Abstract: Methods of effectively repelling vertebrates, especially rodents, from consuming or utilizing materials otherwise susceptible to such consumption or utilization, using at least one non-toxic rodent repellent compound selected from the group comprising acetophenone, 2-aminobenzyl alcohol, 2-amino-4'5'-dimethoxyacetophenone, anthranilamide, anthranilic acid, isobutyl anthranilate, 4-ketobenztriazine, meta-aminoacetophenone, meta-hydroxyacetophenone, meta-methoxyacetophenone, 2-methoxybenzoic acid, methylanthranilate, ortho-aminoacetophenone, ortho-hydroxyacetophenone, ortho-methoxyacetophenone, para-aminoacetophenone, para-hydroxyacetophenone, para-methoxyacetophenone, and veratryl amine, are provided herein. Certain embodiments of the present invention relate to materials and methods for reducing crop damage, feedlot depredation, and livestock disease attributed to rodent infestation.