Abstract: A wheel assembly comprising a wheel (5) for a wheelchair (1), a gripping ring (6) connected to the wheel, and a gear-shift arrangement (7; 10; 40; 70); the wheel being provided with a wheel axle (17; 47; 77); the gear-shift arrangement being configured to change a gear ratio between the wheel and the gripping ring; the gear-shift arrangement comprising an internal-gear hub (8; 16; 46; 76) comprising a number of internal gears (18, 18?, 18?; 48, 48?, 48?; 78, 78?, 78?), a shift member (15; 45; 75), and a gear selector (9; 11; 41; 71) located on the same side of the wheel as the gripping ring, wherein the gear selector is operatively connected to the shift member (15; 45; 75) that is axially moveable within the internal-gear hub to engage a specific gear of said number of internal gears, and that the gear selector has an inner base portion (12; 42; 72) and an outer handle portion (13; 43; 73) and extends radially away from the wheel axle.

Abstract: The invention relates to a sensor and guide wire assembly (21) for intravascular measurements of physiological variables in a living body, comprising a core wire (22), a first coil (23), a jacket (24), and a second coil (25). The jacket (24) comprises a first end portion (24a), which is crimped onto the core wire (22) and over which a portion of the first coil (23) is threaded, and a second end portion (24b), which is crimped onto the core wire (22) and over which a portion of the second coil (25) is threaded.

Abstract: The present invention provides a dissolvable medical sealing device (3, 4; 6, 7; 9) for closing a wound in vessel. A sealing device (3, 4, 6, 7, 9) according to the invention is made of a material that dissolves by means of physical processes, rather than by means of chemical or biological processes. Such a sealing device (3, 4; 6, 7; 9) can be made of polyethylene glycol, polypropylene glycol, copolymers containing ethylene glycol and propylene glycol, polyvinyl alcohol or polyvinyl pyrolidone, or any combinations thereof.

Abstract: Insertion tool for a medical closure device for the sealing of an opening in a wall of a bodily organ, comprising a tamping force source adapted to deliver a first member to a position at the opening on one side of the wall subsequently to a second member being positioned at the opening on the opposite side of the wall. The tamping force source, which is energized prior to the tamping procedure, can be for example a spring, an elastic band or a pressurized gas container. A tamping spring can be compressed or extended upon loading. The tamping force source can be released in response to a manual operation or be triggered by retraction of the insertion tool.

Abstract: The invention provides a closure device (1) for sealing an incision channel leading through a vessel wall and into the vessel. The closure device (1) comprises a haemostatic material (3), which is contained in the distal end of an elongated insertion assembly (2). The insertion assembly (2), which comprises a stationary part (4) and a retractable part (5) being slidably movable with regard to each other, is adapted to be attached to an introducer (7) being in position in the incision channel, so that the insertion assembly (2) can be slid along the introducer (7) until the distal end of the insertion assembly (2) is in contact with the vessel wall, where the haemostatic material (3) is delivered in the incision channel by a retracting movement of the retractable part (5).

Abstract: The invention provides a closure device (1) for sealing an incision channel leading through a vessel wall and into the vessel. The closure device (1) comprises a haemostatic material (3), which is contained in the distal end of an elongated insertion assembly (2). The insertion assembly (2), which comprises a stationary part (4) and a retractable part (5) being slidably movable with regard to each other, is adapted to be attached to an introducer (7) being in position in the incision channel, so that the insertion assembly (2) can be slid along the introducer (7) until the distal end of the insertion assembly (2) is in contact with the vessel wall, where the haemostatic material (3) is delivered in the incision channel by a retracting movement of the retractable part (5).

Abstract: A femoral compression device (1) for compressive bearing against the femoral artery of a patient, comprising a base plate (2), an inflatable air cushion (4), and an electronic manometer (8) connected to the inflatable air cushion for measurement of the current pressure difference between the pressure prevailing inside the inflatable air cushion and the ambient air pressure. The femoral compression device can further comprise a mechanical device (11; 46) which prevents an air opening leading to the inflatable air cushion from being closed before the manometer is zeroed.

Abstract: An indicator device for visually indicating a pressure of blood inside a blood vessel includes: a body, the body comprising a duct extending in the body and having a sealed proximal end; a distal end portion adapted to be positioned inside the blood vessel and including a liquid inlet opening in fluid communication with the duct; and a window including an at least semi-transparent section configured to enable visual observation of blood entering into the duct via the inlet opening when the inlet opening is located inside the blood vessel.

Abstract: A femoral compression device (1; 41; 51; 61) for compressing a femoral artery of a patient is provided. The femoral compression device (1; 41; 51; 61) comprises a pressure device (7; 21; 31; 42; 55; 62), a compression member (8; 43; 56; 65) for compressive bearing against a puncture site, a base portion (3; 44; 52) provided with two opposing extensions (4, 5; 45, 46; 53, 54), to the ends of which a belt (6), which is adapted to be arranged around the patient's body, can be fixed. According to the invention, the pressure device (7; 21; 31; 42; 55; 62) is characterized by non-uniform overall action constants, such that when a low compression pressure is applied, the pressure device (7; 21; 31; 42; 55; 62) exhibits a small action constant, and when a high compression pressure is applied, the pressure device (7; 21; 31; 42; 55; 62) exhibits a large action constant.

Abstract: The invention provides an air cushion unit (4) for use in conjunction with a compression device for stopping bleeding from puncture wounds. The air cushion unit (4) comprises a base plate (5), an inflatable air cushion (6), which is attached to the base plate (5), and an internal telescopic guide (7), connecting the base plate (5) with the top of the air cushion (6). Throughout the pressurizing of the inflatable air cushion (6), the length of the telescopic guide (7) corresponds to the degree of expansion of the air cushion (6), thereby providing an internal support for the air cushion unit (4), which eliminates undesired, irregular movements of the air cushion (6).

