Patents by Inventor Dale G. Brown
Dale G. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220175703Abstract: In one aspect, this invention relates to a method for treating pain and subsequent resulting conditions. In yet another aspect, this invention relates to formulating agents to rapidly reverse painful conditions.Type: ApplicationFiled: February 21, 2022Publication date: June 9, 2022Inventors: Dale G. Brown, Ira D. Hill
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Publication number: 20200085864Abstract: Stannous fluoride polyol solid solutions combine three complimentary, biochemical mechanisms attributed to Sn++, F? and Polyol, respectively to reduce growth and metabolism of Streptococcus mutans while effecting superior Bioactivity Quotients. The stannous fluoride polyol solid solution particulate compositions of the present invention comprise: (a) stannous fluoride at between about 0.01 and about 0.8% by weight; (b) a polyol at between about 0.1 and about 30% by weight; (c) an astringency neutralizer at between about 0.01 and about 0.4% by weight, where the ratio of astringency neutralizer to stannous fluoride is from between about 0.01 and about 0.2; (d) a mucoadhesive at between about 1.Type: ApplicationFiled: May 10, 2019Publication date: March 19, 2020Inventors: Dale G. Brown, Ira D. Hill
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Publication number: 20190343907Abstract: In one aspect, this invention relates to a composition of matter useful for treating homeostatic malfunction and subsequent resulting conditions. In another aspect, this invention relates to the disclosure of unexpected synergies created by certain mixtures that increase the nature and function of those mixtures over any of the ingredients alone. In another aspect, this invention relates to a method for treating homeostatic instability conditions. In yet another aspect, this invention relates to formulating a synergistic agent to return mammalian systems to normal set point conditions—i.e., homeostasis—across a surprising number of different pain, inflammation and other expressions of non-homeostasis.Type: ApplicationFiled: May 10, 2019Publication date: November 14, 2019Inventors: Dale G. Brown, Ira D. Hill
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Patent number: 9877929Abstract: A topical vitamin D and UBIQUINOL supplement composition useful in treating oral inflammation and reducing oxidative stress comprising: a supplement mixture of vitamin D and UBIQUINOL in an aqueous-free emulsion containing: spilanthes extract, stabilizing compositions for UBIQUINOL and trans-oral mucosal absorption facilitators for the supplement mixture; where the emulsion forms a mucoadhesive gel in the presence of saliva, that effects passive diffusion through the oral mucosa of the supplement mixture and spilanthes extract regulating: in vivo availability and immune response of the supplement mixture, and maintaining adequate levels of circulating vitamin D and of adjunctively administered UBIQUINOL, while minimizing the risk of hypercalcemia.Type: GrantFiled: October 12, 2012Date of Patent: January 30, 2018Assignee: Premier Dental Products CompanyInventors: William A. McHale, Dale G. Brown
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Patent number: 9877930Abstract: Topical, UBIQUINOL, adjunctive, supplement compositions, containing amorphous calcium phosphate fluoride (ACPF), useful in: reducing oxidative stress, relieving oral discomfort and dry mouth, and remineralizing hydroxyapatite; comprising: UBIQUINOL in an aqueous-free emulsion that also contains: a stabilizing composition for UBIQUINOL, spilanthes extract, a trans-oral mucosal, absorption facilitator and ACPF; wherein: the emulsion forms a mucoadhesive gel in the presence of saliva that undergoes gradual saliva dissolution effecting passive diffusion of the UBIQUINOL supplement and the spilanthes extract into the oral mucosa, and remineralizing of tooth surfaces with ACPF; resulting in: adjunctively increasing UBIQUINOL levels, reducing oxidative stress, regulating immune response, relieving oral discomfort and dry mouth, and remineralizing tooth surfaces.Type: GrantFiled: October 12, 2012Date of Patent: January 30, 2018Assignee: Premier Dental Products CompanyInventors: William A. McHale, Dale G. Brown
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Patent number: 9724542Abstract: Improved remineralizing and desensitizing compositions containing remineralizing ingredients in aqueous-free emulsions that, in the presence of saliva, form mucoadhesive gels substantive to tooth surfaces; wherein the gels are dissolved by saliva gradually releasing remineralizing ingredients onto tooth surfaces, treatments with these compositions and methods of manufacture.Type: GrantFiled: October 12, 2012Date of Patent: August 8, 2017Assignee: Premier Dental Products CompanyInventors: William A. McHale, Dale G. Brown
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Patent number: 9616004Abstract: Substantially aqueous-free, enamel protectant and enamel repair toothpastes containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpastes indicate substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.Type: GrantFiled: April 11, 2014Date of Patent: April 11, 2017Assignee: Premier Dental Products CompanyInventors: William A. Mchale, Dale G. Brown
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Patent number: 9604078Abstract: A method of treatment for enamel with substantially aqueous-free, enamel protectant and repair brushing gels containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and said brushing gels have substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.Type: GrantFiled: April 11, 2014Date of Patent: March 28, 2017Assignee: Premier Dental Products CompanyInventors: William A. McHale, Dale G. Brown
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Patent number: 9586064Abstract: Substantially aqueous-free, enamel protectant and repair brushing gels containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and said brushing gels have substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.Type: GrantFiled: April 11, 2014Date of Patent: March 7, 2017Assignee: Premier Dental Products CompanyInventors: William A. McHale, Dale G. Brown
