Abstract: A positive electrode active material, which has a crystallite size ?/crystallite size ? ratio (?/?) of 1 to 1.75 or less, wherein the crystallite size ? is within a peak region of 2?=18.7±1° and the crystallite size ? is within a peak region of 2?=44.6±1°, each determined by a powder X-ray diffraction measurement using Cu-K? ray, and has a composition represented by formula (I) below: Li[Lix(NiaCobMncMd)1-x]O2??(I) wherein 0?x?0.2, 0.3<a<0.7, 0<b<0.4, 0<c<0.4, 0?d<0.1, a+b+c+d=1, and M is at least one metal selected from the group consisting of Fe, Cr, Ti, Mg, Al and Zr.

Abstract: A rolling bearing includes: an inner ring; an outer ring; and a plurality of rolling elements provided between the inner ring and the outer ring, wherein: one of the inner ring and the outer ring is a rotating ring; the other one of the inner ring and the outer ring is a firm ring; the firm ring is attached to a prescribed member; and a black oxide film having a mesh-shaped crack is formed on at least one surface of a fitting surface of the firm ring and a side face of the firm ring, the fitting surface facing the prescribed member in a radial direction of the rolling bearing, the side face making contact with the prescribed member in an axial direction of the rolling bearing.

Abstract: A toner comprising a toner particle including a binder resin and a crystalline polyester resin, wherein the binder resin is an amorphous polyester resin having a linear alkyl group at a molecular chain terminal; the crystalline polyester resin is a polycondensate of a diol and a dicarboxylic acid; the number of carbon atoms CaPES of the linear alkyl group, the number of carbon atoms COH of the diol, and the number of carbon atoms CAc of the dicarboxylic acid, excluding carbon that belongs to carboxyl groups, satisfy the following relationships; and a glass transition temperature of the toner as measured by a differential scanning calorimeter is from 40.0° C. to 55.0° C. 8?CaPES?20??(1) CAc/COH?3.5 and 0?|CAc?CaPES|?3??(2) COH/CAc?3.

Abstract: The position of a metal marker 5 relative to an optical fiber 6 is fixed, and the metal marker 5 can be moved up close to a target site such as a thrombus. It is preferable that the position, in an optical fiber longitudinal direction, of a front-end face of the optical fiber 6 is coincident with the position, in an optical fiber longitudinal direction, of a front-end face of the metal marker 5. More specifically, since the distance between the target site and the front end of the optical fiber 6 is known by radiography, it becomes unnecessary to use a large quantity of contrast agent and irradiate a laser beam depending on skill and intuition, and therefore an effective laser beam irradiation becomes possible.

Abstract: [Problem] To provide a compound useful as an MC4 receptor agonist. [Means for Solution] The present inventors studied MC4 receptor agonists, and have found that a piperazine derivative has an MC4 receptor agonistic action, thereby completing the present invention. The piperazine derivative of the present invention has an MC4 receptor agonistic action, and can be used as an agent for preventing or treating bladder and/or urinary tract diseases, in particular, underactive bladder, hypotonic bladder, acontractile bladder, detrusor underactivity, neurogenic bladder, urethral relaxation failure, detrusor-external urethral sphincter dyssynergia, and voiding dysfunctions in benign prostatic hyperplasia.

Abstract: A rolling bearing includes: an inner ring; an outer ring; and a plurality of rolling elements provided between the inner ring and the outer ring, wherein: one of the inner ring and the outer ring is a rotating ring; the other one of the inner ring and the outer ring is a firm ring; the firm ring is attached to a prescribed member; and a black oxide film having a mesh-shaped crack is formed on at least one surface of a fitting surface of the firm ring and a side face of the firm ring, the fitting surface facing the prescribed member in a radial direction of the rolling bearing, the side face making contact with the prescribed member in an axial direction of the rolling bearing.

Abstract: To provide a compound which can be used as an MC4 receptor agonist. The present inventors have investigated MC4 receptor agonists, and have found that a piperazine derivative has an action related to the agonists, thereby completing the present invention. That is, the piperazine derivative of the present invention has an MC4 receptor agonistic action, and can be used as an agent for preventing or treating bladder and/or urinary tract diseases, in particular, underactive bladder, hypotonic bladder, acontractile bladder, detrusor underactivity, neurogenic bladder, urethral relaxation failure, detrusor-external urethral sphincter dyssynergia, and voiding dysfunctions in benign prostatic hyperplasia.

Abstract: Provided is a positive electrode active material which is useful for a lithium secondary battery having a battery resistance lower than that of the conventional positive electrode active material below freezing point. The positive electrode active material for a lithium secondary battery contains at least one element selected from a group consisting of nickel, cobalt and manganese, the positive electrode active material having a layered structure and satisfying all of the following requirements (1) to (3): (1) a primary particle size is 0.1 ?m to 1 ?m and a secondary particle size is 1 ?m to 10 ?m; (2) in an X-ray powder diffraction measurement using CuK? radiation, a crystallite size in the peak within 2?=18.7±1° is 100 ? to 1200 ? and a crystallite size in the peak within 2?=44.6±1° is 100 ? to 700 ?; and (3) in a pore distribution obtained by a mercury intrusion method, a pore peak exists in a range where the pore size is 10 nm to 200 nm and a pore volume in the said range is 0.01 cm3/g to 0.05 cm3/g.

Abstract: A toner includes a toner particle containing a resin component containing an olefin copolymer, wherein the olefin copolymer includes a specific monomer unit Y1 and a specific monomer unit Y2, and the content of the olefin copolymer in the resin component is more than 50 mass % based on the total mass of the resin component, and the olefin copolymer has a melting point of 80° C. or more and 150° C. or less.

