Abstract: A water control fixture configured to be fluidly coupled to a cold water supply line and a hot water supply line of a water circulating system includes a housing having a cold water inlet, a hot water inlet, and an outlet. The fixture also includes at least one operating valve disposed in the housing for controlling the flow of water from the cold water inlet and from the hot water inlet to the outlet, and a thermostatically controlled bypass valve disposed in the housing. The bypass valve is configured to bypass water from the hot water inlet to the cold water inlet based on a temperature of the water at the hot water inlet.

Abstract: A water control fixture having an operating valve and a thermostatically controlled bypass valve disposed in the fixture for bypassing water away from the fixture until the water temperature reaches a desired level. When pressurized water from the hot water heater reaches the desired temperature level at the fixture, the bypass valve closes and hot water is made available to the fixture. The bypass valve has a thermal actuator element that is thermally responsive to the temperature of the water. The fixture can have a housing with an interior chamber for operatively receiving the bypass valve. Various passages or channels can be provided to facilitate communication between the bypass valve and the water supply lines. Alternatively, the bypass valve can be positioned in the operating valve, including the moveable ball and the replaceable cylindrical valving cartridge types. A system using the in-fixture bypass valve is also provided.

Abstract: A water circulating system including a water control fixture having an operating valve and a thermostatically controlled bypass valve disposed in the fixture for bypassing water away from the fixture until the water temperature reaches a desired level. When pressurized water from the hot water heater reaches the desired temperature level at the fixture, the bypass valve closes and hot water is made available to the fixture. The bypass valve has a thermal actuator element that is thermally responsive to the temperature of the water. The fixture can have a housing with an interior chamber for operatively receiving the bypass valve. Various passages or channels can be provided to facilitate communication between the bypass valve and the water supply lines. Alternatively, the bypass valve can be positioned in the operating valve, which can include the moveable ball or replaceable cylindrical valving cartridge types of valves.

Abstract: Novel compounds of formula 1 or a pharmaceutically acceptable salt thereof inhibit cytochrome P450 monooxygenase.

Abstract: A water control valve configured for use with a bypass valve to automatically bypass cold or tepid water in a hot water supply line so as to maintain hot water at the fixture. The water control valve is useful for shower/tub facilities and for appliances such as washing machines and dishwashing machines. The water control valve for use with shower/tub facilities is adapted for the bypass valve to attach to or be adjacent to the water control valve by utilizing bypass ports, passageways and/or connectors. The water control valve for use with appliances is adapted to have a second outlet for connecting to a second water control valve or, for combination service valves, to have the bypass valve disposed in the tubular section between the hot and cold water components. The preferred bypass valve is a thermostatically controlled bypass valve of the type having a thermal actuating element.

Abstract: A water control fixture having an operating valve and a thermostatically controlled bypass valve disposed in the fixture for bypassing water away from the fixture until the water temperature reaches a desired level. When pressurized water from the hot water heater reaches the desired temperature level at the fixture, the bypass valve closes and hot water is made available to the fixture. The bypass valve has a thermal actuator element that is thermally responsive to the temperature of the water. The fixture can have a housing with an interior chamber for operatively receiving the bypass valve. Various passages or channels can be provided to facilitate communication between the bypass valve and the water supply lines. Alternatively, the bypass valve can be positioned in the operating valve, including the moveable ball and the replaceable cylindrical valving cartridge types. A system using the in-fixture bypass valve is also provided.

Abstract: A water control fixture having an operating valve and a thermostatically controlled bypass valve disposed in the fixture for bypassing water away from the fixture until the water temperature reaches a desired level. When pressurized water from the hot water heater reaches the desired temperature level at the fixture, the bypass valve closes and hot water is made available to the fixture. The bypass valve has a thermal actuator element that is thermally responsive to the temperature of the water. The fixture can have a housing with an interior chamber for operatively receiving the bypass valve. Various passages or channels can be provided to facilitate communication between the bypass valve and the water supply lines. Alternatively, the bypass valve can be positioned in the operating valve, including the moveable ball and the replaceable cylindrical valving cartridge types. A system using the in-fixture bypass valve is also provided.

Abstract: A water control fixture having an operating valve and a thermostatically controlled bypass valve disposed in the fixture for bypassing water away from the fixture until the water temperature reaches a desired level. When pressurized water from the hot water heater reaches the desired temperature level at the fixture, the bypass valve closes and hot water is made available to the fixture. The bypass valve has a thermal actuator element that is thermally responsive to the temperature of the water. The fixture can have a housing with an interior chamber for operatively receiving the bypass valve. Various passages or channels can be provided to facilitate communication between the bypass valve and the water supply lines. Alternatively, the bypass valve can be positioned in the operating valve, including the moveable ball and the replaceable cylindrical valving cartridge types. A system using the in-fixture bypass valve is also provided.

