Patents by Inventor Dalit Tchorsh

Dalit Tchorsh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for hematopoietic precursor mobilization
    Patent number: 9610331
    Abstract: Methods of modulating mobilization of cells from the bone marrow are provided. In a specific embodiment there is provided a method of increasing mobilization of hematopoietic precursors from the bone marrow to the peripheral blood in a subject in need thereof, the method comprising: (a) administering to the subject an agent which downregulates an activity or expression of a coagulation factor or an effector thereof; and (b) harvesting the hematopoietic precursors from the peripheral blood.
    Type: Grant
    Filed: September 5, 2010
    Date of Patent: April 4, 2017
    Assignees: Yeda Research and Development Co. Ltd., Tel HaShomer Medical Research Infrastructure and Services Ltd.
    Inventors: Anna Aronovich, Dalit Tchorsh-Yutsis, Gideon Rechavi, Yair Reisner
  • THERAPEUTIC TRANSPLANTATION USING DEVELOPING, HUMAN OR PORCINE, RENAL OR HEPATIC, GRAFTS
    Publication number: 20150190546
    Abstract: A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage.
    Type: Application
    Filed: February 9, 2015
    Publication date: July 9, 2015
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Yair REISNER, Benjamin DEKEL, Smadar EVENTOV-FRIEDMAN, Helena KATCHMAN, Elias SHEZEN, Anna ARONOVICH, Dalit TCHORSH-YUTSIS
  • DISEASE TREATMENT VIA DEVELOPING NON-SYNGENEIC GRAFT TRANSPLANTATION
    Publication number: 20150174294
    Abstract: A method of providing a pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function to a mammalian subject is provided. The method comprises transplanting into the subject a developing mammalian pancreatic, lymphoid/hematopietic or pulmonary organ/tissue graft, respectively, thereby generating a functional pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue, respectively, for providing the pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function, respectively, to the subject.
    Type: Application
    Filed: March 9, 2015
    Publication date: June 25, 2015
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Yair REISNER, Benjamin DEKEL, Smadar EVENTOV-FRIEDMAN, Helena KATCHMAN, Elias SHEZEN, Anna ARONOVICH, Dalit TCHORSH-YUTSIS
  • Disease treatment via developing non-syngeneic graft transplantation
    Patent number: 8974779
    Abstract: A method of providing a pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function to a mammalian subject is provided. The method comprises transplanting into the subject a developing mammalian pancreatic, lymphoid/hematopietic or pulmonary organ/tissue graft, respectively, thereby generating a functional pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue, respectively, for providing the pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function, respectively, to the subject.
    Type: Grant
    Filed: October 2, 2005
    Date of Patent: March 10, 2015
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yair Reisner, Benjamin Dekel, Smadar Eventov-Friedman, Helena Katchman, Elias Shezen, Anna Aronovich, Dalit Tchorsh
  • Therapeutic transplantation using developing, human or porcine, renal or hepatic, grafts
    Patent number: 8951572
    Abstract: A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: February 10, 2015
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yair Reisner, Benjamin Dekel, Smadar Eventov-Friedman, Helena Katchman, Elias Shezen, Anna Aronovich, Dalit Tchorsh
  • Disease treatment via developing non-syngeneic graft transplantation
    Publication number: 20150010512
    Abstract: A method of providing a pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function to a mammalian subject is provided. The method comprises transplanting into the subject a developing mammalian pancreatic, lymphoid/hematopietic or pulmonary organ/tissue graft, respectively, thereby generating a functional pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue, respectively, for providing the pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function, respectively, to the subject.
    Type: Application
    Filed: October 2, 2005
    Publication date: January 8, 2015
    Applicant: Yeda Research And Development Co. Ltd.
    Inventors: Yair Reisner, Benjamin Dekel, Smadar Eventov-Friedman, Helena Katchman, Elias Shezen, Anna Aronovich, Dalit Tchorsh
  • IMMUNOSUPPRESSIVE DRUG COMBINATION FOR A STABLE AND LONG TERM ENGRAFTMENT
    Publication number: 20130183322
    Abstract: A method of treating a subject in need of a cell or tissue transplant is disclosed. The method comprising (a) transplanting a non-syngeneic cell or tissue transplant into the subject, wherein the transplant comprises bone marrow or lymphoid cells; and (b) administering to the subject a therapeutically effective amount of an immunosuppressive regimen comprising a Sphingosine 1-Phosphate Receptor Agonist, a B7 molecule inhibitor and a CD2/CD58 pathway inhibitor, thereby treating the subject.