Abstract: A toner in which the content of polysiloxane is 1% by mass or more and 15% by mass or less based on the total mass of toner particles, the polysiloxane is present in the toner as a domain of 10 nm or more and 500 nm or less, and Siloxane index (Ge)/Siloxane index (D) of the toner particles is 1.0 or less.

Abstract: A toner comprising a toner particle that contains a hybrid resin A and a crystalline polyester resin B, wherein the hybrid resin A has a polyester segment, and a polypropylene glycol segment that has a number-average molecular weight of at least 300, the polyester segment has a structure derived from a condensation reaction between a dicarboxylic acid and a diol, and has an aromatic ring in at least one of the dicarboxylic acid and the diol, and the following condition is satisfied: |SPh?SPc|?|SPp?SPc|<1 where, SPh is SP value of the polyester segment of the hybrid resin A, SPc is SP value of the crystalline polyester resin B, and SPp is SP value of the polypropylene glycol segment of the hybrid resin A.

Abstract: A cell observation system observes a cell moving in a flow path with a fluid, and includes a first observation apparatus, a second observation apparatus, and a control device. The first observation apparatus includes an objective lens and a line camera. The second observation apparatus includes an objective lens and an area camera. The control device analyzes first imaging data output from the first observation apparatus to determine whether the cell satisfies a specific condition, instructs the area camera to output second imaging data of the cell determined to satisfy the specific condition, and analyzes the second imaging data output from the second observation apparatus to determine whether the cell is a specific cell.

Abstract: A method for producing a toner includes a step (1) of forming resin microparticles in an aqueous medium in the presence of a surfactant, a step (2) of aggregating the resin microparticles to form aggregated particles, and a step (3) of heating and the aggregated particles and allowing the aggregated particles to coalesce to form toner particles, in which a resin component in the resin microparticles contains an olefinic copolymer and resin A, the resin A has an acid value of 1 mgKOH/g or more and 50 mgKOH/g or less, the resin A has a SP value of 19.0 (J/cm3)0.5 or more and 21.0 (J/cm3)0.5 or less, and the resin component has an olefinic copolymer content of 50% by mass or more with respect to the total mass of the resin component.

Abstract: A toner including: a binder resin containing an ethylene-vinyl acetate copolymer; a polysiloxane derivative A represented by structural formula 1; and a polysiloxane derivative B represented by structural formula 2: (in structural formula 1, R1 to R10 each independently represent a methyl group or a phenyl group, and l, m and n each independently represent an integer of at least 1) (in structural formula 2, at least one of R11 to R20 is an organic group having a C4-30 alkyl group, a C4-30 alkoxy group, an acrylic group, an amino group, a methacrylic group or a carboxyl group, the remaining groups among R11 to R20 each independently represent a methyl group or a phenyl group, and p, q and r each independently represent an integer of at least 1).

Abstract: A method of reusing core sand includes: crushing a core used for casting into granules; heating the granules at a temperature of 300° C. to 550° C.; causing the heated granules to collide against each other such that water glass used as a binder detaches from the core sand; and blowing air into a mixture of the water glass and the core sand, which are detached from each other, such that the core sand is separated and collected from the mixture due to a difference in specific gravity between the water glass and the core sand.

Abstract: A positive electrode active material for lithium secondary batteries which is able to doped/undoped with lithium ions and contains at least Ni, in which a ratio P/Q (atom %/mass %) of a concentration P (atom %) of sulfur atoms being present in a surface of the positive electrode active material to a concentration Q (mass %) of sulfuric acid radicals being present in the whole positive electrode active material is more than 0.8 and less than 5.0, and the Q (mass %) is 0.01 or more and 2.0 or less.

Abstract: A toner comprising a toner particle including a resin component, wherein the resin component includes an olefin resin and an olefin copolymer including a hydroxyl group, the olefin resin has a specific monomer unit Y1, the olefin copolymer including a hydroxyl group has a specific monomer unit Z1 and Z2, a hydroxyl value of the olefin resin is not more than 10 mg KOH/g, a hydroxyl value of the olefin copolymer including a hydroxyl group is at least 20 mg KOH/g and not more than 250 mg KOH/g, and a content of the olefin resin in the resin component is more than 50 mass % with respect to a total mass of the resin component.

Abstract: A toner having a toner particle containing a resin component, wherein the resin component contains an olefin copolymer having ester group and the like, which has a unit (1), and a unit Y2 that is at least one selected from (2) and (3), the content of the copolymer in the resin component is at least 50 mass % with respect to the total mass of the resin component, and the content of the monomer unit Y2 is 3 to 35 mass % with respect to the total mass of the copolymer; in formulas (1) to (3), R1, R2 and R4 each independently represent H or CH3, and R3 and R5 each independently represent CH3 or C2H5.

Abstract: [Problem] To provide a compound which can be used as an MC4 receptor agonist. [Means for Solution] The present inventors have investigated MC4 receptor agonists, and have found that a piperazine derivative has an action related to the agonists, thereby completing the present invention. That is, the piperazine derivative of the present invention has an MC4 receptor agonistic action, and can be used as an agent for preventing or treating bladder and/or urinary tract diseases, in particular, underactive bladder, hypotonic bladder, acontractile bladder, detrusor underactivity, neurogenic bladder, urethral relaxation failure, detrusor-external urethral sphincter dyssynergia, and voiding dysfunctions in benign prostatic hyperplasia.

Abstract: A method of reusing core sand includes crushing a core used for casting into granules; heating the granules at a temperature of 300° C. to 550° C.; causing the heated granules to collide against each other such that water glass used as a binder detaches from the core sand; and blowing air into a mixture of the water glass and the core sand, which are detached from each other, such that the core sand is separated and collected from the mixture due to a difference in specific gravity between the water glass and the core sand.