided in a triangular wave generating circuit and the triangular wave generating circuit outputs a triangular wave by charging and discharging this capacitor. Charging and discharging of the capacitor are controlled by an oscillation frequency control circuit output current which is input to a comparator.

Abstract: Switching loss is reduced by decreasing the switching frequency of a PFC power supply in light load condition, whereas the switching frequency is maintained high in heavy load operation. Efficiency in light load operation is thus improved without enlarging a boosting inductor and an output smoothing capacitor. A capacitor is provided in a triangular wave generating circuit and the triangular wave generating circuit outputs a triangular wave by charging and discharging this capacitor. Charging and discharging of the capacitor are controlled by an oscillation frequency control circuit output current which is input to a comparator.

Abstract: The present invention provides a method of improving efficiency in a full load region in a PFC power source of an active filter method by controlling a switch circuit of the PFC power source in association with an output power of the PFC power source. A pair of two switches controlling charging/discharging an inductor is provided. A MOSFET switch having a small current capacity is used as one of the switches, and an IGBT switch of a large current capacity is used as the other switch. When an output of a voltage dividing circuit for dividing voltage of an output terminal of the PFC power source is smaller than a threshold voltage, only the MOSFET switch is operated. When the output exceeds a threshold voltage, the IGBT switch is also operated.