Patents by Inventor Dan ARDOUREL
Dan ARDOUREL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260193313Abstract: Provided herein are variant CD86 polypeptides, immunomodulatory proteins comprising variant CD86 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: November 26, 2025Publication date: July 9, 2026Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Dan Ardourel, Joseph L. Kuijper, Steven Dennis Levin
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Publication number: 20260062456Abstract: Provided herein are immunomodulatory proteins comprising variant PD-L1 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: July 21, 2025Publication date: March 5, 2026Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Dan Ardourel, Daniel William Demonte, Joseph L. Kuijper
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Patent number: 12552853Abstract: Provided herein are variant CD86 polypeptides, immunomodulatory proteins comprising variant CD86 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: November 27, 2019Date of Patent: February 17, 2026Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Dan Ardourel, Steven Dennis Levin, Joseph L. Kuijper
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Publication number: 20240002466Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: March 10, 2023Publication date: January 4, 2024Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Dan Ardourel, Daniel William Demonte, Joseph L. Kuijper
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Patent number: 11834490Abstract: Provided herein are immunomodulatory proteins comprising variant CD112 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: July 27, 2017Date of Patent: December 5, 2023Assignee: ALPINE IMMUNE SCIENCES, INC.Inventors: Ryan Swanson, Michael Kornacker, Daniel William Demonte, Mark F. Maurer, Dan Ardourel, Joseph L. Kuijper
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Patent number: 11732022Abstract: Provided herein are immunomodulatory proteins comprising variant PD-L2 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: March 13, 2018Date of Patent: August 22, 2023Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Dan Ardourel, Daniel William Demonte, Joseph L. Kuijper
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Publication number: 20230220039Abstract: Provided herein are immunomodulatory proteins comprising variant PD-L1 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: March 13, 2018Publication date: July 13, 2023Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUJIPER
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Publication number: 20220372106Abstract: Provided herein are variant CD86 polypeptides, immunomodulatory proteins comprising variant CD86 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: November 27, 2019Publication date: November 24, 2022Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Dan ARDOUREL, Steven Dennis LEVIN, Joseph L. KUIJPER
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Publication number: 20210253668Abstract: Provided herein are immunomodulatory proteins comprising variant CD112 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: July 27, 2017Publication date: August 19, 2021Applicant: ALPINE IMMUNE SCIENCES, INC.Inventors: Ryan SWANSON, Michael KORNACKER, Daniel William DEMONTE, Mark F. MAURER, Dan ARDOUREL, Joseph L. KUIJPER
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Publication number: 20210188942Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 29, 2021Publication date: June 24, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210171603Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 29, 2021Publication date: June 10, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210163571Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 28, 2021Publication date: June 3, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210155668Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 28, 2021Publication date: May 27, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210155669Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 28, 2021Publication date: May 27, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210130437Abstract: Provided herein are immunomodulatory proteins comprising variant PD-L2 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: March 13, 2018Publication date: May 6, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210130436Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: March 13, 2018Publication date: May 6, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20190175654Abstract: Provided herein are immunomodulatory proteins comprising variant CD155 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: July 27, 2017Publication date: June 13, 2019Applicant: ALPINE IMMUNE SCIENCES, INC.Inventors: Ryan SWANSON, Michael KORNACKER, Daniel William DEMONTE, Mark F. MAURER, Dan ARDOUREL, Joseph L. KUIJPER