Patents by Inventor Dan Stark

Dan Stark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of octaketide synthases to produce kermesic acid and flavokermesic acid
    Patent number: 10900056
    Abstract: A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid).
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: January 26, 2021
    Assignees: Danmarks Tekniske Universitet, Københavns Universitet
    Inventors: Birger Lindberg Møller, Bjørn Madsen, Dan Stærk, Finn Thyge Okkels, Johan Andersen-Ranberg, Kenneth Thermann Kongstad, Kim Binderup, Mads Bennedsen, Majse Nafisi, Paiman Khorsand-Jamal, Rubini Maya Kannangara, Uffe Hasbro Mortensen, Ulf Thrane, Rasmus John Normand Frandsen
  • USE OF OCTAKETIDE SYNTHASES TO PRODUCE KERMESIC ACID AND FLAVOKERMESIC ACID
    Publication number: 20200040367
    Abstract: A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid).
    Type: Application
    Filed: July 9, 2019
    Publication date: February 6, 2020
    Inventors: Birger Lindberg Møller, Bjørn Madsen, Dan Stærk, Finn Thyge Okkels, Johan Andersen-Ranberg, Kenneth Thermann Kongstad, Kim Binderup, Mads Bennedsen, Majse Nafisi, Paiman Khorsand-Jamal, Rubini Maya Kannangara, Uffe Hasbro Mortensen, Ulf Thrane, Rasmus John Normand Frandsen
  • Use of heterologous expressed polyketide synthase and small molecule foldases to make aromatic and cyclic compounds
    Patent number: 10519460
    Abstract: A method for producing individual or libraries of tri- to pentadecaketide-derived aromatic compounds of interest by heterologous expression of polyketide synthase and aromatase/cyclase in a recombinant host cell.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: December 31, 2019
    Assignees: DANMARKS TENISKE UNIVESITET, KØBENHAVNS UNIVERSITET, CHR. HANSEN NATURAL COLORS A/S
    Inventors: Rasmus John Normand Frandsen, Uffe Hasbro Mortensen, Hilde Cornelijne Coumou, Rubini Maya Kannangara, Bjørn Madsen, Majse Nafisi, Johan Andersen-Ranberg, Kenneth Thermann Kongstad, Finn Thyge Okkels, Paiman Khorsand-Jamal, Dan Stærk, Birger Lindberg Møller
  • Use of octaketide synthases to produce kermesic acid and flavokermesic acid
    Patent number: 10415066
    Abstract: A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid).
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: September 17, 2019
    Assignees: Danmarks Tekniske Universitet, Københavns Universitet
    Inventors: Birger Lindberg Møller, Bjørn Madsen, Dan Stærk, Finn Thyge Okkels, Johan Andersen-Ranberg, Kenneth Thermann Kongstad, Kim Binderup, Mads Bennedsen, Majse Nafisi, Paiman Khorsand-Jamal, Rubini Maya Kannangara, Uffe Hasbro Mortensen, Ulf Thrane, Rasmus John Normand Frandsen
  • USE OF OCTAKETIDE SYNTHASES TO PRODUCE KERMESIC ACID AND FLAVOKERMESIC ACID
    Publication number: 20190127767
    Abstract: A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid).
    Type: Application
    Filed: June 10, 2016
    Publication date: May 2, 2019
    Inventors: Birger Lindberg Møller, Bjørn Madsen, Dan Stærk, Finn Thyge Okkels, Johan Andersen-Ranberg, Kenneth Thermann Kongstad, Kim Binderup, Mads Bennedsen, Majse Nafisi, Paiman Khorsand-Jamal, Rubini Maya Kannangara, Uffe Hasbro Mortensen, Ulf Thrane, Rasmus John Normand Frandsen
  • USE OF HETEROLOGOUS EXPRESSED POLYKETIDE SYNTHASE AND SMALL MOLECULE FOLDASES TO MAKE AROMATIC AND CYCLIC COMPOUNDS
    Publication number: 20180305709
    Abstract: A method for producing individual or libraries of tri- to pentadecaketide-derived aromatic compounds of interest by heterologous expression of polyketide synthase and aromatase/cyclase in a recombinant host cell.
    Type: Application
    Filed: June 10, 2016
    Publication date: October 25, 2018
    Applicants: DANMARKS TEKNISKE UNIVERSITET, KØBENHAVNS UNIVERSITET, KØBENHAVNS UNIVERSITET
    Inventors: Rasmus John Normand FRANDSEN, Uffe Hasbro MORTENSEN, Hilde Cornelijne COUMOU, Rubini Maya KANNANGARA, Bjørn MADSEN, Majse NAFISI, Johan ANDERSEN-RANBERG, Kenneth Thermann KONGSTAD, Finn Thyge OKKELS, Paiman KHORSAND-JAMAL, Dan STÆRK, Birger Lindberg MØLLER
  • Glycerol enhanced rehydration formulation
    Patent number: 5876763
    Abstract: A rehydration formulation which enhances a subjects ability to quickly recover from dehydration. The rehydration formulation includes a glycerol solution combined with a carbohydrate or sodium to produce a desired result. The glycerol solution combats the ill-effects of dehydration by increasing plasma osmolality thereby preventing loss of osmotic stimulus to thirst and enabling full rehydration to occur.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: March 2, 1999
    Assignee: University of New Mexico
    Inventors: Paul Montner, Dan Stark
  • Glycerol enhanced rehydration formulation
    Patent number: 5811600
    Abstract: A rehydration formulation which enhances a subjects ability to quickly recover from dehydration. The rehydration formulation includes a glycerol solution combined with a carbohydrate or sodium to produce a desired result. The glycerol solution combats the ill-effects of dehydration by increasing plasma osmolality thereby preventing loss of osmotic stimulus to thirst and enabling full rehydration to occur.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: September 22, 1998
    Assignee: University of New Mexico
    Inventors: Paul Montner, Dan Stark
  • Exercise hydration regimen to enhance exercise endurance and performance
    Patent number: 5510335
    Abstract: An exercise regimen which enhances exercise endurance and performance. The regimen includes pre-exercise hydration with a glycerol solution combined with hydration during exercise with a glycerol based solution to prolong hydration effects. The first pre-exercise glycerol solution regimen begins 2 hours prior to exercise and ends 1/2 hour before exercise begins. The hydration during exercise regimen combines glycerol with a carbohydrate and sodium to prolong fluid retention.
    Type: Grant
    Filed: January 6, 1995
    Date of Patent: April 23, 1996
    Assignee: University of New Mexico
    Inventors: Paul Montner, Thomas W. Chick, Dan Stark, Marvin L. Riedesel
  • Exercise hydration regimen to enhance exercise endurance and performance
    Patent number: 5403921
    Abstract: An exercise regimen which enhances exercise endurance and performance. The regimen includes pre-exercise hydration with a glycerol solution combined with hydration during exercise with a glycerol based solution to prolong hydration effects. The first pre-exercise glycerol solution regimen begins 2 hours prior to exercise and ends 1/2 hour before exercise begins. The hydration during exercise regimen combines glycerol with a carbohydrate and sodium to prolong fluid retention.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: April 4, 1995
    Assignee: University of New Mexico
    Inventors: Paul Montner, Thomas W. Chick, Dan Stark, Marvin L. Riedesel