Abstract: The evidence-based outcomes system is a multifunction web-based process to optimize performance of industry-specific programs. The system is applicable to virtually all industries which require optimized performance. However, the system is particularly applicable to the health care industry, which, of course, requires optimized performance. The system is further particularly applicable to bloodless medicine and surgery versus homologous medicine and surgery, which is an application with performance which is particularly sensitive to changes in input to the system. The system is typically implemented with an industry team of experts, a program team which collects and enters relevant data, a technology team which manages the relational database and a business team which uses evidence-based analysis of outcomes to develop and recommend policies that will enhance program financial performance.