Patents by Inventor Dale C. Harris
Dale C. Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5545147Abstract: The present invention provides an improved device for preventing the backing up of a nut on a threaded piston rod in the barrel of a hypodermic syringe at the end of dose administration from such syringe. The preferred device is a pawl mounted on the end of a flexible arm of a nut which cooperates with slots on the inside of a syringe barrel. The nut also has an incline surface at the end which mates with an incline surface in the barrel end. The mating of these surfaces at the end of dose administration forces the pawl into a slot, thereby preventing rotation of the nut in the wrong direction and the concurrent movement of the nut up the piston rod associated therewith.Type: GrantFiled: October 20, 1992Date of Patent: August 13, 1996Assignee: Eli Lilly and CompanyInventor: Dale C. Harris
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Patent number: 5454786Abstract: A cartridge assembly for holding a lyophilized product, forming a disposable portion of a pen injector includes a cylindrical glass cartridge adapted to receive the product, a closure cap, a cartridge case, and a plunger mechanism. The closure cap is adapted to retain an elastomeric disc seal during lyophilization and includes diametrically opposed ledges. The closure cap and seal are adapted to cover a neck portion of the ampule, the neck portion having on its end a radially extending circumferential flange. The ledges of the closure cap and the flange of the neck portion allow the closure cap to remain open during lyophilization, oxygen purge and nitrogen overlay. An oval-shaped indentation formed on the inside of the closure cap aids in snapping the closure cap about the flange without crimping to retain the closure cap underneath the flange.Type: GrantFiled: March 28, 1994Date of Patent: October 3, 1995Assignee: Eli Lilly and CompanyInventor: Dale C. Harris
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Patent number: 5391157Abstract: The present invention provides an improvement in injection syringes by providing for an end of dose indicator which is operatively associated with the dose knob of an injection syringe. The instant end of dose indicator works by providing a sound as an indication that the complete dose has been administered.Type: GrantFiled: October 20, 1992Date of Patent: February 21, 1995Assignee: Eli Lilly and CompanyInventors: Dale C. Harris, John S. Ploof
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Patent number: 5334162Abstract: A cartridge assembly for holding a lyophilized product, forming a disposable portion of a pen injector includes a cylindrical glass cartridge adapted to receive the product, a closure cap, a cartridge case, and a plunger mechanism. The closure cap is adapted to retain an elastomeric disc seal during lyophilization and includes diametrically opposed ledges. The closure cap and seal are adapted to cover a neck portion of the ampule, the neck portion having on its end a radially extending circumferential flange. The ledges of the closure cap and the flange of the neck portion allow the closure cap to remain open during lyophilization, oxygen purge and nitrogen overlay. An oval-shaped indentation formed on the inside of the closure cap aids in snapping the closure cap about the flange without crimping to retain the closure cap underneath the flange.Type: GrantFiled: March 15, 1993Date of Patent: August 2, 1994Assignee: Eli Lilly and CompanyInventor: Dale C. Harris
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Patent number: 5308340Abstract: The present invention relates to a hypodermic syringe having the same general appearance as a pen which is specifically adapted to provide for multiple measure injections of materials such as insulin or human growth hormone.Type: GrantFiled: June 17, 1993Date of Patent: May 3, 1994Assignee: Eli Lilly and CompanyInventor: Dale C. Harris
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Patent number: 5295976Abstract: Two embodiments of a multi-dose syringe both include structure for indicating the selected amount of liquid to be injected. A first element and a second element coupled respectively to the syringe housing and the plunger rod are adapted for calibrated movement with respect to each other, one of the first and second elements includes an outer portion having dose-indicating scale thereon, and another of the first and second elements surrounding said outer portion includes a window through which only a segment of the dose-indicating scale on said portion is visible, the visible portion indicating the amount of liquid selected for injection.Type: GrantFiled: June 25, 1993Date of Patent: March 22, 1994Assignee: Eli Lilly and CompanyInventor: Dale C. Harris
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Patent number: 5228883Abstract: An improved drug delivery system comprising a gun style injection device used for holding and administering a disposable pre-filled drug cartridge, a holster device used for receiving an end of the gun style injection device and thereafter severing cannula from cartridge and disposing of spent cannulas and cartridges, and an improvement to the drug cartridge is disclosed. The gun style injection device comprises a barrel, a handle, a hinged and spring loaded squeeze lever, and a safety trigger. The holster device comprises a leg protection panel to which a housing is coupled for disposing of spent cartridges. The holster housing is adapted for receiving the barrel of the gun style injection device. The holster housing provides a means for severing the cannula from a used cartridge and disposing of both the cannula and cartridge in separate containers. The cartridge design itself is improved in order to increase the performance of the gun style injection device and the holster cannula severing mechanism.Type: GrantFiled: May 2, 1991Date of Patent: July 20, 1993Assignee: Eli Lilly and CompanyInventors: David C. Blakely, Dale C. Harris
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Patent number: 5226895Abstract: The present invention relates to a hypodermic syringe having the same general appearance as a pen which is specifically adapted to provide for multiple measured injections of materials such as insulin or human growth hormone.Type: GrantFiled: October 13, 1992Date of Patent: July 13, 1993Assignee: Eli Lilly and CompanyInventor: Dale C. Harris
