Patents by Inventor Damien Fraysse

Damien Fraysse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases
    Patent number: 7795259
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinase of the following formula: or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
    Type: Grant
    Filed: November 22, 2005
    Date of Patent: September 14, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Daniel Robinson, Damien Fraysse, Andrew Miller
  • Aminopyrimidines useful as kinase inhibitors
    Patent number: 7767672
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: August 3, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Michael Mortimore, Chris Davis, Dean Boyall, Simon Everitt, Daniel Robinson, Sharn Ramaya, Damien Fraysse, John Studley, Andrew Miller, Michael O'Donnell, Alistair Rutherford, Joanne Pinder
  • AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS
    Publication number: 20090181938
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Application
    Filed: March 25, 2009
    Publication date: July 16, 2009
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Michael Mortimore, Damien Fraysse, Chris Davis, Michael O'Donnell, Simon Everitt, Daniel Robinson, Joanne Pinder, Andrew Miller
  • Azaindoles useful as inhibitors of JAK and other protein kinases
    Publication number: 20090176763
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: November 19, 2008
    Publication date: July 9, 2009
    Inventors: Francesco Salituro, Luc Farmer, Randy Bethiel, Edmund Harrington, Jeremy Green, John Court, Jon Come, David Lauffer, Alex Aronov, Hayley Binch, Dean Boyall, Jean-Damien Charrier, Simon Everitt, Damien Fraysse, Michael Mortimore, Francoise Pierard, Daniel Robinson, Jian Wang, Joanne Pinder, Tiansheng Wang, Albert Pierce
  • KINASE INHIBITORS
    Publication number: 20090124602
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
    Type: Application
    Filed: August 7, 2008
    Publication date: May 14, 2009
    Inventors: FRANCOIS MALTAIS, GUY BEMIS, TIANSHENG WANG, JUAN-MIGUEL JIMENEZ, RONALD KNEGTEL, CHRIS DAVIS, DAMIEN FRAYSSE
  • Aminopyrimidines useful as kinase inhibitors
    Patent number: 7528142
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: May 5, 2009
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Michael Mortimore, Damien Fraysse, Chris Davis, Michael O'Donnell, Simon Everitt, Daniel Robinson, Joanne Pinder, Andrew Miller
  • Azaindoles useful as inhibitors of JAK and other protein kinases
    Patent number: 7507826
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: March 24, 2009
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Francesco Salituro, Luc Farmer, Randy Bethiel, Edmund Harrington, Jeremy Green, John Court, Jon Come, David Lauffer, Alex Aronov, Hayley Binch, Dean Boyall, Jean-Damien Charrier, Simon Everitt, Damien Fraysse, Michael Mortimore, Francoise Pierard, Daniel Robinson, Jian Wang, Joanne Pinder, Tiansheng Wang, Albert Pierce
  • Aminopyrimidines useful as kinase inhibitors
    Publication number: 20080032963
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Application
    Filed: November 3, 2006
    Publication date: February 7, 2008
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Michael Mortimore, Damien Fraysse, Alistair Rutherford
  • Aminopyrimidines useful as kinase inhibitors
    Publication number: 20070259869
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Application
    Filed: November 3, 2006
    Publication date: November 8, 2007
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Michael Mortimore, Chris Davis, Dean Boyall, Simon Everitt, Daniel Robinson, Sharn Ramaya, Damien Fraysse, John Studley, Andrew Miller, Michael O'Donnell, Alistair Rutherford, Joanne Pinder
  • Aminopyrimidines useful as kinase inhibitors
    Publication number: 20070249031
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Application
    Filed: November 3, 2006
    Publication date: October 25, 2007
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Michael Mortimore, Damien Fraysse, Chris Davis, Michael O'Donnell, Simon Everitt, Daniel Robinson, Joanne Pinder, Andrew Miller
  • Aminopyrimidines useful as kinase inhibitors
    Publication number: 20070179125
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the inventions.
    Type: Application
    Filed: November 16, 2006
    Publication date: August 2, 2007
    Inventors: Damien Fraysse, Andrew Miller, Daniel Robinson, Joanne Pinder
  • Azaindoles useful as inhibitors of JAK and other protein kinases
    Publication number: 20070043063
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: March 30, 2005
    Publication date: February 22, 2007
    Inventors: Francesco Salituro, Luc Farmer, Randy Bethiel, Edmund Harrington, Jeremy Green, John Court, Jon Come, David Lauffer, Alex Aronov, Hayley Binch, Dean Boyall, Jean-Damien Charrier, Simon Everitt, Damien Fraysse, Michael Mortimore, Francoise Pierard, Daniel Robinson, Jian Wang, Joanne Pinder, Tiansheng Wang
  • Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases
    Publication number: 20060258662
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
    Type: Application
    Filed: November 22, 2005
    Publication date: November 16, 2006
    Inventors: Hayley Binch, Daniel Robinson, Damien Fraysse, Andrew Miller
  • Diaminotriazole compounds useful as inhibitors of protein kinases
    Publication number: 20060166936
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention, processes for preparing the compounds and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 31, 2005
    Publication date: July 27, 2006
    Inventors: Hayley Binch, Damien Fraysse, Daniel Robinson