Abstract: A personalized and privatized method for the composition, distribution and ongoing data management of patient and practitioner surveys or diaries and other key information related to drug and medical clinical trials. The method is composed of a host data management system to manage and distribute standard or custom survey question sets and other information (such as schedules, instructions, and prescribed protocols) and two-way pagers “clients” utilizing custom resident software. The software residing on the two-way pager enables the pagers to receive, format and then transmit responses to survey and diary question sets and other interactions back to the host data management system via a page(s). The two-way pager provides a convenient and completely independent, mobile assessment capability that is able to immediately record and transmit results and interactions back to a data management system for storage, analysis, and auditing.