Patents by Inventor Damjan Sterk

Damjan Sterk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of triazolopyrimidine compounds
    Patent number: 9469614
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: October 18, 2016
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Borut Zupancic, Nenad Maras, Damjan Sterk
  • Synthesis of triazolopyrimidine compounds
    Patent number: 9278972
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: March 8, 2016
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Nenad Maras, Ivana Gazic Smilovic, Damjan Sterk
  • Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof
    Patent number: 9085538
    Abstract: The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: July 21, 2015
    Assignee: LEK PHARMACEUTICALS D.D.
    Inventors: Zdenko Casar, Damjan Sterk, Marko Jukic
  • Synthesis of Triazolopyrimidine Compounds
    Publication number: 20140371449
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.
    Type: Application
    Filed: December 20, 2012
    Publication date: December 18, 2014
    Applicant: Lek Pharmaceuticals d.d.
    Inventors: Nenad Maras, Ivana Gazic Smilovic, Damjan Sterk
  • Synthesis of Triazolopyrimidine Compounds
    Publication number: 20140256747
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
    Type: Application
    Filed: October 26, 2012
    Publication date: September 11, 2014
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Borut Zupancic, Nenad Maras, Damjan Sterk
  • Methods of synthesis of ?-aminobutyryl substituted compounds
    Patent number: 8765668
    Abstract: The present invention relates to process to prepare ?-aminobutyryl compounds having ?-amino acid core structural moieties and optionally having ?-phenyl and/or heterocyclic structural moieties. Such compounds are useful as key structure framework of modern drug chemistry.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: July 1, 2014
    Assignee: Lek Pharmaceuticals D.D.
    Inventors: Damjan Sterk, Matjaz Ustar, Marko Zlicar
  • Short synthesis of tolterodin, intermediates and metabolites
    Patent number: 8703996
    Abstract: A process is described for the preparation of intermediates which can be used for preparation of agents for urinary incontinence therapy, specifically to 2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol and its prodrugs.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: April 22, 2014
    Assignee: Lek Pharmaceuticals D.D.
    Inventor: Damjan Sterk
  • PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF STATINS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
    Publication number: 20140051854
    Abstract: The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.
    Type: Application
    Filed: July 25, 2011
    Publication date: February 20, 2014
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Zdenko Casar, Damjan Sterk, Marko Jukic
  • SHORT SYNTHESIS OF TOLTERODINE, INTERMEDIATES AND METABOLITES
    Publication number: 20130197082
    Abstract: A process is described for the preparation of intermediates which can be used for preparation of agents for urinary incontinence therapy, specifically to 2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol and its prodrugs.
    Type: Application
    Filed: March 8, 2011
    Publication date: August 1, 2013
    Applicant: Lek Pharmaceuticals D.D.
    Inventor: Damjan Sterk
  • NOVEL SYNTHETIC APPROACH TO beta-AMINOBUTYRYL SUBSTITUTED COMPOUNDS
    Publication number: 20130130974
    Abstract: The present invention relates to process to prepare ?-aminobutyryl compounds having ?-amino acid core structural moieties and optionally having ?-phenyl and/or heterocyclic structural moieties. Such compounds are useful as key structure framework of modern drug chemistry.
    Type: Application
    Filed: June 3, 2011
    Publication date: May 23, 2013
    Inventors: Damjan Sterk, Matjaz Ustar, Marko Zlicar
  • Form of a benzenesulfonamide derivative
    Patent number: 7868174
    Abstract: The present disclosure relates to an improved process for the preparation of enantiomerically enriched alcohols of Formula (I), from the corresponding ketone of Formula (II), by asymmetric transfer hydrogenation, using a hydrogen donor, catalyzed by a ruthenium or rhodium complex of an optically active N-sulfamoyl-1,2-diamine. R is as defined herein.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: January 11, 2011
    Assignee: Pliva-Istrazivanje I Razvoj d.o.o.
    Inventors: Amir Avdagic, Barbara Mohar, Damjan Sterk, Michel Stephan
  • Novel Form of a Benzenesulfonamide Derivative
    Publication number: 20080009629
    Abstract: The present disclosure relates to an improved process for the preparation of enantiomerically enriched alcohols of Formula (I), from the corresponding ketone of Formula (II), by asymmetric transfer hydrogenation, using a hydrogen donor, catalyzed by a ruthenium or rhodium complex of an optically active N-sulfamoyl-1,2-diamine. R is as defined herein.
    Type: Application
    Filed: July 21, 2005
    Publication date: January 10, 2008
    Applicant: Pliva-Istrazivanje I Razvoj d.o.o.
    Inventors: Amir Avdagic, Barbara Mohar, Damjan Sterk, Michel Stephan