Patents by Inventor Damodar Gullipalli

Damodar Gullipalli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Humanized anti-C5 antibodies and uses thereof
    Patent number: 12098190
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: September 24, 2024
    Assignees: The Trustees of the University of Pennsylvania and, Kira Pharmaceuticals (US) LLC
    Inventors: Wenchao Song, Takashi Miwa, Damodar Gullipalli, Ping Tsui, Sayaka Sato
  • ANTI-C5 ANTIBODIES AND USES THEREOF
    Publication number: 20230227571
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.
    Type: Application
    Filed: January 12, 2023
    Publication date: July 20, 2023
    Inventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
  • Anti-C5 antibodies and uses thereof
    Patent number: 11578137
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: February 14, 2023
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
  • ANTI-FACTOR D ANTIBODIES AND USES THEREOF
    Publication number: 20230032737
    Abstract: This invention relates to selective inhibition of the alternative pathway (AP) of the complement system using an anti-factor D antibody. Specifically, the invention relates to methods of treating an AP-mediated disease or AP-mediated disorder in an individual by contacting the individual with an anti-factor D antibody.
    Type: Application
    Filed: July 26, 2022
    Publication date: February 2, 2023
    Inventors: Wenchao Song, Lin Zhou, Sayaka Sato, Takashi Miwa, Damodar Gullipalli, Madhu Golla
  • Anti-factor D antibodies and uses thereof
    Patent number: 11434279
    Abstract: This invention relates to selective inhibition of the alternative pathway (AP) of the complement system using an anti-factor D antibody. Specifically, the invention relates to methods of treating an AP-mediated disease or AP-mediated disorder in an individual by contacting the individual with an anti-factor D antibody.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: September 6, 2022
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wenchao Song, Lin Zhou, Sayaka Sato, Takashi Miwa, Damodar Gullipalli, Madhu Golla
  • BI-FUNCTIONAL HUMANIZED ANTI-C5 ANTIBODIES AND FACTOR H FUSION PROTEINS AND USES THEREOF
    Publication number: 20220204602
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody or fusion protein thereof. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody fusion protein thereof.
    Type: Application
    Filed: April 24, 2020
    Publication date: June 30, 2022
    Inventors: Wenchao Song, Takashi Miwa, Damodar Gullipalli, Sayaka Sato, Ping Tsui, Yingjie Zhu, Xihua Zhu
  • HUMANIZED ANTI-C5 ANTIBODIES AND USES THEREOF
    Publication number: 20220177556
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.
    Type: Application
    Filed: September 6, 2019
    Publication date: June 9, 2022
    Inventors: Wenchao Song, Takashi Miwa, Damodar Gullipalli, Ping Tsui, Sayaka Sato
  • ANTI-C5A ANTIBODIES AND USES THEREOF
    Publication number: 20220153824
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody.
    Type: Application
    Filed: February 2, 2022
    Publication date: May 19, 2022
    Inventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
  • Anti-C5a antibodies and uses thereof
    Patent number: 11274146
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: March 15, 2022
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
  • COMPOSITION AND METHOD FOR TREATING COMPLEMENT-MEDIATED DISEASE
    Publication number: 20210171592
    Abstract: A recombinant vector having an expression cassette comprising a modified human factor H (hfH) gene is provided, wherein said hfH gene encodes a hfH protein variant comprising SCR1-4, 19-20, and one or more of SCR7, SCR17 and/or SCR18. Also provided are pharmaceutical compositions containing this vector and uses therefor in treating AMD and/or other complement associated diseases.
    Type: Application
    Filed: January 22, 2021
    Publication date: June 10, 2021
    Inventors: Wenchao Song, Damodar Gullipalli, Takashi Miwa
  • Composition and method for treating complement-mediated disease
    Patent number: 10988519
    Abstract: Provided herein is a recombinant viral vector having packaged therein an expression cassette comprising an engineered complement regulator factor H (fH), wherein the gene encodes a hfH protein variant comprising short consensus repeats (SCRs) 1-4, 6-8, and 17-20. Pharmaceutical compositions containing this vector and plasmids comprising nucleic acid sequences that encode the fH protein variant are also provided.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: April 27, 2021
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wenchao Song, Damodar Gullipalli, Takashi Miwa
  • ANTI-C5 ANTIBODIES AND USES THEREOF
    Publication number: 20200385481
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.
    Type: Application
    Filed: March 6, 2018
    Publication date: December 10, 2020
    Inventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
  • ANTI-C5A ANTIBODIES AND USES THEREOF
    Publication number: 20200148754
    Abstract: This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody.
    Type: Application
    Filed: March 23, 2018
    Publication date: May 14, 2020
    Inventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
  • ANTI-FACTOR D ANTIBODIES AND USES THEREOF
    Publication number: 20190359699
    Abstract: This invention relates to selective inhibition of the alternative pathway (AP) of the complement system using an anti-factor D antibody. Specifically, the invention relates to methods of treating an AP-mediated disease or AP-mediated disorder in an individual by contacting the individual with an anti-factor D antibody.
    Type: Application
    Filed: February 9, 2018
    Publication date: November 28, 2019
    Inventors: Wenchao Song, Lin Zhou, Sayaka Sato, Takashi Miwa, Damodar Gullipalli, Madhu Golla
  • COMPOSITION AND METHOD FOR TREATING COMPLEMENT-MEDIATED DISEASE
    Publication number: 20190177381
    Abstract: A recombinant vector having an expression cassette comprising a modified human factor H (hfH) gene is provided, wherein said hfH gene encodes a hfH protein variant comprising SCR1-4, 19-20, and one or more of SCR7, SCR17 and/or SCR18. Also provided are pharmaceutical compositions containing this vector and uses therefor in treating AMD and/or other complement associated diseases.
    Type: Application
    Filed: September 23, 2016
    Publication date: June 13, 2019
    Inventors: Wenchao Song, Damodar Gullipalli, Takashi Miwa