Abstract: An antithrombotic compound of the formula: ##STR1## wherein R.sup.1 is halogen,R.sup.2 is lower alkylene andR.sup.3 is lower alkyl, hydroxy(lower)alkyl, acyloxy (lower)alkyl or acyl(lower)alkyl, andpharmaceutically acceptable salts thereof.

Abstract: Compounds of the formula ##STR1## are disclosed whereinR.sup.1 is hydrogen or lower alkyl, one of R.sup.2 and R.sup.3 is mono (or di)-nitroxy(lower)alkyl and the otherR.sup.2 and R.sup.3 is hydrogen and pharmaceutically acceptable salts thereof.Also disclosed are vasodilating compositions containing the above.

Abstract: The present invention relates to novel benzhydrylpiperazine derivatives having anti-allergic activities, the preparation of these derivatives, pharmaceutical compositions comprising the same, and to a method of using these compounds therapeutically in the treatment of allergic symptoms in human beings and animals.These benzhydrylpiperazine derivatives have the follow formula: ##STR1## wherein A is a lower alkylene, Z is a benzhydryl optionally substituted with halogen, andR.sup.1 is amino, aryl, pyridyl, acyl or acylamino, in which the aryl group and pyridyl group are substituted with nitro, amino or acyl amino groups, provided that Z is benzhydryl substituted with a halogen, when R.sup.1 is an amino group.

Abstract: The invention relates to novel dihydropyridine derivatives of vasodilating activity of the formula: ##STR1## in which R.sup.1 is aryl selected from the group consisting of phenyl, tolyl, xylyl, cumenyl and mesityl which may have one or more substituents selected from the group consisting of halogen, nitro, hydroxy, carboxy and lower alkoxy, or a heterocyclic group containing at least one hetero atom selected from the group consisting of oxygen, nitrogen and sulfur,R.sup.2 is lower alkoxy-carbonyl or N,N-disubstituted amino(lower)alkoxycarbonyl,R.sup.3 is lower alkyl, alkanoyl, protected alkanoyl or cyano,R.sup.4 is lower alkyl andA is lower alkylene, and pharmaceutically acceptable salt thereof.

Abstract: This invention relates to pyridylalkyl nitrate compound and a salt thereof. More particularly, it relates to a new pyridylalkyl nitrate compound and a pharmaceutically acceptable salt thereof which have vasodilating activities, to process for the preparation thereof, and to a pharmaceutical composition comprising the same for therapeutical treatment of cardiovascular disorder in human being.