Abstract: The invention provides a femoral compression device (11; 21) for compressing a femoral artery of a patient. The femoral compression device (11; 21) comprises a pressurizing means (12; 22), a compression plate (13; 23) for compressive bearing against a puncture site, a base portion (14; 24) provided with two opposing extensions (15, 16; 25, 26), to the ends of which a belt, which is adapted to be arranged around the patient's body, can be fixed. According to the invention, the pressurizing means is in the form of a spring (12; 22), such as a coil spring (12; 22), the first end of which is connected to the compression plate (13; 23) and the second end of which is operatively connected to a handle (19; 29), which can be operated to adjusting the compression of the spring (12; 22).

Abstract: Methods and systems related to sealing punctures in blood vessels (such as following an angio or PTCA procedure) are disclosed. The invention provides a system to sense the location of a distal portion of a member within a body. The system includes an introducer portion having a distal end adapted to be placed within a body and a pressure sensor. The pressure sensor is in fluid communication with the distal end and is adapted to provide a pulsation which can be sensed by an operator when the distal end is placed within a pulsating portion of the body.

Abstract: The invention provides an air cushion unit (4) for use in conjunction with a compression device for stopping bleeding from puncture wounds. The air cushion unit (4) comprises a base plate (5), an inflatable air cushion (6), which is attached to the base plate (5), and an internal telescopic guide (7), the first end of which is attached to the base plate (5) and the second end of which is attached to the top of the air cushion (6). Throughout the pressurizing of the inflatable air cushion (6), the length of the telescopic guide (7) corresponds to the degree of expansion of the air cushion (6), thereby providing an internal support for the air cushion unit (4), which eliminates undesired, irregular movements of the air cushion (6).

Abstract: A femoral compression device includes a pressure applying device for compressive bearing at a puncture site at a femoral artery of a patient and for applying pressure on the puncture site, a belt adapted to be fixed around the patient's body, and a base plate provided with first and second extensions, with the end of the first extension being closer to the pressure applying device than the end of the second extension and being provided with a fastener in the ends thereof for fastening of an end of the belt. The compression device also includes a support plate, which is attached to the second extension and which is adapted to bear against the patient's body, thereby compensating for the imbalance, which originates from the different extents of the two extensions, that otherwise would be present.

Abstract: Methods and systems related to sealing punctures in blood vessels (such as following an angio or PTCA procedure) are disclosed. The position of a distal end of an introducer assembly in tissue is determined using a pressure sensor. The pressure sensor is connected to the proximal end of the introducer assembly. The introducer assembly has a fluid path between its distal end and its proximal end. Measured blood pressure is outputted as an indication of the position of the distal end of the introducer assembly in the tissue. Proper positioning of a seal is confirmed by placing the introducer assembly such that its distal end is in tissue outside a puncture in a blood vessel wall and observing a characteristic of blood at the proximal end of the introducer assembly.

Abstract: Methods and systems related to sealing punctures in blood vessels (such as following an angio or PTCA procedure) are disclosed. The position of a distal end of an introducer assembly in tissue is determined using a pressure sensor. The pressure sensor is connected to the proximal end of the introducer assembly. The introducer assembly has a fluid path between its distal end and its proximal end. Measured blood pressure is outputted as an indication of the position of the distal end of the introducer assembly in the tissue. Proper positioning of a seal is confirmed by placing the introducer assembly such that its distal end is in tissue outside a puncture in a blood vessel wall and observing a characteristic of blood at the proximal end of the introducer assembly.

Abstract: An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible component is disclosed along with the use of such copolymer in medical devices which may contain a bioactive agent. The present invention also relates to a suture, stents, stent mantles and sealing devices made from the polyaxial copolymer.

Abstract: The invention provides a closure device (1) for sealing an incision channel leading through a vessel wall and into the vessel. The closure device (1) comprises a haemostatic material (3), which is contained in the distal end of an elongated insertion assembly (2). The insertion assembly (2), which comprises a stationary part (4) and a retractable part (5) being slidably movable with regard to each other, is adapted to be attached to an introducer (7) being in position in the incision channel, so that the insertion assembly (2) can be slid along the introducer (7) until the distal end of the insertion assembly (2) is in contact with the vessel wall, where the haemostatic material (3) is delivered in the incision channel by a retracting movement of the retractable part (5).

Abstract: The invention relates to a loading device provided with a tamping mechanism with which two or three functional operations needed in the sealing of punctures in blood vessels can be sequentially executed in one single manual operation. In a preferred embodiment of the tamping mechanism, a cam curve (15) transforms the single manual operation of a tamping button (8) being the one end of a plunger (14) into the retraction of a pusher (5), which has been used to insert an inner seal (1) into the vessel, and, then, the advancement of a tamping tube (10), which pushes an outer seal (2) into engagement with the outer vessel wall. In the end position of the tamping button (8), a recess (23) in the plunger (14) releases a thread (3), which tamps the inner and outer seals (1, 2) together around the intermediate vessel wall, from a retainer (16), thereby completing the third operation step.

Abstract: A tool (101) is provided for inserting and mating two plug members (2, 3) of a sealing device (1) for closing a wound in the wall of a vessel by placing the distal plug member (2) of the sealing device inside the vessel and the proximal plug member (3) on the outside of the vessel. The distal plug member is provided with an elongated retracting means (6) extending from the distal plug member. The tool comprises a gear mechanism (32) coupled to the retracting means for converting a movement of the tool in a proximal direction away from the wound (22), when the distal plug member is anchored in the vessel (20), to a pushing movement for moving the proximal plug member in a direction towards the distal plug member in response to a stretching force in the retracting means.