Abstract: An implantable electrical medical device includes (i) electronics configured to generate or receive an electrical signal and containing a plurality of channels through which the electrical signal may be transmitted; (ii) a first lead receptacle having a defined number of internal contacts, wherein each of the internal contacts are independently operably coupled to a discrete channel of the electronics; and (iii) a second lead receptacle having the same number of internal contacts as the first lead receptacle, and wherein each of the internal contacts of the second receptacle are independently operably coupled to a discrete channel of the electronics. Each channel of the electronics to which a contact of the first receptacle is operably coupled is also operably coupled to a channel of the second receptacle. The first and second lead receptacles are configured to receive leads having contacts with different spacing.

Abstract: Implantable medical devices include elongated conductor bodies and related features including an attachment to the medical device at one end and a connector that receives a medical lead at the other end. The connector may have various features such as a modular design whereby the connector is constructed from a series of stacked contact modules. Other features of the connector include electrical contacts that are relatively thin conductors or the order of 0.040 inches or less and that may include radial protrusions to establish contact with the electrical connectors of the lead. Furthermore, electrical contacts may be mounted within the connector in a floating manner so that radial movement of the electrical contact may occur during lead insertion. Additional features include a feedthrough where conductors exposed beyond a housing of the implantable medical device make direct electrical connection to conductors present within the elongated body.

Abstract: An implantable electrical medical device includes (i) electronics configured to generate or receive an electrical signal and containing a plurality of channels through which the electrical signal may be transmitted; (ii) a first lead receptacle having a first defined number of internal contacts, wherein each of the internal contacts are independently operably coupled to a discrete channel of the electronics; and (iii) a second lead receptacle having a second defined number of internal contacts, wherein the second defined number is less than the first defined number, and wherein each of the internal contacts of the second receptacle are independently operably coupled to a discrete channel of the electronics. At least one of the internal contacts of the first lead receptacle and at least one of the internal contacts of the second lead receptacle are operably coupled to the same channel of the electronics.

Abstract: Various embodiments of this disclosure concern assembly of a lead having one or two modular lead ends. A modular lead end can be made by aligning a plurality of wires exposed on an end of a main lead body with a plurality of conductors exposed on an end of a lead end. The lead end may comprise a spine, the plurality of conductors circumferentially arrayed about the spine, and an outer surface comprising a plurality of exposed electrical elements and polymer material, the plurality of electrical elements arrayed on the spine and electrically connected with the plurality of conductors. The assembly can further include making electrical connections between the plurality of electrical wires and the plurality of conductors and insulating the plurality of wires and the plurality of conductors.

Abstract: Prefilled reservoir apparatuses for use in ambulatory infusion devices include a rigid top and a flexible bag that forms at least a portion of a reservoir containing a liquid medicament composition. The reservoir apparatuses include a septum assembly that includes a fluid flow path in communication with the reservoir and a self-sealing septum disposed in or over the fluid flow path. The septum is positioned and configured to be pierced by a cannula of a base of an infusion device when the reservoir apparatus is received by the base.

Abstract: Various embodiments of this disclosure concern assembly of a lead having one or two modular lead ends. A modular lead end can be made by aligning a plurality of wires exposed on an end of a main lead body with a plurality of conductors exposed on an end of a lead end. The lead end may comprise a spine, the plurality of conductors circumferentially arrayed about the spine, and an outer surface comprising a plurality of exposed electrical elements and polymer material, the plurality of electrical elements arrayed on the spine and electrically connected with the plurality of conductors. The assembly can further include making electrical connections between the plurality of electrical wires and the plurality of conductors and insulating the plurality of wires and the plurality of conductors.

Abstract: Implantable medical devices include elongated conductor bodies and related features including an attachment to the medical device at one end and a connector that receives a medical lead at the other end. The connector may have various features such as a modular design whereby the connector is constructed from a series of stacked contact modules. Other features of the connector include electrical contacts that are relatively thin conductors or the order of 0.040 inches or less and that may include radial protrusions to establish contact with the electrical connectors of the lead. Furthermore, electrical contacts may be mounted within the connector in a floating manner so that radial movement of the electrical contact may occur during lead insertion. Additional features include a feedthrough where conductors exposed beyond a housing of the implantable medical device make direct electrical connection to conductors present within the elongated body.

Abstract: Image data can be obtained with an imaging device. A location of the imaging device relative to a subject can be determined. A location of an instrument can be tracked relative to the subject using a tracking system. Also, the tracked location of the instrument can be illustrated relative to the image data.

Abstract: Implantable medical devices include elongated conductor bodies and related features including an attachment to the medical device at one end and a connector that receives a medical lead at the other end. The connector may have various features such as a modular design whereby the connector is constructed from a series of stacked contact modules. Other features of the connector include electrical contacts that are relatively thin conductors or the order of 0.040 inches or less and that may include radial protrusions to establish contact with the electrical connectors of the lead. Furthermore, electrical contacts may be mounted within the connector in a floating manner so that radial movement of the electrical contact may occur during lead insertion. Additional features include a feedthrough where conductors exposed beyond a housing of the implantable medical device make direct electrical connection to conductors present within the elongated body.

