Patents by Inventor Damien MORGER

Damien MORGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FC-MODIFIED BIOLOGICALS FOR LOCAL DELIVERY TO COMPARTMENTS, IN PARTICULAR TO THE CNS
    Publication number: 20220204633
    Abstract: A polypeptide comprising a crystallizable fragment (Fe) region of IgG for use in prevention or treatment of a disease, in particular of a disease affecting the central nervous system. The polypeptide is administered locally to compartments, in particular to the central nervous system. The Fe region comprises the mutations I253N and H435Q and an H at position 310 resulting in reduced affinity to the neonatal Fe receptor (FeRn), resulting in an increased brain to serum concentration of the polypeptide.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 30, 2022
    Inventors: Johannes vom BERG, Damien MORGER, Linda SCHELLHAMMER, Michal BEFFINGER, Thorsten BUCH
  • Fc-MODIFIED BIOLOGICALS FOR LOCAL DELIVERY TO COMPARTMENT, IN PARTICULAR TO THE CNS
    Publication number: 20220195051
    Abstract: A polypeptide comprising a crystallizable fragment (Fc) region of IgG for use in prevention or treatment of a disease, particularly a disease affecting the central nervous system. The polypeptide is administered locally to the affected compartment, in particular to the central nervous system. The Fc region bears a modification resulting in reduced affinity to the neonatal Fc receptor (FcRn), resulting in an increased brain to serum concentration of the polypeptide.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 23, 2022
    Inventors: Johannes vom BERG, Damien MORGER, Linda SCHELLHAMMER, Michal BEFFINGER, Thorsten BUCH