Abstract: The present invention provides novel antibodies to human CXCR4 with high affinity to the target and the ability to act potently as antagonists. The antibodies disclosed herein bind to a diverse range of epitopes.

Abstract: The present invention provides novel antibodies to human ADORA2A.

Abstract: The present invention provides novel antibodies to human CXCR4 with high affinity to the target and the ability to act potently as antagonists. The antibodies disclosed herein bind to a diverse range of epitopes.

Abstract: Analytes and ligands for detecting animal byproduct in agricultural samples such as animal feed to minimize the transmission of prion pathogens into food products consumed by humans. The analyte is a component of rendered animal byproduct such as meat and bone meal (MBM). An antibody specific for the analyte is produced by immunizing an animal with MBM or an immunogenic component of MBM that is found in rendered animal product.

Abstract: Analytes and ligands for detecting animal byproduct in agricultural samples such as animal feed to minimize the transmission of prion pathogens into food products consumed by humans. The analyte is a component of rendered animal byproduct such as meat and bone meal (MBM). An antibody specific for the analyte is produced by immunizing an animal with MBM or an immunogenic component of MBM that is found in rendered animal product.

Abstract: A method, kit and reagents for the detection of (phosphinothricin-N-acetyltransferase) PAT proteins in a sample, particularly a genetically modified agricultural crop sample. The proteins to be detected are one or more PAT enzyme proteins from various species of Streptomyces, including S. hygroscopicus and S. viridochromogenes. In particular, the PAT proteins are detected in genetically modified plants containing a gene, such as the pat or bar gene, that renders the plant resistant to the herbicide glufosinate. The reagents are antigenic peptides having common epitope of the PAT proteins from two or more Streptomyces species and antibodies immunoreactive with these proteins, particularly those expressed by the bar and pat genes. The peptides are isolated or synthesized and administered to animals to produce anti-PAT monoclonal and polyclonal antibodies having high sensitivity for PAT proteins.

Abstract: Reagents, immunoassay methods, and kits for detecting the presence or amount of trichloroethylene or perchloroethylene in a sample. Reagents include antibodies, immunogens for preparing antibodies, and assay conjugates. The immunogens elicit high affinity antibodies to trichloroethylene. The antibodies have minimal crossreactivity to other halogenated and aromatic hydrocarbons. The assay conjugates provide for sufficient binding of the antibody to the conjugate with maximum inhibition of that binding by free trichloroethylene and perchloroethylene in the sample. The reagents are useful in immunoassays to detect trichloroethylene and perchloroethylene, especially in environmental samples. Kits contain antibodies specific for trichloroethylene and perchloroethylene and assay conjugates.