Abstract: A method for quantifying the balance of an individual recording, on a memory, at least one statokinesigram of the individual obtained from a platform comprising pressure and/or force sensors; extracting, by a processor and from the at least one statokinesigram of the individual recorded on the memory, values of at least one position trajectory parameter of the pressure center and values of at least one stability trajectory parameter of the pressure center; determining, by the processor, the value of a plurality of quantifiers, from the values of the trajectory parameters extracted; comparing, by the processor, said values of the plurality of quantifiers with the values of the same quantifiers obtained from reference statokinesigrams; and determining, by the processor, said value representative of the balance of the individual at the end of the comparison.

Abstract: The present invention presents a device for calculating, during one step or each successive step of the gait of a subject, the push-off P0 of the subject, which is the power per kilogram released by the ankle push-off moment, which comprises: at least one inertial measurement unit (1A, 1B) on one foot of the subject, the inertial measurement unit (1A, 1B) having: at least one accelerometer to measure the vertical and antero-posterior accelerations and/or at least one gyroscope to measure the medic-lateral angular speed data {acute over (?)} during the gait, storage and calculation means (2A) connected to the Inertial measurement unit (1A, 1B), configured to calculate: for the foot, and for the step or each successive step of the gait:—the time of the heel-off and the time of the toe-off,—the push-off P0, by the Euler's equation stating that the sum of moments acting on the foot taken as a rigid body, being equal to the rate of change of the angular momentum of the foot, with the calculation of the push-off P0

Abstract: A device for analyzing the regularity and symmetry of a sequence of N gait or running cycles of a person, comprising sensors for measuring raw time signals of a physical movement variable of a body segment, a processing unit connected to the sensors for measuring and configured to separate the raw time signals into distinct time signals Ci, the Ci series being associated with a given gait or running cycle i of the person, to calculate at least one similarity coefficient between the signal Ci associated with gait or running cycle i and another signal Cj associated with a gait or running cycle j of the person. A display is configured to display the matrix M(i,j) with each value of the similarity coefficient shown in the matrix M(i,j) in color to form a graduated color scale indicating the similarity between the gait or running cycles i and j.

Abstract: A method for quantifying the balance of an individual includes segmenting, as a function of time, a statokinesigram(s) of an individual so as to generate several statokinesigram portions; extracting, from the statokinesigram portions, values of at least one trajectory parameter; determining the value of at least two quantifiers, from the values of trajectory parameters extracted in the extraction step, for each of the statokinesigram portions generated in the segmentation step; and determining said value representative of the balance of the individual from the values of the quantifiers of each of the statokinesigram portions. The method may be implemented by a processor and memory.

Abstract: A method is provided for characterising a gait comprising steps of: receiving a signal measuring the movement of a target subject measured beforehand; comparing (204) at least one section of the measuring signal with a plurality of reference signals, the plurality of reference signals comprising at least one movement signal measured beforehand on a reference subject different from the target subject, each comparison of the measuring signal with a reference signal producing a similarity coefficient representative of a probability of similarity between the compared signals; and selecting (208) at least one local maximum of interest among the similarity coefficients produced, wherein the plurality of reference signals comprises at least one movement signal measured beforehand on a reference subject afflicted with a gait disorder, and at least one movement signal measured beforehand on a healthy reference object.

Abstract: The present invention relates to a bacteriophage strain capable of producing a lytic infection in the Escherichia coli ST131-025b:H4 clone. The burden of ST131-025b:H4 Escherichia coli clonal complex in human community and hospital-acquired infections is increasing worldwide, going along with a worrying and growing resistance to betalactams and fluoroquinolones. Bacteriophage LM33_P1 infects exclusively (100% specificity) 025b E. coli strains with 70% coverage on the two major antibiotic resistant pandemic clonal complexes ST131-025b:H4 and ST69-025b. The inventors evaluated the in vivo activity of bacteriophage LM33_P1 using three different extraintestinal virulence murine models and showed that it infects bacteria in several organs.

Abstract: The invention relates to a method for quantifying the balance of an individual to obtain a value representative of the balance of said individual, said method being implemented by a device comprising at least one data processing module, one storage means, and one classification module, said method comprising in particular the following steps: segmenting, as a function of time, the statokinesigram(s) of an individual so as to generate several statokinesigram portions, extracting, from the statokinesigram portions, values of at least one trajectory parameter, determining the value of at least two quantifiers, from the values of trajectory parameters extracted in the extraction step for each of the statokinesigram portions generated in the segmentation step, and determining said value representative of the balance of the individual from the values of the quantifiers of each of the statokinesigram portions.

