Abstract: A charge port device includes a charge port provided in a port accommodation recess and a lid for concealing the port accommodation recess. A latch is provided in the port accommodation recess on an opposite side to a lid hinge with respect to the charge port. A slit is formed between a surface of a vehicle body and an outer circumferential edge of the lid while the lid is closed. A lamp is provided at a position in the port accommodation recess between the latch and the slit on an opposite side to the lid hinge with respect to the charge port and the position is not visible from outside while the lid is closed. Formed is a light-guiding reflection path that guides a light emitted from the lamp toward the above-mentioned slit as an indirect light by reflecting the light while the lid is closed.

Abstract: The present disclosure provides a measurement method of telomerase activity with no occurrence of false-negative and high quantitative capability. In the measurement method of telomerase activity of the present disclosure, a solution containing telomerase as a sample solution is mixed with a solution containing primer DNA as a substrate for telomerase even as or after a solution containing non-primer DNA not as a substrate for telomerase is mixed therewith. Non-primer DNA can remove an effect of DNase in the sample solution and prevent occurrence of false-negative. Subsequently, the primer DNA is extended with the telomerase and the extended primer DNA is detected, through which telomerase activity is measured.

Abstract: The present disclosure provides a measurement method of telomerase activity with no occurrence of false-negative and high quantitative capability. In the measurement method of telomerase activity of the present disclosure, a solution containing telomerase as a sample solution is mixed with a solution containing primer DNA as a substrate for telomerase even as or after a solution containing non-primer DNA not as a substrate for telomerase is mixed therewith. Non-primer DNA can remove an effect of DNase in the sample solution and prevent occurrence of false-negative. Subsequently, the primer DNA is extended with the telomerase and the extended primer DNA is detected, through which telomerase activity is measured.

Abstract: The method of the present disclosure determines whether a target DNA forms a G-quadruplex using a phenomenon in which thioflavin T generates a strong fluorescence when reacted with the G-quadruplex in the presence of potassium ions.

Abstract: The present invention provides a method for obtaining an aqueous solution where divalent metal cations, a phthalocyanine compound modified with an anionic functional group, and G-quadruplex are dissolved, the method comprising step of: mixing the divalent metal cations, the phthalocyanine compound modified with the anionic functional group, and the G-quadruplex into water so as to dissolve the phthalocyanine compound in the water.

Abstract: It is an object of the method of the present invention to specifically detect a G-quadruplex even in the presence of potassium ions. The method of the present invention determines whether a target DNA forms a G-quadruplex using a phenomenon in which thioflavin T generates a strong fluorescence when reacted with the G-quadruplex in the presence of potassium ions. In the method of the present invention, a first sample solution containing potassium ions and a target DNA is retained under such conditions that a G-quadruplex is formed, followed by adding thioflavin T and measuring a first fluorescence intensity value. A second sample solution containing the target DNA is retained under conditions for the G-quadruplex to be destabilized, thioflavin T is added, a second fluorescence intensity value is measured, and it is determined that the target DNA can form a G-quadruplex if a difference between the first fluorescence intensity value and the second fluorescence intensity value is 0 or more.

Abstract: A method is provided for specifically detecting a G-quadruplex, and the like. The method is characterized by including the steps of preparing a solution including an anionic planar phthalocyanine and mixing the solution with a sample solution to obtain a liquid mixture. The solution includes an anionic planar phthalocyanine. The method also includes a step of measuring the absorbance at 640 to 740 nm of the obtained liquid mixture.

Abstract: A method is provided for specifically detecting a G-quadruplex, and the like. The method is characterized by including the steps of preparing a solution including an anionic planar phthalocyanine and mixing the solution with a sample solution to obtain a liquid mixture. The solution includes an anionic planar phthalocyanine. The method also includes a step of measuring the absorbance at 640 to 740 nm of the obtained liquid mixture.

Abstract: A method is provided for specifically detecting a G-quadruplex, and the like. The method is characterized by including the steps of preparing a solution including an anionic planar phthalocyanine and mixing the solution with a sample solution to obtain a liquid mixture. The solution includes an anionic planar phthalocyanine. The method also includes a step of measuring the absorbance at 640 to 740 nm of the obtained liquid mixture.

Abstract: An object of the present invention is to provide a method for inhibiting a DNA extension reaction by telomerase. More specifically, the present invention relates to a method for inhibiting a DNA extension reaction by telomerase, the method being characterized by including the step of adding an anionic phthalocyanine to a solution containing telomerase, a DNA to be a substrate of a telomerase reaction, and dNTPs.

Abstract: An object of the present invention is to provide a method for inhibiting a DNA extension reaction by telomerase. More specifically, the present invention relates to a method for inhibiting a DNA extension reaction by telomerase, the method being characterized by including the step of adding an anionic phthalocyanine to a solution containing telomerase, a DNA to be a substrate of a telomerase reaction, and dNTPs.

Abstract: The present invention provides a method for specifically detecting a G-quadruplex, and the like. The method for detecting a G-quadruplex of the present invention is characterized by including the steps of: (a) preparing a solution including an anionic planar phthalocyanine; (b) mixing the solution including an anionic planar phthalocyanine with the sample solution; and (c) measuring the absorbance at 640 to 740 nm of a liquid mixture obtained following the step (b).

Abstract: The present invention provides a method of producing a DNA structure in which multiple quadruplex DNAs are linked, which includes (a) a step of mixing multiple DNA molecules having an antiparallel quadruplex structural part, and at least two single stranded sticky ends extended from the end of the quadruplex structural part, wherein the single stranded sticky end of the each DNA molecule has a base sequence that can form a duplex through interaction with the single stranded sticky end of other DNA molecule.

Abstract: A fluorescent probe having a base sequence complementary to a specific sequence in a target nucleic acid, wherein the fluorescent probe has one end labeled with a nano particle fluorescent material, and the other end labeled with a fluorescent dye capable of fluorescence resonance energy transfer from the nano particle fluorescent material.