Patents by Inventor Damian Kusmirek

Damian Kusmirek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PRODUCTION OF (1R,2S,5R)-1-AMINO-5-[2-(DIHYDROXYBORANYL)ETHYL]-2-[(DIMETHYLAMINO)METHYL]-CYCLOHEXANE-1-CARBOXYLIC ACID
    Publication number: 20240336635
    Abstract: The present invention relates to a process for the preparation of (1R,2S,5R)-1-amino-5-[2-(dihydroxyboranyl)ethyl]-2-[(dimethylamino)methyl]cyclohexane-1-carboxylic acid in anhydrous crystalline form A. The present invention further relates to methyl (1R,2R,4R)-2-acetamido-2-(tert-butylcarbamoyl)-4-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)-cyclohexane-1-carboxylate which is the intermediate in this process.
    Type: Application
    Filed: April 3, 2024
    Publication date: October 10, 2024
    Inventors: Marta Magdycz, Lukasz Mucha, Damian Kusmirek, Kamil Lisiecki, Marek Masnyk, Piotr Pomaranski, Magdalena Tyszkiewicz, Stanislaw Pikul, Elzbieta Sobolewska
  • YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS
    Publication number: 20230348516
    Abstract: This invention is related to novel inhibitors of chitinase-like protein YKL-40 and their therapeutic applications. Such YKL-40 inhibitors are of use as therapeutic agents for the treatment a variety of diseases and disorders, including cancers, inflammation, and pulmonary diseases.
    Type: Application
    Filed: April 28, 2023
    Publication date: November 2, 2023
    Inventors: Wojciech Czestkowski, Marzena Mazur, Przemyslaw Wanat, Gleb Andryianau, Piotr Niedziejko, Michal Kowalski, Mariusz Marek Gruza, Kamil Lisiecki, Piotr Pomaransk, Damian Kusmirek, Diana Papiernik, Katarzyna Drzewicka, Katarzyna Piwowar, Katarzyna Krysztofiak, Jacek Olczak, Adam Golebiowski, Lukasz Krzeminski, Agnieszka Bartoszewicz