    Type: Application
    Filed: September 8, 2011
    Publication date: July 18, 2013
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Yair Reisner, Esther Bachar-Lustig, Dalit Tchorsh-Yutsis
  • METHODS FOR HEMATOPOIETIC PRECURSOR MOBILIZATION
    Publication number: 20120189574
    Abstract: Methods of modulating mobilization of cells from the bone marrow are provided. In a specific embodiment there is provided a method of increasing mobilization of hematopoietic precursors from the bone marrow to the peripheral blood in a subject in need thereof, the method comprising: (a) administering to the subject an agent which downregulates an activity or expression of a coagulation factor or an effector thereof; and (b) harvesting the hematopoietic precursors from the peripheral blood.
    Type: Application
    Filed: September 5, 2010
    Publication date: July 26, 2012
    Applicants: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD., YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Anna Aronovich, Dalit Tchorsh-Yutsis, Gideon Rechavi, Yair Reisner
  • COAGULATION FACTOR MODULATION FOR CONTROLLING TRANSPLANT ORGAN SIZE
    Publication number: 20110236405
    Abstract: A method of modulating transplant organ size in a subject in need thereof is disclosed. The method comprising: (a) administering to the subject an agent capable of modulating an activity or expression of a coagulation factor or an effector thereof; and (b) transplanting the organ into the subject; thereby modulating the transplant organ size in the subject.
    Type: Application
    Filed: July 19, 2009
    Publication date: September 29, 2011
    Applicant: Tel HaShomer Medical Research Infrastructure and Services Ltd.
    Inventors: Yair Reisner, Anna Aronovich, Dalit Tchorsh-Yutsis, Gideon Rechavi
  • THERAPEUTIC TRANSPLANTATION USING DEVELOPING, HUMAN OR PORCINE, RENAL OR HEPATIC, GRAFTS
    Publication number: 20100221270
    Abstract: A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage.
    Type: Application
    Filed: May 11, 2010
    Publication date: September 2, 2010
    Applicant: Yeda Research And Development Co. Ltd.
    Inventors: Yair REISNER, Benjamin Dekel, Smadar Eventov-Friedman, Helena Katchman, Elias Shezen, Anna Aronovich, Dalit Tchorsh
  • Therapeutic transplantation using developing, human or porcine, renal or hepatic, grafts
    Patent number: 7780993
    Abstract: A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: August 24, 2010
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yair Reisner, Benjamin Dekel, Smadar Eventov-Friedman, Helena Katchman, Elias Shezen, Anna Aronovich, Dalit Tchorsh
  • Disease treatment via developing non-syngeneic graft transplantation
    Publication number: 20100021433
    Abstract: A method of providing a pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function to a mammalian subject is provided. The method comprises transplanting into the subject a developing mammalian pancreatic, lymphoid/hematopietic or pulmonary organ/tissue graft, respectively, thereby generating a functional pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue, respectively, for providing the pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function, respectively, to the subject.
    Type: Application
    Filed: October 2, 2005
    Publication date: January 28, 2010
    Applicant: Yeda Research And Development Co. Ltd.
    Inventors: Yair Reisner, Benjamin Dekel, Smadar Eventov-Friedman, Helena Katchman, Elias Shezen, Anna Aronovich, Dalit Tchorsh
  • Therapeutic Transplantation Using Developing, Human or Porcine, Renal or Hepatic, Grafts
    Publication number: 20090324607
    Abstract: A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage.
    Type: Application
    Filed: January 19, 2006
    Publication date: December 31, 2009
    Applicant: Yeda Research And Development Co. Ltd.
    Inventors: Yair Reisner, Benjamin Dekel, Smadar Eventov-Friedman, Helena Katchman, Elias Shezen, Anna Aronovich, Dalit Tchorsh
  • Therapeutic transplantation using developing, human or porcine, renal or hepatic, grafts
    Publication number: 20050226854
    Abstract: A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage.
    Type: Application
    Filed: January 19, 2005
    Publication date: October 13, 2005
    Inventors: Yair Reisner, Benjamin Dekel, Smadar Eventov-Friedman, Helena Katchman, Elias Shezen, Anna Aronovich, Dalit Tchorsh