Abstract: A water control fixture having an operating valve and a thermostatically controlled bypass valve disposed in the fixture for bypassing water away from the fixture until the water temperature reaches a desired level. When pressurized water from the hot water heater reaches the desired temperature level at the fixture, the bypass valve closes and hot water is made available to the fixture. The bypass valve has a thermal actuator element that is thermally responsive to the temperature of the water. The fixture can have a housing with an interior chamber for operatively receiving the bypass valve. Various passages or channels can be provided to facilitate communication between the bypass valve and the water supply lines. Alternatively, the bypass valve can be positioned in the operating valve, including the moveable ball and the replaceable cylindrical valving cartridge types. A system using the in-fixture bypass valve is also provided.

Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

Abstract: The present invention provides an HCV polymerase inhibiting compound having the formula (I) and a composition comprising a therapeutically effective amount of said compound. The present invention also provides a method for inhibiting hepatitis C virus (HCV) polymerase, a method for inhibiting HCV viral replication, and a method for treating or preventing HCV infection. Processes for making said compounds, and synthetic intermediates employed in said processes, are also provided.

Abstract: Apparatuses and system for retrofitting an existing water control valve mounted in a water distribution system that allows the user to quickly and easily replace the functions of the existing water control valve with updated and additional features in a new retrofit valve without having to remove or replace the existing valve manifold. An adapter plug having an interface corresponding to the existing valve cartridge interface is inserted into the open valve cavity to hydraulically connect with the existing valve cartridge interface. Fluid passages transfer fluid through the adapter plug to one or more fluid connectors that transfer fluid between the adapter plug and a retrofit valve. The retrofit valve has a fluid chamber with a water control cartridge, having features such as pressure balancing, disposed therein. The retrofit valve can include a second fluid chamber with a bypass valve disposed therein to provide an instant hot water feature.

Abstract: The present invention concerns a club for impacting an object. The club may have a club head having a club face. At least one microprocessor in communication with a plurality of infrared sources is also provided. There are also a plurality of infrared sensors, and indicators configurable in a configuration indicating proper club face alignment and a configuration indicating club face misalignment. The infrared sources are periodically pulsed by a microprocessor between an activated and deactivated state. The sensors are configured on the club head to receive infrared from the infrared sources and to generate a signal in response to the infrared received. The device may be used outside, even in the presence of sunlight. By filtering direct current, the false readings caused by sunlight may be reduced. Pulsing the infrared sources, e.g., at 2-6 kilohertz, also helps reduce the detrimental effects sunlight has on the operation of the device.

Abstract: The present invention concerns a club for impacting an object. The club may have a club head having a club face. At least one microprocessor in communication with a plurality of infrared sources is also provided. There are also a plurality of infrared sensors, and indicators configurable in a configuration indicating proper club face alignment and a configuration indicating club face misalignment. The infrared sources are periodically pulsed by a microprocessor between an activated and deactivated state. The sensors are configured on the club head to receive infrared from the infrared sources and to generate a signal in response to the infrared received. The microprocessor is programmed to receive signals from the sensors when the infrared sources are activated. The microprocessor is programmed to activate the indicators in an aligned or misaligned configuration.

Abstract: A water control valve configured for use with a bypass valve to automatically bypass cold or tepid water in a hot water supply line so as to maintain hot water at the fixture. The water control valve is useful for shower/tub facilities and for appliances such as washing machines and dishwashing machines. The water control valve for use with shower/tub facilities is adapted for the bypass valve to attach to or be adjacent to the water control valve by utilizing bypass ports, passageways and/or connectors. The water control valve for use with appliances is adapted to have a second outlet for connecting to a second water control valve or, for combination service valves, to have the bypass valve disposed in the tubular section between the hot and cold water components. The preferred bypass valve is a thermostatically controlled bypass valve of the type having a thermal actuating element.

Abstract: The present invention concerns a club for impacting an object. The club may have a club head having a club face. At least one microprocessor in communication with a plurality of infrared sources is also provided. There are also a plurality of infrared sensors, and indicators configurable in a configuration indicating proper club face alignment and a configuration indicating club face misalignment. The infrared sources are periodically pulsed by a microprocessor between an activated and deactivated state. The sensors are configured on the club head to receive infrared from the infrared sources and to generate a signal in response to the infrared received. The microprocessor is programmed to receive signals from the sensors when the infrared sources are activated. The microprocessor is programmed to activate the indicators in an aligned or misaligned configuration.

Abstract: A thermostatically controlled bypass valve for bypassing water away from a hot water valve until the water temperature reaches a desired level at a fixture in use for home or industrial applications. The bypass valve has a valve body with a thermally sensitive actuator disposed between the hot water inlet and discharge ports and the cold water inlet and discharge ports that is thermally responsive to the temperature of the water. A bias spring pushes against the piston on the thermal actuator to close the actuator and open a passage between the cold and hot water sides when water needs to be bypassed. When the water from the hot water heater reaches the desired temperature level at the bypass valve, the bypass valve closes and hot water is made available to the hot water side of the fixture. Until then, the thermal actuator remains open and cold or tepid water is allowed to bypass the hot water side of the fixture.