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Patent number: 5226896Abstract: Two embodiments of a multi-dose syringe both include structure for indicating the selected amount of liquid to be injected. A first element and a second element coupled respectively to the syringe housing and the plunger rod are adapted for calibrated movement with respect to each other, one of the first and second elements includes an outer portion having dose-indicating scale thereon, and another of the first and second elements surrounding said outer portion includes a window through which only a segment of the dose-indicating scale on said portion is visible, the visible portion indicating the amount of liquid selected for injection.Type: GrantFiled: April 4, 1990Date of Patent: July 13, 1993Assignee: Eli Lilly and CompanyInventor: Dale C. Harris
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Patent number: 4981468Abstract: An improved device for containing and administering orally active therapeutic agents is described. A unit dose of a therapeutic agent in free-flowing form is retained and positioned for oral administration in a tube adapted to deliver the dose with a flow of liquid drawn through the tube by normal sipping action of a patient. The combination of small particle size and high flow rates into the alimentary canal allow dosage administration with minimal sensed contact with the oral cavity. The invention is particularly advantageous for the administration of orally active therapeutic agents to pediatric and geriatric patients.Type: GrantFiled: January 12, 1990Date of Patent: January 1, 1991Assignee: Eli Lilly and CompanyInventors: Robert L. Benefiel, John W. Clarke, Dale C. Harris, Robert J. Morff, Peter L. Oren
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Patent number: 4968303Abstract: A syringe holder for administering the contents of prefilled cartridge-cannula units comprises generally a cartridge holding barrel rotatably connected to a push rod guiding sleeve, and a push rod slidably mounted in the sleeve.Type: GrantFiled: September 27, 1988Date of Patent: November 6, 1990Assignee: Eli Lilly and CompanyInventors: John W. Clarke, Dale C. Harris
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Patent number: 4649042Abstract: An improved device for delivery of a medicament to the digestive tract of a ruminant animal comprises a polymeric medicated core retained in a dense tube by a relatively thick layer of an elastic sealant.Type: GrantFiled: April 3, 1985Date of Patent: March 10, 1987Assignee: Eli Lilly and CompanyInventors: Robert C. Davis, John W. Gibson, Daniel S. Skinner, Jr., Timothy E. Dearth, Dale C. Harris
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Patent number: 4573967Abstract: An apparatus for connecting a vial into the delivery tube of an intravenous administration set, the set including a container of fluid connected to one end of a delivery tube with the other end of the delivery tube adapted for insertion into the patient. The apparatus includes a penetrating spike penetrating an end of the vial which provides two pathways into the interior of the vial with two sections of the delivery tube connected to the two pathways of the penetrating spike. The apparatus also includes a frame for maintaining the two sections of the delivery tube adjacent to each other and clamp for releasably closing the adjacent sections of the delivery tube to temporarily prevent flow of fluid through the penetrating spike.Type: GrantFiled: December 6, 1983Date of Patent: March 4, 1986Assignee: Eli Lilly and CompanyInventors: William W. Hargrove, Dale C. Harris, Michael J. Akers, Charles R. Sperry
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Patent number: 4534758Abstract: Valved adaptors are disclosed permitting the introduction of a drug-containing vial in the delivery tube of an I.V. administration set. The adaptors have a three position operation characterized by a bypass mode, a dilution mode, and a delivery mode, the adaptors being manually changed from mode to mode. The disclosed adaptors include gravity operated valves, reciprocating spool valves, and rotating spool valves, each including a spike to penetrate the stopper of a vial and a vent to permit air to escape the vial as liquid is introduced to dilute the vial contents.Type: GrantFiled: July 15, 1983Date of Patent: August 13, 1985Assignee: Eli Lilly & CompanyInventors: Michael J. Akers, William W. Hargrove, Dale C. Harris, Charles R. Sperry
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Patent number: 4465471Abstract: The system of this invention provides a method and apparatus for the sterile intravenous administration of dry medicine. Such a system can include standard IV set components such as a source of liquid, means to inject liquid into a human vein, means forming a passageway between the source of liquid and said injection means, a valve to control the flow of liquid through the passageway, and a cartridge-like dry medicine package adapted for use with the system. Such a package can include conduit means adapted to perforate and communicate with the passageway, means forming a cell for dry, particulate medicine with portions forming a liquid-pervious barrier to the dry medicine and an air vent with an air-pervious, liquid barrier.Type: GrantFiled: July 26, 1982Date of Patent: August 14, 1984Assignee: Eli Lilly and CompanyInventors: Dale C. Harris, William W. Hargrove
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Patent number: 4415085Abstract: A system for the packaging, shipment, storage, and reconstitution of dry pharmaceuticals includes a flexible bag manufactured from two layers of plastic laminated film and a rigid port-forming member. In the system, the package is used for shipment and storage of dry pharmaceuticals and for their reconstitution in a liquid solution and their intravenous administration. A plurality of such packages may be handled as an assembly by flexible plastic strips both during processing and packaging and during the reconstitution of the dry medicine as a liquid solution. The flexible plastic strips are formed with a plurality of cavities. Each cavity of the strip has a plurality of sites located in its central portion and adapted to engage and retain the port-forming member and to protect its opening from contamination. A plurality of such package assemblies can be enclosed within an outer protective bag to provide protection against moisture and the effects of the environment during shipment and storage.Type: GrantFiled: December 21, 1981Date of Patent: November 15, 1983Assignee: Eli Lilly and CompanyInventors: John W. Clarke, Dale C. Harris
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Patent number: D262746Type: GrantFiled: October 29, 1979Date of Patent: January 19, 1982Assignee: Eli Lilly and CompanyInventor: Dale C. Harris