Abstract: A modified immune effector cell may be one in which the functions of a T cell antigen receptor (TCR) and major histocompatibility complexes (MHCI, MHCII) in the modified immune effector cell are inhibited in a T cell. Such a modified immune effector cell may include a chimeric antigen receptor (CAR) targeting GD2. Such a modified immune effector cell may knock out TCR and HLA-A genes expressed by the cell while recognizing surface antigens of tumor cells, so that multiple effects of improving the anti-tumor effect of CAR-T cells, prolonging the survival time of the cells, and reducing the immune rejection response caused by allogeneic cell therapy may be reduced.

Abstract: The present disclosure provides use of Clostridium ghonii combined with a tumor angiogenesis inhibitor in preparing a pharmaceutical product for treating a tumor. The present disclosure further provides a drug for treating a tumor, where the drug includes active ingredients of Clostridium ghonii and a tumor angiogenesis inhibitor.

Abstract: A switch switching method and a related apparatus. The method includes: receiving, by an MIPI switch, an MIPI instruction, and parsing the MIPI instruction preliminarily, to obtain an address and a control instruction in the MIPI instruction; determining, by the MIPI switch, whether the address in the MIPI instruction is the same as an address of the MIPI switch; if the addresses are the same, writing the control instruction into a data register of the MIPI switch; transmitting, by the MIPI switch, the control instruction in the data register of the MIPI switch to a mode identification module; determining, by the mode identification module, which control instruction bits control the MIPI switch, and sending these control instruction bits to a translator in the MIPI switch; and translating, by the translator in the MIPI switch, the control instruction into a component status.

Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: Provided is a method for treating an oil gas, which can realize high-efficiency separation for and recovery of gasoline components, C2, C3, and C4 components. The method first conducts separation of light hydrocarbon components from gasoline components, and then performs subsequent treatment on a stream rich in the light hydrocarbon components, during which it is no longer necessary to use gasoline to circularly absorb liquefied gas components, which significantly reduces the amount of gasoline to be circulated and reduces energy consumption throughout the separation process. Besides, in this method, impurities, such as H2S and mercaptans, in the stream rich in the light hydrocarbon components are removed first before the separation for the components. This ensures that impurities will not be carried to a downstream light hydrocarbon recovery section, thus avoiding corrosion issues caused by hydrogen sulfide in the light hydrocarbon recovery section.

Abstract: An information processing device according to an embodiment includes a memory and one or more hardware processors. The memory includes a flag table storage area to store a flag table in which file information for individually identifying one or more pieces of software is associated with a flag used for execution control of a corresponding one of the pieces of software. When rewrite of first software is detected, the hardware processors: extract first file information being the file information corresponding to the first software; change a first flag corresponding to the first file information to a first value indicating that verification of integrity of the first software is required; change a file of the first software in an authorized manner; and change the first value, which has been changed, to a second value indicating permission of execution of the first software.

Abstract: A method for the treatment of an auditory disease or condition in a human subject is provided comprising administering a therapeutic agent into a bony cavity of a cochlea of the subject that contains neural structures via the Round Window membrane of the cochlea. Also provided are therapeutic agents for use in such methods, as well as method for the delivery of therapeutic agents via the Round Window membrane of the cochlea.

Abstract: A system and method for enabling secure device-to-device (D2D) communication between a plurality of user devices. The method includes providing public and private keys for each of the user devices, the private key arranged to decrypt data encrypted by the corresponding public key. A sender user device creates a digital signature using its private key. The sender double-encrypts a transmission using both the public keys of a recipient user device and a first relay user device. The transmission is transmitted from the sender to the recipient through a plurality of relay user devices. Each relay user device receives the transmission, decrypts a first layer of encryption with its private key, encrypts the transmission with the public key of a subsequent user device; and forwards the data transmission to the subsequent user device. The recipient authenticates the digital signature of the sender using the public key of the sender.

Abstract: An information processing device according to an embodiment includes a memory and one or more hardware processors. The memory includes a flag table storage area to store a flag table in which file information for individually identifying one or more pieces of software is associated with a flag used for execution control of a corresponding one of the pieces of software. When rewrite of first software is detected, the hardware processors: extract first file information being the file information corresponding to the first software; change a first flag corresponding to the first file information to a first value indicating that verification of integrity of the first software is required; change a file of the first software in an authorized manner; and change the first value, which has been changed, to a second value indicating permission of execution of the first software.

