Abstract: A synthetic peptide modeled on the IRCX binding area of NHE3, is a competitive inhibitor of the IRCX and both stimulates basal NHE3 activity and prevents elevated Ca2+ and cAMP inhibition of NHE3. Methods of its preparation and use in the prevention and/or treatment of gastrointestinal disease, such as diarrhea are provided.

Abstract: A synthetic peptide modeled on the IRCX binding area of NHE3, is a competitive inhibitor of the IRCX and both stimulates basal NHE3 activity and prevents elevated Ca2+ and cAMP inhibition of NHE3. Methods of its preparation and use in the prevention and/or treatment of gastrointestinal disease, such as diarrhea are provided.

Abstract: A soldering tool (1) comprising a main housing (2) within which is located a fuel gas reservoir (4). A soldering body member (5) terminates in a rearwardly extending combustion chamber (11) within which is located a gas catalytic combustion element (14). A gas/air mixture is delivered through a jet outlet (21) where it is initially burnt with a flame in a flame combustion chamber (24) for raising the catalytic combustion element (14) to its ignition temperature. A piezoelectric ignition element (50) provides a spark across a spark gap (56) adjacent an electrode (55) for igniting the gas/air mixture to burn with a flame. An interrupt member (67) located downstream of a nozzle bore (28) temporarily interrupts the flow of fuel gas to the jet outlet (21) for extinguishing the flame after the catalytic combustion element (14) has been raised to its ignition temperature. A slidable actuator member (60) in the housing (2) sequentially operates the piezoelectric ignition element (50) and the interrupt member (67).

Abstract: A gas powered heating tool comprises a handle and a head which comprises a soldering tool element. Gas from a reservoir in the handle is delivered through a gas supply pipe to a combustion chamber where it is converted to heat by a catalytic heating element for heating the tool element. A nozzle orifice in a nozzle delivers a jet of gas through the gas supply pipe. The gas supply pipe conducts heat from the combustion chamber to a heat transfer member which in turn conducts heat to the nozzle to prevent freezing of gas in the nozzle orifice. Heat is also conducted to gas supply control means in the handle to prevent gas freezing.