Patents by Inventor Dale Swan

Dale Swan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120046384
    Abstract: Described herein is a degradable linking agent of formula Photo1-LG-Photo2, wherein Photo1 and Photo2 independently represent at least one photoreactive group and LG represents a linking group comprising one or more silicon atoms or one or more phosphorous atoms. The degradable linking agent includes a covalent linkage between at least one photoreactive group and the linking group, wherein the covalent linkage between at least one photoreactive group and the linking group is interrupted by at least one heteroatom. A method for coating a support surface with the degradable linking agent, coated support surfaces and medical devices are also described.
    Type: Application
    Filed: March 29, 2011
    Publication date: February 23, 2012
    Applicant: SurModics, Inc.
    Inventors: Aleksey Kurdyumov, Dale Swan
  • Publication number: 20080114451
    Abstract: A coating composition, in both its uncrosslinked and crosslinked forms, for use in increasing the static friction of a surface of a delivery system comprising a medical device having a surface in contact with the surface of a delivery component, the static friction of the surface being increased in an amount sufficient to substantially maintain the position of the medical device on the delivery component against forces asserted on the delivery system as it navigates through a vessel of the body. The delivery system may comprise a balloon catheter as the delivery component and a stent as the medical device. A composition includes a polyether monomer, such as an alkoxy poly(alkylene glycol), a carboxylic acid-containing monomer, such as (meth)acrylic acid, optionally a photoderivatized monomer, and a hydrophilic monomer such as (meth)acrylamide.
    Type: Application
    Filed: January 18, 2008
    Publication date: May 15, 2008
    Inventors: Sean Stucke, Kimberly Lindsoe, Ralph Chappa, Dale Swan
  • Publication number: 20080090959
    Abstract: Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes epoxide groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.
    Type: Application
    Filed: October 18, 2007
    Publication date: April 17, 2008
    Applicant: SurModics, Inc.
    Inventors: Dale Swan, Melvin Swanson
  • Publication number: 20070292596
    Abstract: A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate.
    Type: Application
    Filed: August 29, 2007
    Publication date: December 20, 2007
    Applicant: SURMODICS, INC.
    Inventors: Ralph Chappa, Sean Stucke, Richard Amos, Terrence Everson, Stephen Chudzik, Dale Swan, Peter Duquette
  • Publication number: 20070065484
    Abstract: In situ formed biodegradable occlusions including natural biodegradable polysaccharides are described. The matrix is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.
    Type: Application
    Filed: September 21, 2006
    Publication date: March 22, 2007
    Inventors: Stephen Chudzik, Joseph Chinn, Dale Swan, Michael Burkstrand, Peter Duquette
  • Publication number: 20070065482
    Abstract: Medical articles having a body member including natural biodegradable polysaccharides are described. The body member is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups. The body member can also include a bioactive agent which can be released to provide a therapeutic effect to a patient.
    Type: Application
    Filed: November 11, 2005
    Publication date: March 22, 2007
    Inventors: Stephen Chudzik, Dale Swan, Michael Burkstrand
  • Publication number: 20070065483
    Abstract: In vivo formed matrices including natural biodegradable polysaccharides are described. The matrix is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups. The matrix can also include a bioactive agent which can be released to provide a therapeutic effect to a patient.
    Type: Application
    Filed: November 11, 2005
    Publication date: March 22, 2007
    Inventors: Stephen Chudzik, Dale Swan, Michael Burkstrand
  • Publication number: 20070065481
    Abstract: Biodegradable coatings and articles that include natural biodegradable polysaccharides are described. The coatings and articles are formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.
    Type: Application
    Filed: November 11, 2005
    Publication date: March 22, 2007
    Inventors: Stephen Chudzik, Joseph Chinn, Dale Swan, Michael Burkstrand
  • Publication number: 20050281857
    Abstract: Polymeric coatings that include coupled biomolecules are formed on the surface of articles, such as medical devices. A coated layer that includes a synthetic polymer including a reactive group is formed on a surface and then a biomolecule is attached to the reactive group. The synthetic polymer can be an acrylate polymer or an amine-containing polymer having pendent photoreactive groups.
    Type: Application
    Filed: May 25, 2005
    Publication date: December 22, 2005
    Inventors: Toni Heyer, Dale Swan, Stephen Chudzik, Joseph Chinn, Ralph Chappa
  • Publication number: 20050255142
    Abstract: Biodegradable coatings that include natural biodegradable polysaccharides are described. The coating is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.
    Type: Application
    Filed: May 12, 2005
    Publication date: November 17, 2005
    Inventors: Stephen Chudzik, Joseph Chinn, Dale Swan, Michael Burkstrand
  • Publication number: 20050232812
    Abstract: Compounds useful as surface coating agents, including compounds of the formula: wherein X1 comprises a first photoreactive species; X2 comprises a second photoreactive species; Y comprises a nonpolymeric core molecule comprising an aromatic group; and Z comprises at least one charged group. The Y core can include an aromatic group such as a benzene radical, the charged groups Z can be independently selected from the organic acids that include sulfonic acid, carboxylic acid, and phosphoric acid, and the photoreactive species of X1 and X2 can independently be aryl ketones, such as those selected from the group acetophenone, benzophenone, anthraquinone, anthrone, and anthrone-like heterocycles, and their substituted derivatives.
    Type: Application
    Filed: June 20, 2005
    Publication date: October 20, 2005
    Inventor: Dale Swan
  • Publication number: 20050170427
    Abstract: Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.
    Type: Application
    Filed: April 6, 2005
    Publication date: August 4, 2005
    Applicant: SurModics, Inc.
    Inventors: Ralph Chappa, Sheau-Ping Hu, Dale Swan, Melvin Swanson, Patrick Guire
  • Publication number: 20050112086
    Abstract: The present invention provides method and materials for forming a polymeric matrix having improved biocompatible properties. A polymerization accelerator is provided that includes an N-vinyl group and a biocompatible functional group. The polymerization accelerator is particularly useful for the polymerization of macromers, which can be used to form biocompatible polymeric coatings on the surface of biological materials, such as cells and tissue.
    Type: Application
    Filed: November 26, 2003
    Publication date: May 26, 2005
    Inventors: Dale Swan, Stephen Chudzik, Ronald Ofstead
  • Publication number: 20050074478
    Abstract: The present invention relates to methods, reagents, and substrates that can be used for, for example, immobilizing biomolecules, such as nucleic acids and proteins. In an embodiment, the present invention relates to surfaces coated with a polymer according to the present invention. In an embodiment, the present invention relates to methods for thermochemically and/or photochemically attaching molecules to a surface at a high density.
    Type: Application
    Filed: October 1, 2003
    Publication date: April 7, 2005
    Applicant: SurModics, Inc.
    Inventors: Ronald Ofstead, Melvin Swanson, Dale Swan