Patents by Inventor Damian Francis John Purcell

Damian Francis John Purcell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR INHIBITING HIV TRANSMISSION
    Publication number: 20200140529
    Abstract: The present invention provides methods and compositions useful in the field of medicine, and particularly in the treatment of viral infections. More particularly, the invention relates to the use of methods and compositions for the inhibition of human immunodeficiency virus (HIV) transmission.
    Type: Application
    Filed: November 1, 2019
    Publication date: May 7, 2020
    Inventor: Damian Francis John Purcell
  • ACTIVATORS OF HIV LATENCY
    Publication number: 20190330167
    Abstract: The present invention relates to novel compounds which active HIV expression in latently infected cells. More particularly, the invention relates to pharmaceutical compositions comprising the novel compounds and their use in activating HIV expression in latently infected cells. Further still, the invention relates to pharmaceutical compositions comprising the novel compounds in combination with anti-HIV therapy compounds and their use in treating HIV infection in both animals and humans. The invention further provides means for preparing the compounds.
    Type: Application
    Filed: June 21, 2017
    Publication date: October 31, 2019
    Inventors: Brad SLEEBS, Damian Francis John PURCELL, Jonathan JACOBSON, Sharon LEWIN, William NGUYEN
  • METHODS AND COMPOSITIONS FOR INHIBITING HIV TRANSMISSION
    Publication number: 20180134768
    Abstract: The present invention provides methods and compositions useful in the field of medicine, and particularly in the treatment of viral infections. More particularly, the invention relates to the use of methods and compositions for the inhibition of human immunodeficiency virus (HIV) transmission.
    Type: Application
    Filed: November 20, 2017
    Publication date: May 17, 2018
    Applicant: Reef Pharmaceuticals Pty Ltd
    Inventor: Damian Francis John PURCELL
  • METHODS AND COMPOSITIONS FOR INHIBITING HIV TRANSMISSION
    Publication number: 20130022619
    Abstract: The present invention provides methods and compositions useful in the field of medicine, and particularly in the treatment of viral infections. More particularly, the invention relates to the use of methods and compositions for the inhibition of human immunodeficiency virus (HIV) transmission.
    Type: Application
    Filed: April 11, 2011
    Publication date: January 24, 2013
    Inventors: Grant Thomas Rawlin, Damian Francis John Purcell, Robert John Center, Marit Kramski, Roy Michael Robins-Browne, Gottfried Lichti
  • Nucleic acid construct encoding a processing component derived from the N-terminal region of the hepatitis virus ORF2, and an antigenic polypeptide
    Patent number: 7341723
    Abstract: A method for enhancing an immune response to a nucleic acid vaccine comprising administering to an animal a nucleic acid construct encoding a fusion protein comprising a processing component and an antigenic polypeptide of interest wherein said processing component provides heterogeneous processing of the antigenic polypeptide when the nucleic acid construct is expressed in a host cell and a resulting enhancement of the immune response. The processing component is derived from an N-terminal portion of PORF2 of Hepatitis E virus.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: March 11, 2008
    Assignee: Macfarlane Burnet Institute for Medical Research and Public Health Ltd.
    Inventors: Fan Li, David Andrew Anderson, Damian Francis John Purcell
  • Nucleic acid construct encoding a processing component derived from the N-terminal region of the hepatitis virus ORF2, and an antigenic polypeptide
    Publication number: 20030158138
    Abstract: A method for enhancing an immune response to a nucleic acid vaccine comprising administering to an animal a nucleic acid construct encoding a fusion protein comprising a processing component and an antigenic polypeptide of interest wherein said processing component provides heterogeneous processing of the antigenic polypeptide when the nucleic acid construct is expressed in a host cell and a resulting enhancement of the immune response. The processing component is derived from an N-terminal portion of PORF2 of Hepatitis E virus.
    Type: Application
    Filed: September 27, 2002
    Publication date: August 21, 2003
    Inventors: Fan Li, David Andrew Anderson, Damian Francis John Purcell
  • CD46 variants
    Patent number: 5846715
    Abstract: CD46 (membrane cofactor protein) is a family of human cell surface glycoprotein with cofactor activity for factor I mediated cleavage of complement components C3b and C4b. Disclosed are novel nucleic acid sequences arising from splice variants or derivatives thereof of the structural gene encoding the family of proteins. From these sequences recombinant derived proteins and antibodies thereto can be produced. The proteins can resemble native CD46 isoforms or comprise new permutations of exons within the structural gene. The nucleic acids, proteins and antibodies have utility as probes, diagnostic reagents and therapeutic agents.
    Type: Grant
    Filed: September 14, 1995
    Date of Patent: December 8, 1998
    Assignee: The Austin Research Institute
    Inventors: Damian Francis John Purcell, Sarah May Russell, Ian Farquar Campbell McKenzie