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Patent number: 9585818Abstract: Substantially aqueous-free, enamel protectant and enamel repair toothpaste treatments containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpaste treatments indicate substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.Type: GrantFiled: April 11, 2014Date of Patent: March 7, 2017Assignee: Premier Dental Products CompanyInventors: William A. Mchale, Dale G. Brown
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Patent number: 9149528Abstract: Topical, vitamin D, oral supplement compositions useful in treating oral inflammation comprising vitamin D in an aqueous-free emulsion containing a trans-oral mucosal absorption facilitator, where said emulsion forms a mucoadhesive coating in the presence of saliva; wherein saliva dissolution of the mucoadhesive gel releases vitamin D and the trans-oral mucosal, absorption facilitator; effecting: vitamin D passive diffusion; regulating in vivo availability and immune response of vitamin D; and maintaining adequate levels of circulating vitamin D while minimizing the risk of hypercalcemia.Type: GrantFiled: October 12, 2012Date of Patent: October 6, 2015Assignee: Premier Dental Products CompanyInventors: William A. McHale, Dale G. Brown
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Publication number: 20140301957Abstract: Substantially aqueous-free, enamel protectant and repair brushing gels containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and said brushing gels have substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.Type: ApplicationFiled: April 11, 2014Publication date: October 9, 2014Applicant: Premier Dental Products CompanyInventors: William A. MCHALE, Dale G. BROWN
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Publication number: 20140301956Abstract: A method of treatment for enamel with substantially aqueous-free, enamel protectant and repair brushing gels containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and said brushing gels have substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.Type: ApplicationFiled: April 11, 2014Publication date: October 9, 2014Applicant: Premier Dental Products CompanyInventors: William A. MCHALE, Dale G. BROWN
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Publication number: 20140294741Abstract: Substantially aqueous-free, enamel protectant and enamel repair toothpaste treatments containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpaste treatments indicate substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.Type: ApplicationFiled: April 11, 2014Publication date: October 2, 2014Applicant: Premier Dental Products CompanyInventors: William A. MCHALE, Dale G. BROWN
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Publication number: 20140219932Abstract: Substantially aqueous-free, enamel protectant and enamel repair toothpastes containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpastes indicate substantially improved, enamel protectant factor (EPF) and enamel repair factor (ERF) values compared to fluoride brushing treatments with comparable or higher fluoride levels.Type: ApplicationFiled: April 11, 2014Publication date: August 7, 2014Applicant: Premier Dental Products CompanyInventors: William A. Mchale, Dale G. Brown
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Publication number: 20140105937Abstract: Topical, UBIQUINOL, adjunctive, supplement compositions, containing amorphous calcium phosphate fluoride (ACPF), useful in: reducing oxidative stress, relieving oral discomfort and dry mouth, and remineralizing hydroxyapatite; comprising: UBIQUINOL in an aqueous-free emulsion that also contains: a stabilizing composition for UBIQUINOL, spilanthes extract, a trans-oral mucosal, absorption facilitator and ACPF; wherein: the emulsion forms a mucoadhesive gel in the presence of saliva that undergoes gradual saliva dissolution effecting passive diffusion of the UBIQUINOL supplement and the spilanthes extract into the oral mucosa, and remineralizing of tooth surfaces with ACPF; resulting in: adjunctively increasing UBIQUINOL levels, reducing oxidative stress, regulating immune response, relieving oral discomfort and dry mouth, and remineralizing tooth surfaces.Type: ApplicationFiled: October 12, 2012Publication date: April 17, 2014Applicant: Premier Dental Products CompanyInventors: William A. MCHALE, Dale G. Brown
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Publication number: 20140105941Abstract: Improved remineralizing and desensitizing compositions containing remineralizing ingredients in aqueous-free emulsions that, in the presence of saliva, form mucoadhesive gels substantive to tooth surfaces; wherein the gels are dissolved by saliva gradually releasing remineralizing ingredients onto tooth surfaces, treatments with these compositions and methods of manufacture.Type: ApplicationFiled: October 12, 2012Publication date: April 17, 2014Applicant: WhiteHill Oral Technologies, Inc.Inventors: William A. MCHALE, Dale G. BROWN
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Publication number: 20140107223Abstract: Topical, UBIQUINOL supplement compositions useful for treating skin by: reducing oxidative stress, adjunctively restoring “local” UBIQUINOL levels, revitalizing aged and/or U.V. damaged skin and regulating immune responses, including responses to inflammatory challenges; comprising: stabilized UBIQUINOL supplement, an emulsion of polydimethylsiloxane in a nonionic surfactant and skin penetrants.Type: ApplicationFiled: October 12, 2012Publication date: April 17, 2014Applicant: WhiteHill Oral Technologies, Inc.Inventor: Dale G. BROWN
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Publication number: 20090188520Abstract: Dental devices coated with substantially aqueous-free, saliva soluble, base coatings and ablative abrasives that break down during flossing; which combination creates the perception during flossing that said devices are working.Type: ApplicationFiled: January 30, 2008Publication date: July 30, 2009Applicant: WhiteHill Oral Technologies, Inc.Inventor: Dale G. Brown
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Patent number: D603047Type: GrantFiled: September 19, 2006Date of Patent: October 27, 2009Assignee: Optimedica CorporationInventors: David Haydn Mordaunt, Dale G. Brown