Abstract: A medical data acquisition device comprising a processing circuitry, the processing circuitry configured to: operate a camera to acquire at least one image during a process for collecting a sample by a tip of a swab making contact with a required contact area on, or within, a body of a patient; analyze the image to determine one or more parameters, the parameters including at least one of (a) a position of the swab with respect to the required contact area, or (b) an orientation of the swab with respect to the required contact area; and perform at least one action based on comparison of the one or more parameters with a positioning criterion.