Abstract: Systems and methods for use in identifying a trial in a target field are provided. One example computer-implemented method includes accessing, for a target field, planting data for the target field from a data structure and identifying one or multiple segment(s) of the target field having a feature distinct from a remainder of the field. The method also includes applying a first geometric threshold to the identified segment(s) and, in response to the identified segment(s) satisfying the first geometric threshold: validating a strip including the segment(s), based on a length and width of the strip, and building a trial based on the strip, wherein the trial includes the strip and at least one duplicate strip disposed along a long side of the strip, where the trial is identified as a location of the trial in the target field.

Abstract: Virtual application and desktop delivery may be optimized by supplying application metadata and user intent to the device between a client and a server hosting resources for the delivery. The data packets used to deliver the virtual application or desktop may be also tagged with references to the application. By supplying the metadata and tagging packets with the metadata, an intermediary network device may provide streams of data packets at the target QoS. In addition, the device may apply network resource allocation rules (e.g., firewalls and QoS configuration) for redirected content retrieved by the client out of band relative to a virtual channel such as the Internet. The network resource allocation rules may differ for different types of resources accessed. The device may also control a delivery agent on the server to modify communication sessions established through the virtual channels based on network conditions.

Abstract: Virtual application and desktop delivery may be optimized by supplying application metadata and user intent to the device between a client and a server hosting resources for the delivery. The data packets used to deliver the virtual application or desktop may be also tagged with references to the application. By supplying the metadata and tagging packets with the metadata, an intermediary network device may provide streams of data packets at the target QoS. In addition, the device may apply network resource allocation rules (e.g., firewalls and QoS configuration) for redirected content retrieved by the client out of band relative to a virtual channel such as the Internet. The network resource allocation rules may differ for different types of resources accessed. The device may also control a delivery agent on the server to modify communication sessions established through the virtual channels based on network conditions.

Abstract: The present invention is concerned with novel deuterated Angiotensin-Converting Enzyme-2 (ACE-2) inhibitors of general structural formula I, their optically active enantiomers and diastereoisomers, and pharmaceutical salts and compositions thereof, as well as combination therapies which include compounds of the present invention, These compounds have high potency and selectivity for Angiotensin-Converting Enzyme-2 (ACE-2) inhibition, and are useful in the treatment of infectious respiratory diseases including the pandemic disease Covid-19, Severe Acute Respiratory Syndrome (SARS-CoV-2), Severe Acute Respiratory Syndrome (SARS-CoV), and other diseases caused by coronaviruses.

Abstract: Virtual application and desktop delivery may be optimized by supplying application metadata and user intent to the device between a client and a server hosting resources for the delivery. The data packets used to deliver the virtual application or desktop may be also tagged with references to the application. By supplying the metadata and tagging packets with the metadata, an intermediary network device may provide streams of data packets at the target QoS. In addition, the device may apply network resource allocation rules (e.g., firewalls and QoS configuration) for redirected content retrieved by the client out of band relative to a virtual channel such as the Internet. The network resource allocation rules may differ for different types of resources accessed. The device may also control a delivery agent on the server to modify communication sessions established through the virtual channels based on network conditions.

Abstract: The present invention is concerned with deuterium-enriched substituted phenoxy-(3, 4-methylenedioxy)phenylacetic acid and acylsulfonamide derivatives of general structural formula I, their optically active or pure enantiomers and diastereomers, and pharmaceutical salts thereof, These compounds have selective antagonist activity for endothelin receptors or both endothelin and angiotensin II receptors, and are useful in the treatment of diseases mediated by endothelin and angiotensin-II and their receptors.

Abstract: Systems and methods for multi-links software-defined wide area network (SD-WAN) using phone mobile hotspots include a network device that receives, from a client, a request to establish a connection with a data source. The network device may select, responsive to receiving the request, a connection between the network device and one of the first registered cellular device or the second registered cellular device via which the network device is to transmit network traffic corresponding to the request, the first registered cellular device and the second registered cellular device registered with the network device and having a respective cellular connection. The network device may transmit network traffic corresponding to the request from the client via the connection to the data source.

