Patents by Inventor Dake Tian

Dake Tian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Morpholinone and morpholine derivatives and uses thereof
    Publication number: 20030212062
    Abstract: This invention is directed to morpholinone and morpholine derivatives which are selective antagonists for human &agr;1a receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia, sympathetic mediated pain, migraine, and for the treatment of any disease where the antagonism of the &agr;1a receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: March 11, 2003
    Publication date: November 13, 2003
    Applicant: Synaptic Pharmaceutical Corporation
    Inventors: Bharat Lagu, Dhanapalan Nagarathnam, Dake Tian, Charles Gluchowski
  • Morpholinone and morpholine derivatives and uses thereof
    Patent number: 6531471
    Abstract: This invention is directed to morpholinone and morpholine derivatives which are selective antagonists for human &agr;1a receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia, sympathetic mediated pain, migraine, and for the treatment of any disease where the antagonism of the &agr;1a receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: December 14, 2001
    Date of Patent: March 11, 2003
    Assignee: Synaptic Pharmaceutical Corporation
    Inventors: Bharat Lagu, Dhanapalan Nagarathnam, Dake Tian, Charles Gluchowski
  • Morpholinone and morpholine derivatives and uses thereof
    Publication number: 20020068737
    Abstract: This invention is directed to morpholinone and morpholine derivatives which are selective antagonists for human &agr;1a receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia, sympathetic mediated pain, migraine, and for the treatment of any disease where the antagonism of the &agr;1a receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 14, 2001
    Publication date: June 6, 2002
    Applicant: Synaptic Pharamceutical Corporation
    Inventors: Bharat Lagu, Dhanapalan Nagarathnam, Dake Tian, Charles Gluchowski
  • Morpholinone and morpholine derivatives and uses thereof
    Patent number: 6362182
    Abstract: This invention is directed to morpholinone and morpholine derivatives which are selective antagonists for human &agr;1a receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia, sympathetic mediated pain, migraine, and for the treatment of any disease where the antagonism of the &agr;1a receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: October 30, 2000
    Date of Patent: March 26, 2002
    Assignee: Synaptic Pharmaceutical Corporation
    Inventors: Bharat Lagu, Dhanapalan Nagarathnam, Dake Tian, Charles Gluchowski
  • Morpholinone and morpholine derivatives and uses thereof
    Patent number: 6218390
    Abstract: This invention is directed to morpholinone and morpholine derivatives which are selective antagonists for human &agr;1a receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia, sympathetic mediated pain, migraine, and for the treatment of any disease where the antagonism of the &agr;1a receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: April 17, 2001
    Assignee: Synaptic Pharmaceutical Corporation
    Inventors: Bharat Lagu, Dhanapalan Nagarathnam, Dake Tian, Charles Gluchowski