Abstract: The present invention relates to a method for preventing Gram-negative bacterial colonization of an oropharyngeal material, the said method comprising bringing into contact a composition comprising a cranberry-derived proanthocyanidin extract on at least a part of the surface area of the said material.

Abstract: The invention relates to a method for quantifying the balance of an individual to obtain a value representative of the balance of said individual, said method being implemented by a device comprising at least one data processing module connected to a storage means and said method comprising: a) a step of recording, on the storage means, at least one statokinesigram of the individual obtained from a platform comprising pressure and/or force sensors, b) a step of extracting, by the data processing module and from the one or more statokinesigram(s) of the individual recorded on the storage means, values of at least one position trajectory parameter of the pressure center and values of at least one stability trajectory parameter of the pressure center, c) a step of determining, by the data processing module, the value of several quantifiers, from the values of the trajectory parameters extracted in step b), d) a step of comparing, by the data processing module, said values of several quantifiers with the value

Abstract: The present invention concerns a device 1 for analysing the regularity and symmetry of a sequence of N gait or running cycles of a person, comprising measurement sensors 2 for measuring raw time signals of a physical movement variable of a body segment, a processing unit connected to the measurement sensors 2 and having calculation and processing means set up to separate the raw time signals into distinct time signals Ci, the Ci series being associated with a given gait or running cycle i of the person, to calculate at least one similarity coefficient between the signal Ci associated with gait or running cycle i and another signal Cj associated with a gait or running cycle j of the same person, display means 4 connected to the processing unit and displaying the matrix M(i,j) with each value of the similarity coefficient shown in the matrix M(i,j) by a colour in a graduated colour scale to make it possible for the similarity between the gait or running cycles i and j to be seen with the naked eye.

Abstract: The present invention relates to a bacteriophage strain capable of producing a lytic infection in the Escherichia coli ST131-025b:H4 clone. The burden of STl31-025b:H4 Escherichia coli clonal complex in human community and hospital-acquired infections is increasing worldwide, going along with a worrying and growing resistance to betalactams and fluoroquinolones. Bacteriophage LM33_P1 infects exclusively (100% specificity) 025b E. coli strains with 70% coverage on the two major antibiotic resistant pandemic clonal complexes STI31-025b:H4 and ST69-025b. The inventors evaluated the in vivo activity of bacteriophage LM33_P1 using three different extraintestinal virulence murine models and showed that it infects bacteria in several organs.

Abstract: The present invention relates to methods and kits for the rapid detection of the Escherichia coli O25b-ST131 clone. The inventors have isolated a podoviridae bacteriophage (LM33_P1) infecting the E. coli strain LM33 isolated from ventilator associated pneumonia and which belongs to clone STI3I-025b. By testing different strains of E coli belonging to 129 others various distinct serotypes (including twelve O25a) the inventors found that bacteriophage LM33_P1 is able to infect exclusively O25b strains (none of non-O25b strains could be infected by LM33_P1). The inventors have determined that the specificity displayed by bacteriophage LM33_P1 to infect only 025b serotype strains is based on a very specific polypeptide (Gp17) used by LM33_P1 to attach the bacterial cell via LPS molecule. In particular, the present invention relates to a polypeptide comprising an amino acid sequence having at least 80% of identity with the amino acid sequence set forth in SEQ ID NO:1.

Abstract: A method is provided for characterising a gait comprising steps of: receiving a signal measuring the movement of a target subject measured beforehand; comparing (204) at least one section of the measuring signal with a plurality of reference signals, the plurality of reference signals comprising at least one movement signal measured beforehand on a reference subject different from the target subject, each comparison of the measuring signal with a reference signal producing a similarity coefficient representative of a probability of similarity between the compared signals; and selecting (208) at least one local maximum of interest among the similarity coefficients produced, wherein the plurality of reference signals comprises at least one movement signal measured beforehand on a reference subject afflicted with a gait disorder, and at least one movement signal measured beforehand on a healthy reference object.

Abstract: The present invention relates to a method for preventing Gram-negative bacterial colonization of an oropharyngeal material, the said method comprising bringing into contact a composition comprising a cranberry-derived proanthocyanidin extract on at least a part of the surface area of the said material.

Abstract: This invention relates to methods and compositions for the prevention or treatment of myelin disorders which involve modulating of Ulip/CRMP activity. In particular, a method for the prevention or treatment of myelin disorders is provided which comprises administering to a patient in need of such treatment a therapeutically effective amount of an agent which modulates Ulip/CRMP activity, and which can be a Ulip/CRMP protein, a nucleic acid coding for a Ulip/CRMP protein, an anti-sense sequence capable of specifically hybridizing with said nucleic acid, an antibody directed against the Ulip/CRMP protein, or an aptamer capable of binding said protein, and a pharmacologically acceptable carrier.