Abstract: The present invention provides a nucleic acid construct for expressing an oxidative stress indicator comprising: a nucleic acid sequence encoding an Nrf2 protein-derived partial protein that comprises at least an Neh2 domain sequence and substantially lacks or is functionally deficient in an Neh1 domain sequence or an Neh1-Neh3 domain sequence; a stress-inducible promoter sequence positioned upstream of the nucleic acid sequence encoding an Nrf2 protein-derived partial protein; and a nucleic acid sequence encoding a protein capable of generating a detectable signal, the nucleic acid sequence being positioned downstream of the nucleic acid sequence encoding an Nrf2 protein-derived partial protein. The present invention also provides a method for measuring oxidative stress and a method for screening for an anti-oxidative stress agent, using the nucleic acid construct.

Abstract: The present invention provides a method for detection of an inflammatory reaction, which comprises using a transformant or transgenic non-human animal transfected with a vector comprising a promoter for a gene encoding an inflammatory cytokine, a gene encoding a reporter protein, a gene encoding the inflammatory cytokine, and a gene encoding a proteolytic signal sequence to thereby detect an inflammatory reaction induced upon inflammatory stimulation in the transformant or in the transgenic non-human animal.

Abstract: The present invention provides a method for detection of an inflammatory reaction, which comprises using a transformant or transgenic non-human animal transfected with a vector comprising a promoter for a gene encoding an inflammatory cytokine, a gene encoding a reporter protein, a gene encoding the inflammatory cytokine, and a gene encoding a proteolytic signal sequence to thereby detect an inflammatory reaction induced upon inflammatory stimulation in the transformant or in the transgenic non-human animal.

Abstract: In a case structure for a fluid pressure device, a filter that constitutes part of a fluid pressure unit is equipped with a first body, a case unit connected to a lower portion of the first body, and a filter unit accommodated in the interior of the case unit. The case unit is made up from an outer case, which is formed as a bottomed cylinder from a light-permeable transparent material, and an inner case inserted into the interior of the outer case. Additionally, by insertion of the case unit into an installation hole that opens on a lower portion of the first body and rotating the case unit, projections and retaining walls provided on an outer circumferential surface of the case unit engage with support members provided in the installation hole, thus placing the case unit in a connected state.

Abstract: A filter apparatus is equipped with a first body, a case unit connected to a lower part of the first body, and a filter unit, which is accommodated in the interior of the case unit. The case unit is made up from an outer case, which is formed as a bottomed cylinder from a light-permeable transparent material, and an inner case that is inserted into the interior of the outer case. The case unit is inserted into an installation hole that opens on the lower part of the first body, and by rotation thereof, projections and retaining walls provided on an outer circumferential surface of the case unit are made to engage with support members provided in the installation hole, to thereby result in a connected state.

Abstract: In a case structure for a fluid pressure device, a filter that constitutes part of a fluid pressure unit is equipped with a first body, a case unit connected to a lower portion of the first body, and a filter unit accommodated in the interior of the case unit. The case unit is made up from an outer case, which is formed as a bottomed cylinder from a light-permeable transparent material, and an inner case inserted into the interior of the outer case. Additionally, by insertion of the case unit into an installation hole that opens on a lower portion of the first body and rotating the case unit, projections and retaining walls provided on an outer circumferential surface of the case unit engage with support members provided in the installation hole, thus placing the case unit in a connected state.

Abstract: A filter apparatus (12) is equipped with a first body (20), a case unit (22) connected to a lower part of the first body (20), and a filter unit (24), which is accommodated in the interior of the case unit (22). The case unit (22) is made up from an outer case (40), which is formed as a bottomed cylinder from a light-permeable transparent material, and an inner case (42) that is inserted into the interior of the outer case (40). The case unit (22) is inserted into an installation hole (36) that opens on the lower part of the first body (20), and by rotation thereof, projections (58) and retaining walls (56) provided on an outer circumferential surface of the case unit (22) are made to engage with support members (38) provided in the installation hole (36), to thereby result in a connected state.

Abstract: The present invention provides a nucleic acid construct for expressing an oxidative stress indicator comprising: a nucleic acid sequence encoding an Nrf2 protein-derived partial protein that comprises at least an Neh2 domain sequence and substantially lacks or is functionally deficient in an Neh1 domain sequence or an Neh1-Neh3 domain sequence; a stress-inducible promoter sequence positioned upstream of the nucleic acid sequence encoding an Nrf2 protein-derived partial protein; and a nucleic acid sequence encoding a protein capable of generating a detectable signal, the nucleic acid sequence being positioned downstream of the nucleic acid sequence encoding an Nrf2 protein-derived partial protein. The present invention also provides a method for measuring oxidative stress and a method for screening for an anti-oxidative stress agent, using the nucleic acid construct.