Abstract: Implantable medical devices include headers having various features such as a modular design whereby the header is constructed from a series of stacked contact modules. Additional features include a feedthrough where pins exiting a housing of the implantable medical device extend into the header to make direct electrical connection to electrical contacts present within the header where those electrical contacts directly engage electrical connectors of leads inserted into the header. Other features include electrical contacts that are relatively thin conductors on the order of 0.040 inches or less and may include radial protrusions where the radial protrusions establish contact with the electrical connectors of the lead. Furthermore, electrical contacts may be mounted within the header in a floating manner so that radial movement of the electrical contact may occur during lead insertion.

Abstract: Implantable medical devices include elongated conductor bodies and related features including an attachment to the medical device at one end and a connector that receives a medical lead at the other end. The connector may have various features such as a modular design whereby the connector is constructed from a series of stacked contact modules. Other features of the connector include electrical contacts that are relatively thin conductors or the order of 0.040 inches or less and that may include radial protrusions to establish contact with the electrical connectors of the lead. Furthermore, electrical contacts may be mounted within the connector in a floating manner so that radial movement of the electrical contact may occur during lead insertion. Additional features include a feedthrough where conductors exposed beyond a housing of the implantable medical device make direct electrical connection to conductors present within the elongated body.

Abstract: An ambulatory infusion device includes a common module having a pump mechanism and a fluid flow path in communication with the pump mechanism. The device also includes a custom module operably coupleable to the common module. The custom module includes a reservoir for housing a liquid composition comprising a medicament and control electronics. The reservoir is configured to fluidly couple with the fluid flow path, and the control electronics are configured to electrically couple to the pump mechanism when the common module and the custom module are operably coupled. When the common module and the custom module are operably coupled, the pump mechanism is configured to drive the liquid composition from the reservoir to a patient via the fluid flow path, and the control electronics are configured to control the rate at which the pump mechanism drives the liquid composition.

Abstract: Prefilled reservoir apparatuses for use in ambulatory infusion devices include a rigid top and a flexible bag that forms at least a portion of a reservoir containing a liquid medicament composition. The reservoir apparatuses include a septum assembly that includes a fluid flow path in communication with the reservoir and a self-sealing septum disposed in or over the fluid flow path. The septum is positioned and configured to be pierced by a cannula of a base of an infusion device when the reservoir apparatus is received by the base.

Abstract: Titration schemes are carried out by medical infusion devices, such as ambulatory or implantable infusion devices. The titration schemes carried out by infusion systems and devices may take into account patient side effects in controlling the rate at which a medicament is delivered from the devices of systems.

Abstract: Implantable medical devices include elongated conductor bodies and related features including an attachment to the medical device at one end and a connector that receives a medical lead at the other end. The connector may have various features such as a modular design whereby the connector is constructed from a series of stacked contact modules. Other features of the connector include electrical contacts that are relatively thin conductors or the order of 0.040 inches or less and that may include radial protrusions to establish contact with the electrical connectors of the lead. Furthermore, electrical contacts may be mounted within the connector in a floating manner so that radial movement of the electrical contact may occur during lead insertion. Additional features include a feedthrough where conductors exposed beyond a housing of the implantable medical device make direct electrical connection to conductors present within the elongated body.

Abstract: A hub (200) includes a first lead receptacle having a plurality of contacts (280) for electrically coupling a lead to an implantable electrical device. The hub further contains a second lead receptacle having a plurality of contacts for electrically coupling a lead to the implantable electrical device. At least one of the plurality of contacts of the first receptacle is a contact of the second receptacle. Such a configuration may allow for the overall size of the hub to be reduced relative to a hub where each discrete contact of the hub corresponds to a discrete contact or electrical channel of the implantable electrical device.

Abstract: A medical lead includes a plurality of electrodes on an annular distal end portion of the lead. The electrodes may be arranged along a circle concentric with the center of a void defined by the annular portion. The annular medical lead design is well suited for application of electrical signal therapy to the suborbital nerve at its point of exit from the inferior orbital foramen in the skull.

Abstract: Multicomponent infusion device assemblies include locking and unlocking mechanisms that allow for locking and unlocking of components via actions capable of being carried out by at least some patients suffering from movement disorders. Tools or disengagement components may be used to unlock or disengage the components.

Abstract: In some examples, the disclosure relates to a medical device comprising a lead including an electrically conductive lead wire; and an electrode electrically coupled to the lead wire, the electrode including a substrate and a coating on an outer surface of the substrate, wherein the lead wire is formed of a composition comprising titanium or titanium alloys, wherein the substrate is formed of a composition comprising one or more of titanium, tantalum, niobium, and alloys thereof, wherein the coating comprises at least one of Pt, TiN, IrOx, and poly(dioctyl-bithiophene) (PDOT). In some examples, the lead wire may be coupled to the lead wire via a weld, such as, e.g., a laser weld.

Abstract: Various embodiments of this disclosure concern assembly of a lead having one or two modular lead ends. A modular lead end can be made by aligning a plurality of wires exposed on an end of a main lead body with a plurality of conductors exposed on an end of a lead end. The lead end may comprise a spine, the plurality of conductors circumferentially arrayed about the spine, and an outer surface comprising a plurality of exposed electrical elements and polymer material, the plurality of electrical elements arrayed on the spine and electrically connected with the plurality of conductors. The assembly can further include making electrical connections between the plurality of electrical wires and the plurality of conductors and insulating the plurality of wires and the plurality of conductors.