Patents by Inventor Dan Eaton

Dan Eaton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for the Diagnosis and Treatment of Tumor
    Publication number: 20070178486
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: September 27, 2006
    Publication date: August 2, 2007
    Applicant: Genentech, Inc.
    Inventors: Avi Ashkenazi, Dan Eaton, Audrey Goddard, Austin Gurney, William Wood, Thomas Wu
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20070077623
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 7, 2006
    Publication date: April 5, 2007
    Applicant: GENENTECH, INC.
    Inventors: Avi Ashkenazi, David Bolstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Jennie Mather, James Pan, Nicholas Paoni, Margaret Roy, Timothy Stewart, Daniel Tumas, P. Williams, William Wood
  • Interleukin-8 homologous polypeptides and therapeutic uses thereof
    Publication number: 20070025962
    Abstract: The present invention is directed to novel polypeptides having structural homology to IL-8 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treatment and diagnosis of inflammatory diseases.
    Type: Application
    Filed: September 28, 2006
    Publication date: February 1, 2007
    Inventors: Dan Eaton, Dorothy French, J. Grimaldi, Kenneth Hillan, Maria Pisabarro, Kerstin Schmidt, Victoria Smith, Daniel Tumas, Richard Vandlen, Colin Watanabe, P. Williams, William Wood
  • Nucleic acid underexpressed in melanoma
    Publication number: 20070003935
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: April 7, 2005
    Publication date: January 4, 2007
    Inventors: Dan Eaton, Ellen Filvaroff, Mary Gerrilsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Colin Watanabe, William Wood
  • Interleukin-8 homologous polypeptides and therapeutic uses thereof
    Publication number: 20070003545
    Abstract: The present invention is directed to novel polypeptides having structural homology to IL-8 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treatment and diagnosis of inflammatory diseases.
    Type: Application
    Filed: July 8, 2004
    Publication date: January 4, 2007
    Inventors: Dan Eaton, Maria Pisabarro, Kerstin Schmidt, Richard Vandlen, Nancy Chiang, Lauri Diehl
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060275864
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 20, 2004
    Publication date: December 7, 2006
    Applicant: GENENTECH, INC.
    Inventors: Avi Ashkenazi, David Botstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Jennie Mather, James Pan, Nicholas Paoni, Margaret Roy, Timothy Stewart, Daniel Tumas, P. Williams, William Wood
  • Compositions and methods for the treatment of tumor of hematopoietic origin
    Publication number: 20060251662
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: May 4, 2006
    Publication date: November 9, 2006
    Inventors: Wesley Chang, Frederic de Sauvage, Dan Eaton, Allen Ebens, Gretchen Frantz, Jo-Anne Hongo, Hartmut Koeppen, Andrew Polson, Victoria Smith
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060246540
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 29, 2005
    Publication date: November 2, 2006
    Inventors: Avi Ashkenazi, Kevin Baker, David Botstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, Austin Gurney, Ivar Kljavin, Jennie Mather, Mary Napier, James Pan, Nicholas Paoni, Margaret Roy, Timothy Stewart, Daniel Tumas, Colin Watanabe, P. Williams, William Wood, Zemin Zhang
  • Compositions and methods for the treatment of tumor of hematopoietic origin
    Publication number: 20060216232
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: December 21, 2005
    Publication date: September 28, 2006
    Inventors: Wesley Chang, Frederic Sauvage, Dan Eaton, Allen Ebens, Gretchen Frantz, Hartmut Koeppen, Andrew Polson, Victoria Smith
  • Interleukin-8 homologous polypeptides and therapeutic uses thereof
    Publication number: 20060210991
    Abstract: The present invention is directed to novel polypeptides having structural homology to IL-8 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treatment and diagnosis of inflammatory diseases.
    Type: Application
    Filed: March 9, 2004
    Publication date: September 21, 2006
    Inventors: Dan Eaton, Dorothy French, J. Grimaldi, Kenneth Hillan, Maria Pisabarro, Kerstin Schmidt, Victoria Smith, Daniel Tumas, Richard Vandlen, Colin Watanabe, P. Williams, William Wood
  • Human anti-factor IX/IXa antibodies
    Publication number: 20060193851
    Abstract: The invention provides for the isolation, identification, synthesis, expression and purification of antibodies reactive with factor IX (FIX)/factor IXa (IXa). In particular aspects, the invention provides human antibodies reactive with the human FIX Gla domain. The invention further provides compositions especially pharmaceutical compositions, articles of manufacture, and methods of inhibiting the activation of FIX and inhibiting FIX/IXa dependent coagulation.
    Type: Application
    Filed: March 31, 2006
    Publication date: August 31, 2006
    Inventors: Camellia Adams, Brigitte Devaux, Dan Eaton, Philip Hass, J. Judice, Daniel Kirchhofer, Shelley Suggett
  • Interleukin-8 homologous polypeptides and therapeutic uses thereof
    Publication number: 20060183169
    Abstract: The present invention is directed to novel polypeptides having structural homology to IL-8 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treatment and diagnosis of inflammatory diseases.
    Type: Application
    Filed: April 21, 2006
    Publication date: August 17, 2006
    Inventors: Dan Eaton, Maria Pisabarro, Kerstin Schmidt, Richard Vandlen, Nancy Chiang, Lauri Diehl
  • Nucleic acid underexpressed in stomach tumor and lung tumor
    Publication number: 20060160186
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: March 14, 2006
    Publication date: July 20, 2006
    Inventors: Dan Eaton, Ellen Filvaroff, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Colin Watanabe, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060127983
    Abstract: The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: December 6, 2005
    Publication date: June 15, 2006
    Inventors: Kevin Baker, David Botstein, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Mary Napier, Margaret Roy, Daniel Tumas, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060105427
    Abstract: The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: December 6, 2005
    Publication date: May 18, 2006
    Inventors: Kevin Baker, David Botstein, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Mary Napier, Margaret Roy, Daniel Tumas, William Wood
  • Antibodies to a polypeptide encoded by a nucleic acid underexpressed in melanoma
    Publication number: 20060099657
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: April 6, 2005
    Publication date: May 11, 2006
    Inventors: Dan Eaton, Ellen Filvaroff, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Colin Watanabe, William Wood
  • HUMAN ANTI-FACTOR IX/IXA ANTIBODIES
    Publication number: 20060088534
    Abstract: The invention provides for the isolation, identification, synthesis, expression and purification of antibodies reactive with factor IX (FIX)/factor IXa (IXa). In particular aspects, the invention provides human antibodies reactive with the human FIX Gla domain. The invention further provides compositions especially pharmaceutical compositions, articles of manufacture, and methods of inhibiting the activation of FIX and inhibiting FIX/IXa dependent coagulation.
    Type: Application
    Filed: July 8, 2003
    Publication date: April 27, 2006
    Inventors: Camellia Adams, Brigitte Devaux, Dan Eaton, Philip Hass, J. Judice, Daniel Kirchhofer, Shelley Suggett
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060078964
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: August 9, 2002
    Publication date: April 13, 2006
    Inventors: Avi Ashkenazi, Kevin Baker, David Botstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Sophia Kuo, Mary Napier, James Pan, Nicholas Paoni, Margaret Roy, David Shelton, Timothy Stewart, Daniel Tumas, P. Williams, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060073579
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 13, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060073553
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 13, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong