Patents by Inventor Dalia Reznitsky-Cohen

Dalia Reznitsky-Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPOPHILIC DIESTERS OF CHELATING AGENT FOR INHIBITION OF ENZYME ACTIVITY
    Publication number: 20110105607
    Abstract: The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N?,N?-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE The invention further relates to methods for preventing, treating or managing TACE-related diseases or disorders in mammals comprising administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of said lipophilic diesters of the chelating agent BAPTA.
    Type: Application
    Filed: August 12, 2010
    Publication date: May 5, 2011
    Applicant: D-PHARM Ltd.
    Inventors: Sarina STRIEM, Jonathan Eduard Friedman, Dalia Reznitsky-Cohen, Alexander Kozak
  • Lipophilic diesters of chelating agent for inhibition of enzyme activity
    Patent number: 7799831
    Abstract: The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N?,N?-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases and of calpain. The invention further relates to methods for preventing, treating or managing MMP-related and calpain-related diseases or disorders in mammals comprising administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of said lipophilic diesters of the chelating agent BAPTA.
    Type: Grant
    Filed: March 16, 2003
    Date of Patent: September 21, 2010
    Assignee: D-Pharm Ltd.
    Inventors: Sarina Striem, Jonathan Eduard Friedman, Dalia Reznitsky-Cohen, Alexander Kozak
  • Derivatives of branch-chain lipophilic molecular and uses thereof
    Patent number: 7687483
    Abstract: Novel phospho-derivatives of branched-chain lipophilic molecules useful for permeabilizing biological barriers and for inhibiting tumor growth are disclosed. Pharmaceutical compositions comprising phospho-derivatives of branched-chain lipophilic molecules and their uses are also disclosed.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: March 30, 2010
    Assignee: D-Pharm Ltd.
    Inventors: Alexander Kozak, Marina Vinnikova, Michael Polyak, Eliezer Beit-Yannai, Dalia Reznitsky-Cohen, Alexander Senderikhin
  • Derivatives of branched-chain lipophilic molecules and uses thereof
    Patent number: 7186703
    Abstract: The present invention discloses novel phospho-derivatives of branched-chain lipophilic molecules useful for permeabilizing biological barriers and for inhibiting tumor growth. The invention further discloses pharmaceutical compositions comprising said molecules and their uses.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: March 6, 2007
    Assignee: D-Pharm Ltd.
    Inventors: Alexander Kozak, Marina Vinnikova, Michael Polyak, Eliezer Beit-Yannai, Dalia Reznitsky-Cohen, Alexander Senderikhin
  • Lipophilic diesters of chelating agent for inhibition of enzyme activity
    Publication number: 20060167092
    Abstract: The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N?,N?-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases and of calpain. The invention further relates to methods for preventing, treating or managing MMP-related and calpain-related diseases or disorders in mammals comprising administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of said lipophilic diesters of the chelating agent BAPTA.
    Type: Application
    Filed: March 16, 2003
    Publication date: July 27, 2006
    Applicant: D-Pharm Ltd
    Inventors: Sarina Striem, Jonathan Friedman, Dalia Reznitsky-Cohen, Alexander Kozak
  • Derivatives of branched-chain lipophilic molecules and uses thereof
    Publication number: 20030186897
    Abstract: The present invention discloses novel phospho-derivatives of branched-chain lipophilic molecules useful for permeabilizing biological barriers and for inhibiting tumor growth. The invention further discloses pharmaceutical compositions comprising said molecules and their uses.
    Type: Application
    Filed: January 27, 2003
    Publication date: October 2, 2003
    Inventors: Alexander Kozak, Marina Vinnikova, Michael Polyak, Eliezer Beit-Yannai, Dalia Reznitsky-Cohen, Alexander Senderikhin