Abstract: An outdoor lighting network (OLN) is disclosed as a supplementary or contingency communications infrastructure for smart city systems. The OLN may integrate light points within the network as receivers which are switched from a standard OLN communication protocol to a D2D based protocol upon disruption of a primary smart city systems communications network, wherein each communication protocol includes a respective message prioritization method. Aspects of the disclosure additionally includes methods and apparatus for implementing an outdoor lighting network which can act, in cases of primary communication failure, as a D2D network in order to pass messages from smart city system field devices, through the converted D2D OLN network and to a smart city system central manager for proper handling and distribution of the smart city system field device communications.

Abstract: According to one embodiment, an electronic apparatus used in a vehicle generates a first to fourth log of the vehicle for a first to fourth period, a first to fourth code used to validity of the first to fourth log, a fifth code used to collectively determine a validity of the first log and the second log, a sixth code used to collectively determine a validity of the third log and the fourth log, and a seventh code used to collectively determine a validity of the first to fourth logs, and transmits the first to seventh codes to a server, and transmits the first to fourth logs to the server after a transmission of the first to seventh codes.

Abstract: An outdoor lighting network (OLN) is disclosed as a supplementary or contingency communications infrastructure for smart city systems. The OLN may integrate light points within the network as receivers which are switched from a standard OLN communication protocol to a D2D based protocol upon disruption of a primary smart city systems communications network, wherein each communication protocol includes a respective message prioritization method. Aspects of the disclosure additionally includes methods and apparatus for implementing an outdoor lighting network which can act, in cases of primary communication failure, as a D2D network in order to pass messages from smart city system field devices, through the converted D2D OLN network and to a smart city system central manager for proper handling and distribution of the smart city system field device communications.

Abstract: An electronic device able to communicate using both a long-range and a short-range wireless communication technology. A transceiver of the electronic device switches its operation mode based on a power saving mode of the long-range wireless communication technology. In particular, the electronic device switches between a short-range mode and a long-range mode based on the power saving mode of the long-range communication technology.

Abstract: A system and method for enabling secure device-to-device (D2D) communication between a plurality of user devices. The method includes providing public and private keys for each of the user devices, the private key arranged to decrypt data encrypted by the corresponding public key. A sender user device creates a digital signature using its private key. The sender double-encrypts a transmission using both the public keys of a recipient user device and a first relay user device. The transmission is transmitted from the sender to the recipient through a plurality of relay user devices. Each relay user device receives the transmission, decrypts a first layer of encryption with its private key, encrypts the transmission with the public key of a subsequent user device; and forwards the data transmission to the subsequent user device. The recipient authenticates the digital signature of the sender using the public key of the sender.

Abstract: A method and system for collecting luminaire information is disclosed. A first data collection apparatus collects first data related a plurality of luminaires and a second data collection apparatus collects second data related the plurality of luminaires. Further, a processing device is configured to analyze the first and second data to determine at least one characteristic for each of the plurality of luminaires.

Abstract: A two-stage wireless power transfer system has three distinct components. A first component has a first-stage wireless power transmitter (TX). A second component has a first-stage wireless power receiver (RX) hardwired to a second-stage wireless power transmitter. A third component, which may be a rechargeable, battery-powered device like a cell phone, has a second-stage wireless power receiver. The first stage has TX and RX inductor coils that are substantially larger than the TX and RX coils of the second stage. A Z-gap between the first and second components can be relatively large, while still achieving relatively high overall power transfer efficiency as long as the Z-gap between the second and third components is relatively small.

Abstract: The invention provides a light management information system for an outdoor lighting network system, having a plurality of outdoor light units each including at least one sensor type, where each of the light units communicates with at least one other light unit, at least one user input/output device in communication with at one or more of said outdoor light units, a central management system in communication with light units, said central management system sends control commands and/or information to one or more of said outdoor light units, in response to received outdoor light unit status/sensor information from one or more of said outdoor light units or received user information requests from said user input/output device, a resource server in communication with said central management system, wherein the central management system uses the light unit status/sensor information and resources from the resource server to provide information to the user input/output device and/or reconfigure one or more of the l