Abstract: A method of image processing includes receiving a first image of human skin. The first image corresponds to a first, uniform broadband illumination condition. The method also includes receiving a second image which has the same field of view and contents as the first image. The second image corresponds to a second illumination condition which comprises a uniform narrowband illumination condition. The method also includes processing the first and second images to fit parameter maps for a spectral bidirectional scattering surface reflectance distribution function skin model. The parameter maps include a modelled melanin concentration, a modelled haemoglobin concentration, a modelled melanin blend-type fraction and a modelled epidermal haemoglobin fraction. At least three of the parameter maps are independent.

Abstract: Virtual application and desktop delivery may be optimized by supplying application metadata and user intent to the device between a client and a server hosting resources for the delivery. The data packets used to deliver the virtual application or desktop may be also tagged with references to the application. By supplying the metadata and tagging packets with the metadata, an intermediary network device may provide streams of data packets at the target QoS. In addition, the device may apply network resource allocation rules (e.g., firewalls and QoS configuration) for redirected content retrieved by the client out of band relative to a virtual channel such as the Internet. The network resource allocation rules may differ for different types of resources accessed. The device may also control a delivery agent on the server to modify communication sessions established through the virtual channels based on network conditions.

Abstract: The present invention is concerned with novel deuterated Angiotensin-Converting Enzyme-2 (ACE-2) inhibitors of general structural formula I, their optically active enantiomers and diastereoisomers, and pharmaceutical salts and compositions thereof, as well as combination therapies which include compounds of the present invention, These compounds have high potency and selectivity for Angiotensin-Converting Enzyme-2 (ACE-2) inhibition, and are useful in the treatment of infectious respiratory diseases including the pandemic disease Covid-19, Severe Acute Respiratory Syndrome (SARS-CoV-2), Severe Acute Respiratory Syndrome (SARS-CoV), and other diseases caused by coronaviruses.

Abstract: A method of image processing includes receiving a first image of human skin. The first image corresponds to a first, uniform broadband illumination condition. The method also includes receiving a second image which has the same field of view and contents as the first image. The second image corresponds to a second illumination condition which comprises a uniform narrowband illumination condition. The method also includes processing the first and second images to fit parameter maps for a spectral bidirectional scattering surface reflectance distribution function skin model. The parameter maps include a modelled melanin concentration, a modelled haemoglobin concentration, a modelled melanin blend-type fraction and a modelled epidermal haemoglobin fraction. At least three of the parameter maps are independent.

Abstract: Systems and methods for multi-links software-defined wide area network (SD-WAN) using phone mobile hotspots include a network device that receives, from a client, a request to establish a connection with a data source. The network device may select, responsive to receiving the request, a connection between the network device and one of the first registered cellular device or the second registered cellular device via which the network device is to transmit network traffic corresponding to the request, the first registered cellular device and the second registered cellular device registered with the network device and having a respective cellular connection. The network device may transmit network traffic corresponding to the request from the client via the connection to the data source.

Abstract: Embodiments of the present disclosure describe a system and method for dynamically duplicating network packets onto a reliable link. Network devices can be connected by a primary link and by a secondary link. As the network quality of the first link degrades, the system can adaptively duplicate network packets onto the second link. As a high priority link, the secondary link can have less total bandwidth when compared to the primary link. Accordingly, all the traffic traversing the primary link may not be able to be duplicated onto the secondary link to preserve network reliability when the quality of the first link degrades. The present solution can effectively manage the bandwidth of the secondary link and set duplication rates that control the duplication of the packets onto the secondary link.

Abstract: Virtual application and desktop delivery may be optimized by supplying application metadata and user intent to the device between a client and a server hosting resources for the delivery. The data packets used to deliver the virtual application or desktop may be also tagged with references to the application. By supplying the metadata and tagging packets with the metadata, an intermediary network device may provide streams of data packets at the target QoS. In addition, the device may apply network resource allocation rules (e.g., firewalls and QoS configuration) for redirected content retrieved by the client out of band relative to a virtual channel such as the Internet. The network resource allocation rules may differ for different types of resources accessed. The device may also control a delivery agent on the server to modify communication sessions established through the virtual channels based on network conditions.

