Abstract: A delivery system for delivering an implant having both a rigid portion and a flexible portion to a body lumen. The delivery system includes an outer tubular member and an inner tubular member slidably disposed within the lumen of the outer tubular member. The inner tubular member includes at least one opening positioned in a side wall adjacent to a distal end region. An expandable implant, including a rigid portion and a flexible portion, is disposed about the outer surface of the inner tubular member. A distal portion of a thread is wrapped around the flexible portion of the implant and configured to maintain the flexible portion in a radially collapsed configuration during delivery of the implant. A distal end region of the outer tubular member is disposed around the rigid portion of the implant to maintain the rigid portion in a radially collapsed configuration during delivery of the implant.

Abstract: A delivery system for delivering an implant having both a rigid portion and a flexible portion to a body lumen. The delivery system includes an outer tubular member and an inner tubular member slidably disposed within the lumen of the outer tubular member. The inner tubular member includes at least one opening positioned in a side wall adjacent to a distal end region. An expandable implant, including a rigid portion and a flexible portion, is disposed about the outer surface of the inner tubular member. A distal portion of a thread is wrapped around the flexible portion of the implant and configured to maintain the flexible portion in a radially collapsed configuration during delivery of the implant. A distal end region of the outer tubular member is disposed around the rigid portion of the implant to maintain the rigid portion in a radially collapsed configuration during delivery of the implant.

Abstract: A medical device may include a snare loop and an elastic member that connects at least two sides of the snare loop. The elastic member is configured to transition from an unexpanded state where the elastic member is in a plane of the snare loop to an expanded state where the elastic member is outside the plane of the snare loop. The snare loop has a same shape when the elastic member is in the unexpanded shape and the expanded shape.

Abstract: A delivery system for delivering an implant having both a rigid portion and a flexible portion to a body lumen. The delivery system includes an outer tubular member and an inner tubular member slidably disposed within the lumen of the outer tubular member. The inner tubular member includes at least one opening positioned in a side wall adjacent to a distal end region. An expandable implant, including a rigid portion and a flexible portion, is disposed about the outer surface of the inner tubular member. A distal portion of a thread is wrapped around the flexible portion of the implant and configured to maintain the flexible portion in a radially collapsed configuration during delivery of the implant. A distal end region of the outer tubular member is disposed around the rigid portion of the implant to maintain the rigid portion in a radially collapsed configuration during delivery of the implant.

Abstract: A medical device may include a snare loop and an elastic member that connects at least two sides of the snare loop. The elastic member is configured to transition from an unexpanded state where the elastic member is in a plane of the snare loop to an expanded state where the elastic member is outside the plane of the snare loop. The snare loop has a same shape when the elastic member is in the unexpanded shape and the expanded shape.

Abstract: An injectable composition for intravascular delivery of a therapeutic agent includes one or more first microspheres containing a first therapeutic agent, one or more second microspheres containing a second therapeutic agent, and a liquid carrier. The first microspheres includes a wall comprising a biodegradable polymer that encapsulates the first therapeutic agent and the second microspheres includes a wall comprising the biodegradable polymer that encapsulates the second therapeutic agent.

Abstract: An implantable medical device includes a body that has a flexible outer layer encapsulating a composition. The composition includes one or more first microspheres, one or more second microspheres, and a carrier. Each first microsphere includes a first therapeutic agent and a wall containing a first biodegradable polymer that encapsulates the first therapeutic agent. Each second microsphere includes a second therapeutic agent and a wall containing a biodegradable polymer that encapsulates the second therapeutic agent.