Patents by Inventor Dan Raleigh

Dan Raleigh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleobindin I variant protein compositions and methods of use
    Patent number: 8703707
    Abstract: The invention relates to Nucleobindin-1 (NUCB1) protein variants that are capable of disaggregating amyloid fibrils as well as inhibiting the formation of fibrils in the presence of physiological concentrations of calcium. Isolated NUCB1 protein variants, nucleic acids encoding the protein variants, cells comprising the isolated nucleic acids, pharmaceutical compositions and kits comprising the variants, methods of making the variants, and therapeutic uses of the variants are provided.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: April 22, 2014
    Assignees: The Rockefeller University, The Research Foundation of State University of New York
    Inventors: Thomas P. Sakmar, Santosh T. Menon, Neeraj Kapoor, Ruchi Gupta, Dan Raleigh
  • NUCLEOBINDIN I VARIANT PROTEIN COMPOSITIONS AND METHODS OF USE
    Publication number: 20110224143
    Abstract: The invention relates to Nucleobindin-1 (NUCB1) protein variants that are capable of disaggregating amyloid fibrils as well as inhibiting the formation of fibrils in the presence of physiological concentrations of calcium. Isolated NUCB1 protein variants, nucleic acids encoding the protein variants, cells comprising the isolated nucleic acids, pharmaceutical compositions and kits comprising the variants, methods of making the variants, and therapeutic uses of the variants are provided.
    Type: Application
    Filed: July 16, 2009
    Publication date: September 15, 2011
    Applicants: The Rockerfeller University, THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
    Inventors: Thomas P. Sakmar, Santosh T. Menon, Neeraj Kapoor, Ruchi Gupta, Dan Raleigh