Abstract: Virtual application and desktop delivery may be optimized by supplying application metadata and user intent to the device between a client and a server hosting resources for the delivery. The data packets used to deliver the virtual application or desktop may be also tagged with references to the application. By supplying the metadata and tagging packets with the metadata, an intermediary network device may provide streams of data packets at the target QoS. In addition, the device may apply network resource allocation rules (e.g., firewalls and QoS configuration) for redirected content retrieved by the client out of band relative to a virtual channel such as the Internet. The network resource allocation rules may differ for different types of resources accessed. The device may also control a delivery agent on the server to modify communication sessions established through the virtual channels based on network conditions.

Abstract: Virtual application and desktop delivery may be optimized by supplying application metadata and user intent to the device between a client and a server hosting resources for the delivery. The data packets used to deliver the virtual application or desktop may be also tagged with references to the application. By supplying the metadata and tagging packets with the metadata, an intermediary network device may provide streams of data packets at the target QoS. In addition, the device may apply network resource allocation rules (e.g., firewalls and QoS configuration) for redirected content retrieved by the client out of band relative to a virtual channel such as the Internet. The network resource allocation rules may differ for different types of resources accessed. The device may also control a delivery agent on the server to modify communication sessions established through the virtual channels based on network conditions.

Abstract: Disclosed embodiments process network traffic according to user feedback. At least one intermediary between a client and a server on a network may process network traffic of a session established between the client and the server. The at least one intermediary may intercept a message from the client identifying a level of quality of experience (QoE) indicated by a user based on the network traffic. The at least one intermediary may determine, in response to the intercepted message, that the level of the QoE is below a threshold, and a predefined action to improve a condition of the network causing the identified level of QoE. The at least one intermediary may change, according to the determination, the processing of the network traffic by taking the predefined action.

Abstract: Embodiments of the present disclosure describe a system and method for dynamically duplicating network packets onto a reliable link. Network devices can be connected by a primary link and by a secondary link. As the network quality of the first link degrades, the system can adaptively duplicate network packets onto the second link. As a high priority link, the secondary link can have less total bandwidth when compared to the primary link. Accordingly, all the traffic traversing the primary link may not be able to be duplicated onto the secondary link to preserve network reliability when the quality of the first link degrades. The present solution can effectively manage the bandwidth of the secondary link and set duplication rates that control the duplication of the packets onto the secondary link.

Abstract: Embodiments of the present disclosure describe a system and method for dynamically duplicating network packets onto a reliable link. Network devices can be connected by a primary link and by a secondary link. As the network quality of the first link degrades, the system can adaptively duplicate network packets onto the second link. As a high priority link, the secondary link can have less total bandwidth when compared to the primary link. Accordingly, all the traffic traversing the primary link may not be able to be duplicated onto the secondary link to preserve network reliability when the quality of the first link degrades. The present solution can effectively manage the bandwidth of the secondary link and set duplication rates that control the duplication of the packets onto the secondary link.

Abstract: A transmission includes input and output shafts, a hybrid module coupled to the input shaft and a gearbox coupled to the module and output shaft. The hybrid module includes an electric motor under driven by a gearset; a disconnect clutch coupled to the gearset and selectively to the input shaft; a launch clutch coupled to the disconnect clutch and selectively to a module output; and a vibration absorber coupled with the launch clutch. The gearbox includes three gearsets and five torque transmitting devices operable to generate six forward speeds and reverse. One torque transmitting device is a clutch brake applied with a piston that reaches over a park gear, and another one is a selectable one way clutch. Two of the torque transmitting devices are rotating clutches that are radially stacked. The transmission includes an electric only mode, a hybrid mode and a battery charging mode.