Patents by Inventor Dale S. Dhanoa

Dale S. Dhanoa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
    Publication number: 20030220380
    Abstract: The present invention relates to the use of aminothiazole derivatives of Formula I of as inhibitors of PAI-1, and to novel classes of aminothiazole derivatives, their synthesis and their use as inhibitors of PAI-1.
    Type: Application
    Filed: April 22, 2003
    Publication date: November 27, 2003
    Applicant: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Dale S. Dhanoa, Declan E. Ryan, Ingrid Deckman, Anthony Sapienza
  • Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
    Patent number: 6586453
    Abstract: The present invention relates to the use of aminothiazole derivatives of Formula I of as inhibitors of PAI-1, and to novel classes of aminothiazole derivatives, their synthesis and their use as inhibitors of PAI-1. It has been discovered that compounds of Formula I: or a solvate, hydrate or a pharmaceutically acceptable salt thereof, wherein Y, Ar1, Ar2, R1, R2, Z, m and n are described in the specification, inhibit plasminogen activator inhibitor-1 (PAI-1). These compounds can be used in the prophylaxis or for the treatment of thrombosis, angina pectoris, cerebral infarction, myocardial infarction, pulmonary infarction, intra-atrial thrombus in atrial fibrillation, deep venous thrombus, disseminated intravascular coagulation syndrome, diabetic complications, restenosis and stroke.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: July 1, 2003
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Dale S. Dhanoa, Declan E. Ryan, Ingrid Deckman, Anthony Sapienza
  • Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
    Publication number: 20010044545
    Abstract: The present invention relates to the use of aminothiazole derivatives of Formula I of as inhibitors of PAI-1, and to novel classes of aminothiazole derivatives, their synthesis and their use as inhibitors of PAI-1.
    Type: Application
    Filed: April 2, 2001
    Publication date: November 22, 2001
    Applicant: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Dale S. Dhanoa, Declan E. Ryan, Ingrid Deckman, Anthony Sapienza
  • Benzoperimidine-carboxylic acids and derivatives thereof
    Patent number: 5861398
    Abstract: Benzo(e)perimidine-4-carboxamide derivatives of general structural formula I ##STR1## (where R.sub.a, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are as defined in the specification) have activity for receptors of corticotropin releasing factor (CRF). The compounds are useful in treating stress-related diseases, cardiovascular, neurological and psychiatric disorders including anxiety, depression, eating disorders, anorexia nervosa, superanuclear palsy, irritable bowel syndrome, gastrointestinal diseases, immune suppression, inflammatory disorders, drug and alcohol withdrawal symptoms, drug addiction, Alzheimer's disease or fertility disorders.
    Type: Grant
    Filed: August 26, 1996
    Date of Patent: January 19, 1999
    Assignee: Alanex Corporation
    Inventors: Aleksandr K. Rabinovich, Dale S. Dhanoa, David R. Luthin, Richard A. Bychowski, Dilip R. Bhumralkar