Patents by Inventor Dan Dormady

Dan Dormady has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Clostripain catalyzed amidation of peptides
    Patent number: 6461834
    Abstract: The invention provides a method of producing a polypeptide having a C-terminal &agr;-carboxamide group. It particularly concerns an enzymatic modification of selected substrate polypeptides which result in cleavage of the substrate polypeptide to form a product peptide with a C-terminal arginine residue having an &agr;-carboxamide group (C-terminal “Arg-NH2”). The method includes contacting an aqueous-based solution including (i) ammonia reagent and (ii) the substrate polypeptide with (iii) clostripain.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: October 8, 2002
    Assignee: Bionebraska, Inc.
    Inventors: Dan Dormady, Jay S. Stout, Daniel J. Strydom, Barton Holmquist, Fred W. Wagner