Patents by Inventor Damian Mark Grainger

Damian Mark Grainger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of sphingosine-1-phosphate receptor agonist
    Patent number: 11465977
    Abstract: Industrially viable and advantageous processes for the preparation of Ozanimod are described. The invention also discloses the intermediates obtained in the process.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: October 11, 2022
    Assignee: QUÍMICA SINTÉTICA, S.A.
    Inventors: Giuseppe Barreca, Luca Carcone, Maurizio Taddei, Damian Mark Grainger, Samantha Louise Staniland, Claudio Cianferotti, Giovanni Marras
  • PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST
    Publication number: 20220033365
    Abstract: Industrially viable and advantageous processes for the preparation of Ozanimod are described. The invention also discloses the intermediates obtained in the process.
    Type: Application
    Filed: September 25, 2019
    Publication date: February 3, 2022
    Applicant: QUÍMICA SINTÉTICA, S.A.
    Inventors: Giuseppe BARRECA, Luca CARCONE, Maurizio TADDEI, Damian Mark GRAINGER, Samantha Louise STANILAND, Claudio CIANFEROTTI, Giovanni MARRAS
  • Process for hydrogenating ketones in the presence of Ru(II) catalysts
    Patent number: 10406514
    Abstract: The present invention relates to a process for hydrogenating a substrate including a carbon-heteroatom double bond, the process including the step of reacting the substrate with hydrogen gas in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst is a complex of formula (I): R1-10, A and Hal are as defined in the specification. The present invention also provides processes for the preparation of the complex of formula (I) and intermediates thereof.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: September 10, 2019
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Alan Dyke, Damian Mark Grainger, Jonathan Alan Medlock, Hans Guenter Nedden, Jacques Jean Marie Le Paih, Stephen James Roseblade, Andreas Seger, Vilvanathan Sivakumar, Antonio Zanotti-Gerosa
  • Process For Hydrogenating Ketones In The Presence Of RU(II) Catalysts
    Publication number: 20180290133
    Abstract: The present invention relates to a process for hydrogenating a substrate including a carbon-heteroatom double bond, the process including the step of reacting the substrate with hydrogen gas in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst is a complex of formula (I): R1-10, A and Hal are as defined in the specification. The present invention also provides processes for the preparation of the complex of formula (I) and intermediates thereof.
    Type: Application
    Filed: March 27, 2018
    Publication date: October 11, 2018
    Inventors: Alan DYKE, Damian Mark GRAINGER, Jonathan Alan MEDLOCK, Hans Guenter NEDDEN, Jacques Jean Marie LE PAIH, Stephen James ROSEBLADE, Andreas SEGER, Vilvanathan SIVAKUMAR, Antonio ZANOTTI-GEROSA
  • PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS
    Publication number: 20160271599
    Abstract: The present invention relates to a process for hydrogenating a substrate including a carbon-heteroatom double bond, the process including the step of reacting the substrate with hydrogen gas in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst is a complex of formula (I): R1-10, A and Hal are as defined in the specification. The present invention also provides processes for the preparation of the complex of formula (I) and intermediates thereof.
    Type: Application
    Filed: May 27, 2016
    Publication date: September 22, 2016
    Inventors: Alan Dyke, Damian Mark Grainger, Jonathan Alan Medlock, Hans Guenter Nedden, Jacques Jean Marie Le Paih, Stephen James Roseblade, Andreas Seger, Vilvanathan Sivakumar, Antonio Zanotti-Gerosa
  • Process for hydrogenating ketones in the presence of Ru(II) catalysts
    Patent number: 9416100
    Abstract: The present invention relates to a process for hydrogenating a substrate comprising a carbon-heteroatom double bond, the process comprising the step of reacting the substrate with hydrogen gas in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst is a complex of formula (I): R1-10, A and Hal are as defined in the specification. The present invention also provides processes for the preparation of the complex of formula (I) and intermediates thereof.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: August 16, 2016
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Alan Dyke, Damian Mark Grainger, Jonathan Alan Medlock, Hans Guenter Nedden, Jacques Jean Marie Le Paih, Stephen James Roseblade, Andreas Seger, Vilvanathan Sivakumar, Antonio Zanotti-Gerosa
  • Ruthenium complexes comprising paracyclophane and carbonyl ligands, and their use as catalyst
    Patent number: 8940917
    Abstract: The present invention relates to the ruthenium complexes comprising paracyclophane and carbonyl ligands, methods for the preparation thereof and uses of the complexes in isomerization, hydrogenation, transfer hydrogenation, hydroformylation and carbonylation reactions.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: January 27, 2015
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Damian Mark Grainger, Hans Guenter Nedden, Stephen James Roseblade
  • PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS
    Publication number: 20140357903
    Abstract: The present invention relates to a process for hydrogenating a substrate including a carbon-heteroatom double bond, the process including the step of reacting the substrate with hydrogen gas in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst is a complex of formula (I): R1-10, A and Hal are as defined in the specification. The present invention also provides processes for the preparation of the complex of formula (I) and intermediates thereof.
    Type: Application
    Filed: August 13, 2014
    Publication date: December 4, 2014
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Alan DYKE, Damian Mark GRAINGER, Jonathan Alan MEDLOCK, Hans Guenter NEDDEN, Jacques Jean Marie LE PAIH, Stephen James ROSEBLADE, Andreas SEGER, Vilvanathan SIVAKUMAR, Antonio ZANOTTI-GEROSA
  • RUTHENIUM COMPLEXES COMPRISING PARACYCLOPHANE AND CARBONYL LIGANDS, AND THEIR USE AS CATALYST
    Publication number: 20140155642
    Abstract: The present invention relates to the ruthenium complexes comprising paracyclophane and carbonyl ligands, methods for the preparation thereof and uses of the complexes in isomerisation, hydrogenation, transfer hydrogenation, hydroformylation and carbonylation reactions.
    Type: Application
    Filed: March 16, 2012
    Publication date: June 5, 2014
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Damian Mark Grainger, Hans Guenter Nedden, Stephen James Roseblade
  • PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS
    Publication number: 20120123142
    Abstract: The present invention relates to a process for hydrogenating a substrate comprising a carbon-heteroatom double bond, the process comprising the step of reacting the substrate with hydrogen gas in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst is a complex of formula (I): R1-10, A and Hal are as defined in the specification. The present invention also provides processes for the preparation of the complex of formula (I) and intermediates thereof.
    Type: Application
    Filed: March 17, 2010
    Publication date: May 17, 2012
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Alan Dyke, Damian Mark Grainger, Jonathan Alan Medlock, Hans Guenter Nedden, Jacques Jean Marie Le Paih, Stephen James Roseblade, Andreas Seger, Vilvanathan Sivakumar, Antonio Zanotti-Gerosa